KEGG   Streptomyces noursei NK660: DC74_4158
Entry
DC74_4158         CDS       T03082                                 
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-alpha chain
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
salu  Streptomyces noursei NK660
Pathway
salu00280  Valine, leucine and isoleucine degradation
salu00640  Propanoate metabolism
salu00785  Lipoic acid metabolism
salu01100  Metabolic pathways
salu01110  Biosynthesis of secondary metabolites
salu01210  2-Oxocarboxylic acid metabolism
Module
salu_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:salu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    DC74_4158
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    DC74_4158
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    DC74_4158
Enzymes [BR:salu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     DC74_4158
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: AIA04640
Position
complement(4733672..4734871)
AA seq 399 aa
MTVLEQPGSSRHTSDLAGPPPAWRPRVDPAPLLPDAEPYRLLGTDAAGRLDPGLLKRLYT
ELVRGRRYNTQATALTRQGRLAVYPSSTGQEACQVAAALALQEQDWLFPSYRDTLAAVAR
GLDPVQALTLLRGDWHTGYDPYEHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMV
GDGGTSEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLAKQSAAPTLAHKAVGYGMPGR
LVDGNDAPALHEVLTDAVRRAREGGGPTLVEAVTYRLEAHTNADDATRYRTDAEVESWRA
HDPIALLERALTDRALLDDAFATATRDGAERLAADLRERMHAEAPLAPMDLFDHVFTQQT
SQLRSQAAQLRAELDAEAEGAEAPESATGTVAPAQEARP
NT seq 1200 nt   +upstreamnt  +downstreamnt
atgacggttctcgagcagcccggcagcagcaggcacaccagtgaccttgccggcccgccg
cccgcctggcggccgcgcgtcgatcccgcgcccctcctacccgacgccgagccgtaccgc
ctcctgggcaccgacgccgccggccggctcgaccccggactgctgaagcggctctacacc
gagctggtgcgcggtcgccggtacaacacccaggccaccgccctcacccgccagggccgg
ctggcggtctacccctcgtccacgggccaggaagcctgccaggtcgccgcggcactcgcc
ctccaggagcaggactggctcttccccagttaccgcgacaccctcgccgccgtcgcccgc
ggcctcgatccggtgcaggccctgaccctcctgcggggcgactggcacaccggctacgac
ccgtacgagcaccgcatcgcccccctgtgcaccccgctcgccacccagctcccgcacgcc
gtgggcctggcgcacgccgcccgcctcaagggtgacgacgtggtcgccctggccatggtc
ggcgacggcggcacgagcgagggcgacttccacgaggcgctcaacttcgccgccgtctgg
caggcgccggtcgtcttcctcgtgcagaacaacggcttcgcgatctccgtgccgctcgcc
aagcagagcgccgcgccgaccctcgcccacaaggcggtcggctacggcatgcccggtcgc
ctggtggacggcaacgacgcccccgccctgcacgaggtcctcaccgacgcggtgcgccgg
gcccgtgagggcggcggccccacgctcgtcgaggccgtcacctaccgcctagaggcccac
accaacgccgacgacgccacccgctaccgcaccgacgccgaggtcgagagctggcgggcc
cacgacccgatagccctgctggagcgcgcgctgaccgaccgcgccctgctcgacgacgcg
ttcgccaccgccacccgcgacggagccgagcgcctcgccgccgacctccgggagcggatg
cacgccgaagcgccactggcgccgatggacctcttcgaccacgtcttcacccagcagacc
agccaattgcgctcccaggccgcccagttgcgcgccgagctggacgccgaggccgaaggg
gccgaagcacccgagtccgccacgggcaccgtggcgcccgcccaggaggccaggccatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (53)   

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