KEGG   Rattus norvegicus (rat): 79243Help
Entry
79243             CDS       T01003                                 

Gene name
Hsd17b2
Definition
(RefSeq) hydroxysteroid (17-beta) dehydrogenase 2
  KO
K13368  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno01100  Metabolic pathways
rno04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    79243 (Hsd17b2)
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    79243 (Hsd17b2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     79243 (Hsd17b2)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     79243 (Hsd17b2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: adh_short adh_short_C2 DUF1776 KR Polysacc_synt_2 NmrA Epimerase
Motif
Other DBs
NCBI-GeneID: 79243
NCBI-ProteinID: NP_077367
RGD: 621803
Ensembl: ENSRNOG00000013982
UniProt: Q62730
Position
19q12
AA seq 381 aa AA seqDB search
MNPFSSESAWLCLTATAVLGGMLLCKAWSSGQLRSQVVCLAGLWGGACLLSLSLLCSLFL
LSVSCFFLLYVSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGP
GAEELRKNCSERLSVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGEL
IPMTVYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAMIPFQMVAAYASTKAAI
SMFSAVIRQELAKWGVKVVTIHPGGFQTNIVGSQDSWDKMEKEILDHFSKEIQENYGQEY
VHTQKLALPVMREMSNPDITPVLRDIQHAICAKNPSSFYCSGRMTYLWICFAAYSPISLL
DYILKNYFTPKLMPRALRTAS
NT seq 1146 nt NT seq  +upstreamnt  +downstreamnt
atgaacccgttttcctctgagtcagcatggctctgcttgactgccactgcggtgctgggg
ggcatgcttctctgcaaagcctggagttcagggcagctaaggagccaggtggtgtgtctg
gctggcctctggggaggtgcctgcctgctcagcctgtccctcctctgcagcttgttcctc
ttatcggtgtcctgcttcttccttctgtatgtgagttcatctgaccaagacttgttacct
gtggatcaaaaggctgtgctggtgacaggtgccgattccggtttcggtcatgctttggcc
aagcacctggacaagctgggtttcacagtgtttgctggagtgctggataaagagggccca
ggagcggaggaattgaggaaaaactgctctgagcgcctttcggtgctccagatggatgtc
accaagccagagcagataaaagatgttcacagcgaagtcgcagagaagatacaagacaaa
ggactgtgggctgtggtcaacaatgctggggtcttgcactttccgatcgacggggaactc
attcccatgaccgtgtacagaaaatgcatggcagtgaacttcttcggagccgtcgaggtc
accaaggtgtttctgcctctacttagaaagtccaaggggaggctggttaacgtcagcagc
atgggagccatgattccatttcagatggtggccgcctacgcctccacgaaggcagctata
agcatgttctcagccgtcatcaggcaagagcttgccaaatggggagtcaaagtcgtgacc
atccatcctggaggcttccaaacaaacatcgtaggctcacaggacagttgggataaaatg
gagaaggagatcctggaccacttttccaaagagattcaggagaactatggacaggaatat
gtccatacgcagaagctcgccctcccggtcatgagagagatgtccaacccggatatcacc
cctgtgctgcgggacatccagcacgccatttgtgccaagaacccctcttccttttattgc
tcagggagaatgacttacctgtggatctgcttcgcggcctactccccgatcagcttattg
gactatattttgaaaaactattttactccaaaactcatgccaagagctttaaggacagca
agttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (50)   

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