KEGG   Streptomyces alboflavus: SMD44_02623
Entry
SMD44_02623       CDS       T05221                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
salf  Streptomyces alboflavus
Pathway
salf00010  Glycolysis / Gluconeogenesis
salf00020  Citrate cycle (TCA cycle)
salf00620  Pyruvate metabolism
salf00785  Lipoic acid metabolism
salf01100  Metabolic pathways
salf01110  Biosynthesis of secondary metabolites
salf01120  Microbial metabolism in diverse environments
salf01200  Carbon metabolism
salf01210  2-Oxocarboxylic acid metabolism
Module
salf_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:salf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    SMD44_02623 (aceE)
   00020 Citrate cycle (TCA cycle)
    SMD44_02623 (aceE)
   00620 Pyruvate metabolism
    SMD44_02623 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    SMD44_02623 (aceE)
Enzymes [BR:salf01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     SMD44_02623 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N
Other DBs
NCBI-ProteinID: ARX83208
UniProt: A0A1Z1W9Y2
Position
2837786..2840533
AA seq 915 aa
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLSEQQLDGFRQ
EKSKAPHALSSYPHPRSMPDFWEFPTVSMGLGPLGAIFQARMNRYMAARDIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNTTPDGQFQTYATETGAYIRDHFFGDDQRLR
AMVEGMTDDQILHLGRGGHDHKKIFAAFSAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHLPITDKQLEDGAPPYYHPGRNSEEIQYMHDRRKGLGGYVP
TRVVRSEPLRLPEDKTYAAVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVQDGLRRMYGSSADHPQGEDVFYYLTVYNEPIQH
PAEPENVDVEGILKGIHRFKAGEQGAIPAQILASGVAVPWAVEAQRILASEWNVKADVWS
ATSWNELRREAVEVERHNLLHPEEEQRVPYVTRKLSSAEGPFVAVSDWMRSVPDQISRWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAREGKIDRSVLKQAIDRYQL
LDVAAADPGAAGGDA
NT seq 2748 nt   +upstreamnt  +downstreamnt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gatttcgatccagaagagacccaggaatggctcgactccctcgacgccgccgtcgacgag
cgcggccgcgagcgggcccgctatctgatgctccgcctgatcgagcgcgcccgcgagaag
cgcgtcgccgtgcccgagatgcgcagcacggactacgtcaacacgatcgccaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaaggtcctgaacgcgacccgctgg
aacgcggccgtgatggtgtcccgcgcgcagcgccccggcatcggggtgggcggccacatc
gccaccttcgcctcctcggcgtcgctgtacgacgtgggtttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccaggggcacgcctcccccggcatc
tacgcccgcgccttcctcctcgaccggctctccgagcagcagctcgacgggttccggcag
gagaagtccaaggccccgcacgccctgtcgtcgtatccccacccgcgcagcatgccggac
ttctgggagttcccgacggtctccatgggcctcggcccgctcggcgcgatcttccaggcg
cggatgaaccgctacatggcggcgcgcgacatcgccgacacctccaagtcgcacgtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcgggcagttgtccatcgcc
gcgcgcgaggggctcgacaacctcaccttcgtcgtcaactgcaatctgcagcgcctggac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgcagttccgcggcgcc
ggatggaacgtcatcaagctggtgtgggaccgcagttgggacccgctgctcgcgcaggac
cgggacggcatcctggtcaacaagctgaacaccacgcccgacggccagttccagacgtac
gccaccgagaccggcgcctacatccgcgaccacttcttcggtgacgaccagcggctgcgc
gccatggtcgagggcatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatcttcgcggcgttctccgcggccaaggcccacaagggccagccgacggtg
atcctggcccagaccgtcaagggctggacgctcggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagggcttccgcgaccggctgcac
ctgccgatcacggacaagcagctggaggacggcgccccgccgtactaccacccgggccgg
aactcggaagagatccagtacatgcacgaccgccgcaagggcctcggcggctatgtcccg
acccgcgtggtgcgctccgagccactgcgcctgcccgaggacaagacgtacgcagccgtg
aagaagggctccgggcagcagtccatcgccaccaccatggcgtttgtgcggctcctgaag
gacctcatgcgggacaaggagatcggcaagcgttttgtgctgatcgcgcccgatgagtac
cgcaccttcggcatggactcgttcttcccgagtgcgaagatctacaacccgctcggccag
cagtacgaggccgtggaccgggatctgctgctcgcctacaaggagtccccgaccgggcag
atgctgcacgacgggatctccgaggcgggctgcacggcgtccctgatcgccgcgggctcg
gcctacgccacccacggcgaaccgctgatcccggtgtacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatggccgaccagctcgcgcgcggattcgtc
ctgggcgcgaccgcaggacgcacgaccctgaccggtgagggtctgcagcacgccgacggg
cactcgcagctgctcgcctcgaccaacccgggctgtgtcgcctacgacccggccttcggc
ttcgagatcgcgcacatcgtccaggacggcctgcgccggatgtacggctcgtcggcggac
cacccgcagggcgaggacgtcttctactacctgacggtctacaacgagccgatccagcac
ccggccgagcccgagaacgtggacgtcgagggcatcctcaagggcatccaccgcttcaag
gcgggcgagcagggcgcgatcccggcgcagatcctcgcctccggtgtcgcggtgccgtgg
gccgtcgaggcccagcggatcctcgcctccgagtggaacgtcaaggcggacgtctggtcg
gcgacctcctggaacgagctgcgccgcgaggccgtcgaggtggagcggcacaatctgctg
caccccgaggaggagcagcgcgtcccctatgtgacgcggaagctcagcagcgccgagggg
ccgttcgtggccgtctccgactggatgcggtccgtgcccgaccagatctcccgctgggtg
ccggggacctatcagtcgctcggcgcggacggcttcggcttcgcggacacgcggggtgcc
gcccgccgcttcttccacatcgacgcccagtcgatcgtggtcggcgtgctcaccgagctg
gcccgcgagggcaagatcgaccgctccgtcctgaagcaggcgatcgaccgctatcagctc
ctggacgtcgcggcggccgacccgggcgccgcagggggcgacgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (35)   

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