KEGG   Streptomyces noursei NK660: DC74_3061
Entry
DC74_3061         CDS       T03082                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
salu  Streptomyces noursei NK660
Pathway
salu00290  Valine, leucine and isoleucine biosynthesis
salu00620  Pyruvate metabolism
salu01100  Metabolic pathways
salu01110  Biosynthesis of secondary metabolites
salu01210  2-Oxocarboxylic acid metabolism
salu01230  Biosynthesis of amino acids
Module
salu_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:salu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    DC74_3061
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DC74_3061
Enzymes [BR:salu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     DC74_3061
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AIA03561
Position
complement(3442448..3444205)
AA seq 585 aa
MSQPVGRPTPITNATHAQTSSGMPIHKYRPFEAVDLSARTWPAKRITKAPRWLSTDLRDG
NQALIDPMSPARKREMFDLLVRLGYKEIEVGFPSSGETDFAFVRSIIEEGAIPDDVTISV
LTQAREELIERTVEALRGAPRATVHLYNATAPTFRRVVFRGSKEQVKQIAVDGTRLVMEY
ADKLLGDETAFGYQYSPEIFTDTELDFALEVCEAVMDVWQPEAGREIILNLPATVERSTP
STHADRFEWMSRNLSRREFVCLSTHPHNDRGTAVAAAELAVMAGADRVEGCLFGQGERTG
NVDLVTLGMNLFSQGVDPQIDFSQIDEIRRTSEYCNQMEVHPRHPYAGDLVYTAFSGSHQ
DAIKKGFDALEADAAAQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYV
LKNDHKLDLPRRMQIEFSRIIQEKTDAEGGEVTPKAIWDTFRDEYLPNPQNPWGRIQVRT
GQTTTDKDGVDTLTVEAEVDGVETVLTGSGNGPISAFFDALSGLGIDARLLDYQEHTMSE
GASAQAASYIECAIDGKVLWGIGIDANTTRASLKAVVSAVNRSAR
NT seq 1758 nt   +upstreamnt  +downstreamnt
atgtcgcagcctgtcggccgccccaccccgatcaccaacgccacccacgcccagacgtcg
tccgggatgccgatccacaagtaccgcccgttcgaggccgtggacctctccgcgcgcacc
tggccggcgaagcggatcaccaaggcgccccgttggctctccaccgacctgcgcgacggc
aaccaggcgctgatcgacccgatgtcgccggcccgcaagcgcgagatgttcgacctgctg
gtacgcctgggctacaaggagatcgaggtcggcttcccgtcgtccggcgagaccgacttc
gccttcgtccggtcgatcatcgaagagggcgcgatcccggacgacgtcaccatctcggtg
ctgacgcaggcccgggaggagctgatcgagcggaccgtcgaggcgctgcgcggcgccccc
cgtgccaccgtccacctctacaacgccaccgcccccaccttccgccgggtcgtcttccgc
ggctcgaaggagcaggtcaagcagatcgcggtggacggcacccggctggtgatggagtac
gccgacaagctgctgggcgacgagacggccttcggctaccagtacagcccggagatcttc
accgacaccgagctggacttcgcgctggaggtctgcgaggcggtgatggacgtctggcag
cccgaggcgggccgcgagatcatcctcaacctgccggccaccgtggagcgttcgaccccg
tccacgcacgccgaccgcttcgagtggatgagccgcaacctgagccggcgcgagttcgtc
tgcctgtccacgcacccgcacaacgaccgcggcacggccgtggccgccgccgaactggcc
gtgatggccggcgccgaccgcgtcgagggctgcctgttcggtcagggcgagcgcaccggc
aacgtcgacctggtgacgctgggcatgaacctcttctcgcagggcgtcgacccgcagatc
gacttctcgcagatcgacgagatccgccgcaccagcgagtactgcaaccagatggaggtc
cacccgcgccacccctacgcgggcgacctggtctacaccgccttctccggctcccaccag
gacgccatcaagaagggcttcgacgcgctggaggccgacgcggccgcccagggcaagacc
gtcgacgacatcgagtgggcggtgccgtacctgcccatcgaccccaaggacgtcggccgc
tcctacgaggccgtcatccgggtcaactcgcagtccggcaagggcggtatcgcctacgtc
ctgaagaacgaccacaagctggacctgccgcgccggatgcagatcgagttctcccggatc
atccaggagaagaccgacgccgagggcggcgaggtcaccccgaaggccatctgggacacc
ttccgggacgagtacctgcccaacccgcagaacccgtggggccgcatccaggtcaggacc
gggcagaccaccaccgacaaggacggcgtggacaccctcaccgtcgaggcggaggtggac
ggcgtcgagaccgtcctgacgggctccggcaacggtccgatctccgcgttcttcgacgcg
ctgtccggcctgggcatcgacgcccgcctgctggactaccaggagcacaccatgagcgag
ggcgcctccgcgcaggccgcctcgtacatcgagtgcgccatcgacggcaaggtgctgtgg
ggcatcggcatcgacgccaacaccacccgcgcctccctcaaggccgtggtctccgccgtc
aaccgctcggcgcgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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