KEGG   Rattus norvegicus (rat): 64532Help
Entry
64532             CDS       T01003                                 

Gene name
Adcy5
Definition
(RefSeq) adenylate cyclase 5
  KO
K08045  adenylate cyclase 5 [EC:4.6.1.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno01100  Metabolic pathways
rno01522  Endocrine resistance
rno04015  Rap1 signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04114  Oocyte meiosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04371  Apelin signaling pathway
rno04540  Gap junction
rno04611  Platelet activation
rno04713  Circadian entrainment
rno04714  Thermogenesis
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04750  Inflammatory mediator regulation of TRP channels
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04913  Ovarian steroidogenesis
rno04914  Progesterone-mediated oocyte maturation
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04918  Thyroid hormone synthesis
rno04921  Oxytocin signaling pathway
rno04923  Regulation of lipolysis in adipocytes
rno04924  Renin secretion
rno04925  Aldosterone synthesis and secretion
rno04926  Relaxin signaling pathway
rno04927  Cortisol synthesis and secretion
rno04928  Parathyroid hormone synthesis, secretion and action
rno04934  Cushing syndrome
rno04935  Growth hormone synthesis, secretion and action
rno04970  Salivary secretion
rno04971  Gastric acid secretion
rno04972  Pancreatic secretion
rno04976  Bile secretion
rno05012  Parkinson disease
rno05030  Cocaine addiction
rno05031  Amphetamine addiction
rno05032  Morphine addiction
rno05034  Alcoholism
rno05163  Human cytomegalovirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05200  Pathways in cancer
rno05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    64532 (Adcy5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    64532 (Adcy5)
   04371 Apelin signaling pathway
    64532 (Adcy5)
   04072 Phospholipase D signaling pathway
    64532 (Adcy5)
   04024 cAMP signaling pathway
    64532 (Adcy5)
   04022 cGMP-PKG signaling pathway
    64532 (Adcy5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    64532 (Adcy5)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    64532 (Adcy5)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    64532 (Adcy5)
   04062 Chemokine signaling pathway
    64532 (Adcy5)
  09152 Endocrine system
   04911 Insulin secretion
    64532 (Adcy5)
   04923 Regulation of lipolysis in adipocytes
    64532 (Adcy5)
   04912 GnRH signaling pathway
    64532 (Adcy5)
   04913 Ovarian steroidogenesis
    64532 (Adcy5)
   04915 Estrogen signaling pathway
    64532 (Adcy5)
   04914 Progesterone-mediated oocyte maturation
    64532 (Adcy5)
   04921 Oxytocin signaling pathway
    64532 (Adcy5)
   04926 Relaxin signaling pathway
    64532 (Adcy5)
   04935 Growth hormone synthesis, secretion and action
    64532 (Adcy5)
   04918 Thyroid hormone synthesis
    64532 (Adcy5)
   04928 Parathyroid hormone synthesis, secretion and action
    64532 (Adcy5)
   04916 Melanogenesis
    64532 (Adcy5)
   04924 Renin secretion
    64532 (Adcy5)
   04925 Aldosterone synthesis and secretion
    64532 (Adcy5)
   04927 Cortisol synthesis and secretion
    64532 (Adcy5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    64532 (Adcy5)
   04270 Vascular smooth muscle contraction
    64532 (Adcy5)
  09154 Digestive system
   04970 Salivary secretion
    64532 (Adcy5)
   04971 Gastric acid secretion
    64532 (Adcy5)
   04972 Pancreatic secretion
    64532 (Adcy5)
   04976 Bile secretion
    64532 (Adcy5)
  09156 Nervous system
   04724 Glutamatergic synapse
    64532 (Adcy5)
   04727 GABAergic synapse
    64532 (Adcy5)
   04725 Cholinergic synapse
    64532 (Adcy5)
   04728 Dopaminergic synapse
    64532 (Adcy5)
   04726 Serotonergic synapse
    64532 (Adcy5)
   04723 Retrograde endocannabinoid signaling
    64532 (Adcy5)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    64532 (Adcy5)
  09149 Aging
   04211 Longevity regulating pathway
    64532 (Adcy5)
   04213 Longevity regulating pathway - multiple species
    64532 (Adcy5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    64532 (Adcy5)
   04714 Thermogenesis
    64532 (Adcy5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    64532 (Adcy5)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    64532 (Adcy5)
  09165 Substance dependence
   05030 Cocaine addiction
    64532 (Adcy5)
   05031 Amphetamine addiction
    64532 (Adcy5)
   05032 Morphine addiction
    64532 (Adcy5)
   05034 Alcoholism
    64532 (Adcy5)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    64532 (Adcy5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    64532 (Adcy5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    64532 (Adcy5)
   05163 Human cytomegalovirus infection
    64532 (Adcy5)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    64532 (Adcy5)
Enzymes [BR:rno01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     64532 (Adcy5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD
Motif
Other DBs
NCBI-GeneID: 64532
NCBI-ProteinID: NP_072122
RGD: 71014
Ensembl: ENSRNOG00000002229
UniProt: Q04400
Position
11q22
AA seq 1262 aa AA seqDB search
MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGA
VTPQQQQRLASRWRGGDDDEDPPLSGDDPLVGGFGFSFRSKSAWQERGGDDGGRGSRRQR
RGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVEVGLEERRGKGRAAEELEPGTGT
VEDGDGSEDGGSSVASGSGTGTVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQ
SSLTMLMAVLVLVCLVMLAFHAARPPLQVVYLAVLAAAVGVILIMAVLCNRAAFHQDHMG
LACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSA
LHLAISLHTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARL
HSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFT
SLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVE
MGMDMIEAISSVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGG
KAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKM
NRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEF
LGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQ
ITIVPHSLFMLSFYLSCFLLLALVVFISVIYACVKLFPTPLQTLSRKIVRSKKNSTLVGV
FTITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESAFNYSLGDEQGFCGS
PQSNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNAD
LLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWK
LQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIAN
FSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDST
YDKAGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIW
GNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPP
LS
NT seq 3789 nt NT seq  +upstreamnt  +downstreamnt
atgtccggctccaaaagcgtgagccccccgggctacgctgcacagacagcagcgtcgccc
gcgccccggggaggcccggagcatcgcgccgcgtggggagaagccgattcccgcgccaat
ggctacccccacgcccccgggggatcgacccgcggctccaccaagcgatctgggggagcg
gtgaccccacaacagcagcagcgcctggctagccgttggcgcggtggcgacgacgatgaa
gaccctccactaagcggtgacgaccctctggtcggaggcttcggcttcagcttccgttct
aagtcggcctggcaggagcgcggcggcgacgacggcggtcgcggcagcaggcggcagcgg
cggggcgcggctggagggggcagcacccgggcgccccctgcgggcggcagtggcagttcg
gcggcggccgcagcagccgcaggtggcacggaggtgcgcccccgctcggtggaggtgggc
ctggaggagcgtcgaggaaaaggccgagcggccgaggagctggagcccggaactggcacc
gtcgaggatggagacgggtccgaggatggaggcagttccgtggcgtcaggctctgggacc
ggcacggtgctgtcgttgggcgcctgctgcctggccttgctgcagatattccgctctaag
aagttcccgtcggacaaactggagcgtctgtaccagcgctatttcttccgcctgaaccag
agcagcctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgctcgctttc
cacgcggcacggcccccgctccaggtagtctacctggccgtgttggcagctgctgtgggc
gtgatccttatcatggctgtgctctgcaaccgtgcagccttccaccaggaccacatgggc
ctggcctgctatgcgctcattgcagtggtgctggccgtccaggtagtgggcctgttgctg
ccacagccacgcagcgcctccgagggcatctggtggaccgtgttcttcatctataccatc
tacaccctgctgcctgtgcgcatgagggctgcggtgctcagcggggtgcttctgtcggct
ctccacttggccatctctctgcacaccaacgcccaggaccagtttctgctgaaacagctt
gtctccaacgtcctcatcttctcttgcaccaacatcgtgggtgtgtgcactcactaccca
gccgaggtctcccagagacaagccttccaggagacccgggagtgcatccaagctcggctc
cactcacagcgggagaaccagcaacaggagcgtctcctgctgtctgtccttccccgtcat
gttgccatggagatgaaagcagacatcaacgccaaacaggaggatatgatgttccacaag
atttacatccagaaacatgacaatgtgagcatcctgtttgctgacatcgaaggcttcact
agcctggcatcccagtgtactgcccaagaactggtcatgaccctcaacgagctcttcgcc
cgctttgacaagttggctgcggagaatcactgcttacggattaagatcctcggggattgt
tactactgtgtctcggggctgcctgaagccagagctgaccacgcccactgctgcgtagag
atgggaatggacatgatcgaggccatctcgtcggtccgggaggtgacaggggtgaacgtg
aacatgcgtgtgggaattcacagcgggagagtacactgcggtgtccttggcctcagaaag
tggcaattcgacgtgtggtctaacgatgtcacactggccaaccacatggaagctggcggc
aaggcaggccgcatccacatcaccaaggccacactcaactacctgaacggggactatgag
gtggagccaggctgtggtggtgagcgcaatgcctacctcaaggagcacagcatcgagacc
ttcctcatcctgcgctgtacccagaagcggaaagaagagaaggccatgatcgccaagatg
aaccgccagagaaccaactccattggacacaatccgcctcactggggagctgagcgcccc
ttctacaaccacttgggtggcaaccaggtgtccaaggaaatgaagaggatgggctttgag
gaccccaaggacaagaatgcccaggaaagtgccaaccctgaggatgaagtggacgagttt
ctgggtcgagccatcgatgccaggagtattgacagactgcgatccgaacacgtccgaaag
ttcctcttgacctttagggagcccgacttagagaagaagtactccaagcaggtggatgac
cgatttggtgcctatgtggcctgtgcctcgcttgttttcctcttcatctgctttgtccag
atcaccattgtgccccactccctgttcatgctgagcttctacctgtcgtgtttcctgcta
ctggccttggtggtgtttatatctgtgatctacgcctgtgtgaagctcttccctactccc
ctgcagacactctccaggaagatagtgcgatccaagaagaacagcaccctggtcggggtg
ttcaccatcaccctggtgttcctctcggcttttgtcaacatgttcatgtgcaactctaag
aacctggtgggttgcctggcagaggagcacaacatcacggtgaaccaggtgaacgcatgt
catgtgatggagtcggccttcaactacagcctgggcgacgagcagggcttctgtggcagc
ccccagtccaactgcaacttcccagagtacttcacctacagcgtgctgctcagcctgctg
gcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatc
gagctcatctacgtgctcatcgtagaggtgcccggtgtcacactctttgacaacgctgac
cttctggtcaccgccaatgccatagacttcagcaacaacgggacctcccagtgccctgag
catgcgaccaaggtggcgctgaaggtggtgacgcccatcatcatctctgtcttcgtgctg
gctctgtatctgcatgctcagcaggtggaatccactgctcgccttgacttcctctggaaa
ctgcaggccacagaagagaaggaggagatggaggagctgcaggcctacaaccggcgcttg
ctgcacaacattctgcccaaggacgtggctgcccacttcctggcccgggagcggcgcaat
gatgaactgtactaccaatcctgcgagtgcgtggctgtcatgtttgcctccatcgccaac
ttctccgaattctacgtggagctagaggccaacaatgagggcgttgaatgcctacggctg
ctcaatgagatcatcgcagactttgatgagatcatcagtgaggatcggttcaggcagctg
gaaaagatcaagaccataggtagcacctacatggctgcctctggcctcaacgactccacc
tatgacaaggcaggcaagacccacatcaaggctcttgcagacttcgccatgaagctgatg
gaccaaatgaagtacatcaatgagcactccttcaacaacttccagatgaagatcgggctt
aacattggacctgtagtggctggggtcattggggctcgcaagcctcagtatgacatctgg
ggcaatacagtaaatgtggccagccgtatggacagcactggggtgcctgaccgcatccag
gttactacagatatgtaccaggtgctggccgccaacacataccagctggagtgccggggt
gtggtcaaggtcaagggcaagggtgagatgatgacctacttcctcaatggagggcctccc
ctcagttag

DBGET integrated database retrieval system