KEGG   Rattus norvegicus (rat): 84420
Entry
84420             CDS       T01003                                 

Gene name
Adcy7
Definition
(RefSeq) adenylate cyclase 7
  KO
K08047  adenylate cyclase 7 [EC:4.6.1.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno01100  Metabolic pathways
rno01522  Endocrine resistance
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04114  Oocyte meiosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04371  Apelin signaling pathway
rno04540  Gap junction
rno04611  Platelet activation
rno04713  Circadian entrainment
rno04714  Thermogenesis
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04727  GABAergic synapse
rno04750  Inflammatory mediator regulation of TRP channels
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04913  Ovarian steroidogenesis
rno04914  Progesterone-mediated oocyte maturation
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04918  Thyroid hormone synthesis
rno04921  Oxytocin signaling pathway
rno04923  Regulation of lipolysis in adipocytes
rno04925  Aldosterone synthesis and secretion
rno04926  Relaxin signaling pathway
rno04927  Cortisol synthesis and secretion
rno04928  Parathyroid hormone synthesis, secretion and action
rno04934  Cushing syndrome
rno04935  Growth hormone synthesis, secretion and action
rno04970  Salivary secretion
rno04971  Gastric acid secretion
rno04972  Pancreatic secretion
rno04976  Bile secretion
rno05032  Morphine addiction
rno05163  Human cytomegalovirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05200  Pathways in cancer
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    84420 (Adcy7)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    84420 (Adcy7)
   04371 Apelin signaling pathway
    84420 (Adcy7)
   04020 Calcium signaling pathway
    84420 (Adcy7)
   04072 Phospholipase D signaling pathway
    84420 (Adcy7)
   04024 cAMP signaling pathway
    84420 (Adcy7)
   04022 cGMP-PKG signaling pathway
    84420 (Adcy7)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    84420 (Adcy7)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    84420 (Adcy7)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    84420 (Adcy7)
   04062 Chemokine signaling pathway
    84420 (Adcy7)
  09152 Endocrine system
   04911 Insulin secretion
    84420 (Adcy7)
   04923 Regulation of lipolysis in adipocytes
    84420 (Adcy7)
   04912 GnRH signaling pathway
    84420 (Adcy7)
   04913 Ovarian steroidogenesis
    84420 (Adcy7)
   04915 Estrogen signaling pathway
    84420 (Adcy7)
   04914 Progesterone-mediated oocyte maturation
    84420 (Adcy7)
   04921 Oxytocin signaling pathway
    84420 (Adcy7)
   04926 Relaxin signaling pathway
    84420 (Adcy7)
   04935 Growth hormone synthesis, secretion and action
    84420 (Adcy7)
   04918 Thyroid hormone synthesis
    84420 (Adcy7)
   04928 Parathyroid hormone synthesis, secretion and action
    84420 (Adcy7)
   04916 Melanogenesis
    84420 (Adcy7)
   04925 Aldosterone synthesis and secretion
    84420 (Adcy7)
   04927 Cortisol synthesis and secretion
    84420 (Adcy7)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    84420 (Adcy7)
   04270 Vascular smooth muscle contraction
    84420 (Adcy7)
  09154 Digestive system
   04970 Salivary secretion
    84420 (Adcy7)
   04971 Gastric acid secretion
    84420 (Adcy7)
   04972 Pancreatic secretion
    84420 (Adcy7)
   04976 Bile secretion
    84420 (Adcy7)
  09156 Nervous system
   04724 Glutamatergic synapse
    84420 (Adcy7)
   04727 GABAergic synapse
    84420 (Adcy7)
   04725 Cholinergic synapse
    84420 (Adcy7)
   04723 Retrograde endocannabinoid signaling
    84420 (Adcy7)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    84420 (Adcy7)
  09149 Aging
   04211 Longevity regulating pathway
    84420 (Adcy7)
   04213 Longevity regulating pathway - multiple species
    84420 (Adcy7)
  09159 Environmental adaptation
   04713 Circadian entrainment
    84420 (Adcy7)
   04714 Thermogenesis
    84420 (Adcy7)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    84420 (Adcy7)
  09165 Substance dependence
   05032 Morphine addiction
    84420 (Adcy7)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    84420 (Adcy7)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    84420 (Adcy7)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    84420 (Adcy7)
   05163 Human cytomegalovirus infection
    84420 (Adcy7)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    84420 (Adcy7)
Enzymes [BR:rno01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     84420 (Adcy7)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N
Other DBs
NCBI-GeneID: 84420
NCBI-ProteinID: NP_445848
RGD: 619966
Ensembl: ENSRNOG00000014776
UniProt: F1LQT1
Position
19p11
AA seq 1100 aa
MPAKGRYFLNEGDEGPKQAALYEKYRLTSQHGPLLLLLLLVAVATCIALVSIVFSHEDLR
RHQAVLGTAFFMLTLFVALYVLVYVECLAQRWLRVLALLTWACLMILGSVLMWDSLENEA
YAWEQVPFFLFIVFVVYVLLPLSTRAAIAVGVASTISHLLVFGAVTRAFKTSMSSTQLGL
QLLANAVILLGGNFTGAFHKHQLQDASRDLFIYTVKCIQIRRKLRVEKRQQENLLLSVLP
AHISMGMKLAIIERLKEGGDRHYTPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPK
ELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAI
KQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITE
ATLNHLDKAYEVEDGHGEQRDPYLKEMNIRTYLVIDPRSQQPPLPSHHLSKPKGDATLKM
RASVRVTRYLESWGAARPFAHLNHRESVSSSEIPIPNGRRQKAIPLRRHRAPDRSASPKG
RLEDDCDDEMLSAIEGLSSTRPCCSKSDDFHTFGPIFLEKGFEREYRLVPIPRARYDFAC
ASLVFVCILLVHLLVMPRMATLGLSFGLVACLLGLVLSFCFATEFSRCLPARSTLQAISE
SVETQPLLRLSLVVVTVGSLLTVAIINMPLTFNPGPEQPGDNETSPLAARNRVGTPCELL
PYYTCSCVLGFIACSVFLRMSLELKAMLLTVALVAYLLLFNLSPCWQVSGNSTETNSTHR
TRRLLSAEQSMNSHTLALGAQMTAPSPSSCLERDLKTMINFYLVLFYATLILLSRQIDYY
CRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKAAEDWYHQSYDCVCV
MFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAA
AGLSVPSGHENQDLERKHVHIGVLVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAG
VIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKG
ELRTYFVCTDTAKFQGLGLN
NT seq 3303 nt   +upstreamnt  +downstreamnt
atgccagccaaggggcgctacttcctaaatgagggtgacgaaggccccaagcaggcagcg
ctctatgagaagtacaggctcaccagccagcacgggccactgctgctcctgctcctcctg
gtggctgtggccacctgcatcgccctcgtcagcatcgtcttcagccatgaggatctccgc
agacaccaggctgtcctgggcactgcgttcttcatgctgacgctgtttgtggctctctat
gtgctggtgtatgttgagtgcctagcacagcgatggctgcgcgtcttggctctactcacc
tgggcttgcctcatgatactaggctccgtgctgatgtgggactccttggagaatgaagcc
tatgcgtgggagcaggtgcctttcttcctgttcatcgtctttgtggtgtacgtactgttg
cctctcagcacgagggcagctatcgcggtgggcgtagcctccaccatctcccatctcctg
gtgtttggagctgtgacaagagccttcaagacatccatgtccagcacacagctggggctg
cagctcctggccaatgccgttatccttctgggtgggaacttcaccggtgccttccacaag
caccagcttcaggacgcttcgagggatctcttcatctacaccgtcaagtgtatccagatc
cgccggaagcttcgcgtggagaagcgccagcaggagaacctgctgctttcagtgctccca
gctcacatctccatgggtatgaagctggccatcattgaacgcctcaaagagggtggtgac
cgccactacacgcctgacaacaactttcacagcctctatgtcaagcggcaccagaacgtc
agcatcttgtatgcagacatcgtgggtttcacgaggctggccagcgactgctctcccaag
gagctagtggtggtgctcaacgagctgtttgggaagtttgaccagattgccaaggccaac
gagtgcatgcggatcaagatcctgggtgactgctactactgcgtgtcaggcctgcctgtg
tcgctgcccacgcacgcccgcaactgtgtgaagatgggtctggacatatgtgaggccatt
aagcaggtgcgtgaggccaccggagtggacatcagcatgcgtgtgggcattcactctggg
aatgtcctgtgtggggtcatcgggctccgcaagtggcagtatgacgtgtggtcccatgac
gtgtccctggccaacaggatggaggcagctggagtccctggccgggtgcacatcacagag
gcgacactgaatcacctggacaaggcatacgaggtggaggacgggcacggggagcagcgc
gacccctatctgaaagagatgaacatccgtacctacttggtgattgacccccggagtcag
cagccgcccctacccagccaccacctgtccaagcccaagggggatgcaactctgaagatg
cgggcttccgtgcgtgtaacccgctatctggagtcctggggggcagcgcggccctttgca
cacctcaaccaccgggagagcgtgagcagcagtgagatccccatccccaacggacggagg
cagaaggccattcctctgcgtcgacaccgtgcccctgataggagtgcatcccccaaggga
cgcctggaagatgactgtgatgacgagatgctgtcagccattgaggggctcagctccacc
aggccctgctgctccaagtctgatgacttccacacctttggtcccatcttcctggagaag
ggctttgagcgtgagtaccgcctggtgcccatcccccgggctcgctatgacttcgcctgt
gccagccttgtcttcgtctgcatcctgcttgtccacctcctagtgatgcccaggatggca
actctgggcttgtcctttgggctggtggcctgcctgctggggctggttctaagcttctgc
tttgctactgagttctcgaggtgccttccagcccgaagtacactccaggccatctcggag
agtgtggagacacagcccctgctcagactttccctggttgtggtgactgttggcagctta
ctgactgttgccatcatcaacatgccactgacatttaacccaggcccagagcagcctgga
gacaatgagacaagcccactggctgcaaggaacagagttgggaccccatgtgaactcctc
ccgtactacacctgcagctgcgtcctgggcttcattgcatgctctgttttcctgcggatg
agcctggaactgaaggccatgttgctgacggtggccttggtggcctacctgctgctcttc
aacctctccccatgctggcaggtctcaggcaacagcacagagaccaacagcacacacagg
acacgtcggctcctgtctgcagaacaaagcatgaacagccacacccttgctctgggggct
cagatgactgccccctcccccagcagttgtttagagagagacctgaagaccatgatcaac
ttctacctggtcctgttctatgccaccctcatcttgctgtctagacagattgactattac
tgccgcttggactgtctgtggaagaagaagtttaagaaggagcatgaggagtttgaaaca
atggagaatgtgaaccgcctcctcctagagaatgttctgccagcacatgtggctgcccac
ttcatcggtgacaaggcagctgaggactggtaccatcaatcttatgactgtgtctgtgtc
atgtttgcatccgttccggacttcaaagtgttctatactgagtgtgatgtcaacaaagaa
ggattggagtgccttcgcctgctgaatgagatcattgctgattttgacgagctgctgctg
aagcccaagttcagtggtgtggagaagatcaagaccattggcagcacctacatggctgct
gcagggctcagtgtcccctcaggacatgagaaccaggacctggagcggaagcatgtgcac
attggtgtcttggtggagtttagcatggccctgatgagcaagctggatggaatcaacagg
cactccttcaactccttccgcctccgagttggcataaaccacggccctgtgattgctgga
gtgattggcgcacgcaagcctcagtatgacatctggggaaacacagtcaatgttgccagc
cgcatggagagcaccggagagcttgggaagatccaggttaccgaggagacgtgcaccatc
ctccagggactgggatattcttgtgagtgccgtgggctcatcaacgtcaaaggcaaaggg
gagctgcggacttactttgtttgtacagacactgccaagtttcaagggctggggctaaac
tga

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