KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104682751
Entry
104682751         CDS       T03989                                 
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
  KO
K03099  son of sevenless
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01521  EGFR tyrosine kinase inhibitor resistance
rro01522  Endocrine resistance
rro04010  MAPK signaling pathway
rro04012  ErbB signaling pathway
rro04014  Ras signaling pathway
rro04062  Chemokine signaling pathway
rro04068  FoxO signaling pathway
rro04072  Phospholipase D signaling pathway
rro04150  mTOR signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04510  Focal adhesion
rro04540  Gap junction
rro04630  JAK-STAT signaling pathway
rro04650  Natural killer cell mediated cytotoxicity
rro04660  T cell receptor signaling pathway
rro04662  B cell receptor signaling pathway
rro04664  Fc epsilon RI signaling pathway
rro04714  Thermogenesis
rro04722  Neurotrophin signaling pathway
rro04810  Regulation of actin cytoskeleton
rro04910  Insulin signaling pathway
rro04912  GnRH signaling pathway
rro04915  Estrogen signaling pathway
rro04917  Prolactin signaling pathway
rro04926  Relaxin signaling pathway
rro04935  Growth hormone synthesis, secretion and action
rro05034  Alcoholism
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05163  Human cytomegalovirus infection
rro05165  Human papillomavirus infection
rro05200  Pathways in cancer
rro05205  Proteoglycans in cancer
rro05206  MicroRNAs in cancer
rro05207  Chemical carcinogenesis - receptor activation
rro05208  Chemical carcinogenesis - reactive oxygen species
rro05210  Colorectal cancer
rro05211  Renal cell carcinoma
rro05213  Endometrial cancer
rro05214  Glioma
rro05215  Prostate cancer
rro05220  Chronic myeloid leukemia
rro05221  Acute myeloid leukemia
rro05223  Non-small cell lung cancer
rro05224  Breast cancer
rro05225  Hepatocellular carcinoma
rro05226  Gastric cancer
rro05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104682751 (SOS2)
   04012 ErbB signaling pathway
    104682751 (SOS2)
   04014 Ras signaling pathway
    104682751 (SOS2)
   04630 JAK-STAT signaling pathway
    104682751 (SOS2)
   04068 FoxO signaling pathway
    104682751 (SOS2)
   04072 Phospholipase D signaling pathway
    104682751 (SOS2)
   04151 PI3K-Akt signaling pathway
    104682751 (SOS2)
   04150 mTOR signaling pathway
    104682751 (SOS2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104682751 (SOS2)
   04540 Gap junction
    104682751 (SOS2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104682751 (SOS2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    104682751 (SOS2)
   04660 T cell receptor signaling pathway
    104682751 (SOS2)
   04662 B cell receptor signaling pathway
    104682751 (SOS2)
   04664 Fc epsilon RI signaling pathway
    104682751 (SOS2)
   04062 Chemokine signaling pathway
    104682751 (SOS2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    104682751 (SOS2)
   04912 GnRH signaling pathway
    104682751 (SOS2)
   04915 Estrogen signaling pathway
    104682751 (SOS2)
   04917 Prolactin signaling pathway
    104682751 (SOS2)
   04926 Relaxin signaling pathway
    104682751 (SOS2)
   04935 Growth hormone synthesis, secretion and action
    104682751 (SOS2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104682751 (SOS2)
  09159 Environmental adaptation
   04714 Thermogenesis
    104682751 (SOS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104682751 (SOS2)
   05206 MicroRNAs in cancer
    104682751 (SOS2)
   05205 Proteoglycans in cancer
    104682751 (SOS2)
   05207 Chemical carcinogenesis - receptor activation
    104682751 (SOS2)
   05208 Chemical carcinogenesis - reactive oxygen species
    104682751 (SOS2)
   05231 Choline metabolism in cancer
    104682751 (SOS2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    104682751 (SOS2)
   05225 Hepatocellular carcinoma
    104682751 (SOS2)
   05226 Gastric cancer
    104682751 (SOS2)
   05214 Glioma
    104682751 (SOS2)
   05221 Acute myeloid leukemia
    104682751 (SOS2)
   05220 Chronic myeloid leukemia
    104682751 (SOS2)
   05211 Renal cell carcinoma
    104682751 (SOS2)
   05215 Prostate cancer
    104682751 (SOS2)
   05213 Endometrial cancer
    104682751 (SOS2)
   05224 Breast cancer
    104682751 (SOS2)
   05223 Non-small cell lung cancer
    104682751 (SOS2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    104682751 (SOS2)
   05160 Hepatitis C
    104682751 (SOS2)
   05163 Human cytomegalovirus infection
    104682751 (SOS2)
   05165 Human papillomavirus infection
    104682751 (SOS2)
  09165 Substance dependence
   05034 Alcoholism
    104682751 (SOS2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104682751 (SOS2)
   01522 Endocrine resistance
    104682751 (SOS2)
SSDB
Motif
Pfam: RasGEF RasGEF_N RhoGEF PH IQ_SEC7_PH
Other DBs
NCBI-GeneID: 104682751
NCBI-ProteinID: XP_010387785
UniProt: A0A2K6QBZ6
Position
5:complement(6513637..6628916)
AA seq 1332 aa
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFNEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCPFYSHQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVVFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLA
IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPAIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPS
TPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq 3999 nt   +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccttacgagttcttcagtgaggagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagaatatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgat
ataggtttggtttctctctgtgaagatgaacctagttcttccggtgaattaaactactat
gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatt
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcgtttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttaatgaacatttcaataaattgatggccagacctgcagttgctcta
cactttcagtccattgctgatggctttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtatatcactgttggcactattttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagcattcacctagacgccgacctggagat
cctgtttgccctttttatagtcaccaattaagaagcaaacacctggctatcaaaaaaatg
aatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggagggaccattgacaagaatcggtgccaaacatgaacgacatattttt
ctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcggcttccaggt
tacagtagtgcagaatataggttaaaagaaaaatttgtcatgaggaaaatacaaatttgt
gataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaagatgagaac
agcgtagtatttgctgctaagtctgctgaagaaaaaaacaactggatggcagcccttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattactgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtatatcgttttgtagtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatccccattattaaa
ggaggaactgtagtgaagttaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaattgctgagc
ttactgattgaacggtttgaaatcccagagccagaacctactgacgcagacaaattggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacatcatttttat
gactttgaaagagatttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaatcgctaagatcatcaagaggaagaagcaa
gctcaggcaaacggaataagccataatattacctttgaaagtccacctccagcaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagttcaaccatct
gaacttgtaggaagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggttgcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatatctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagaccgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcagccttactgtttacgg
atagaaccagatatgaggagattctttgaaaaccttaaccccatgggaaatgcgtctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaacctcgaaactgcaaa
cagccacctcgatttcctagaaaatcaactttctccttgaaatctcctggaataaggcct
aacacaggccgacatggctctacctcaggtactttacgaggtcacccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaatcaacagtg
tcagcaccaacttctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtatttttagatgtggatctcaacagctcctgtggcagcaatagcatctttgctcca
gtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacataaactaagt
gaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatatgaaatctgatgatgatcctcctgctattccaccgagacagcct
cctcctcccaaggtaaaacccagagttcctgttcctactggtgcatttgatgggcctctg
catagtccacctccaccaccaccaagagatcctcttcctgatacccctccaccggttccc
cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccactgggg
catcttcacagagattcagactggctcagagacattagtacgtgtccaaattcgccaagc
actcctcctagcacaccctctccaagggtaccacgtcgatgctatgtgctcagttctagt
cagaataatcttgctcatcctccagctccccctgttccaccaaggcagaattcaagccct
catctgccaaaactgccaccaaagacttacaaacgggagctttcgcaccccccattgtac
agactgcctttgctagaaaatgcagaaactccccaatga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (48)   
   KEGG PATHWAY (48)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (5)   
   Pfam (5)   
All databases (68)   

Download RDF
DBGET integrated database retrieval system