KEGG   Staphylococcus aureus subsp. aureus ST228/16035 (MRSA): SAI4T8_1002750
Entry
SAI4T8_1002750    CDS       T03146                                 
Name
(GenBank) Methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
sauq  Staphylococcus aureus subsp. aureus ST228/16035 (MRSA)
Pathway
sauq00270  Cysteine and methionine metabolism
sauq00450  Selenocompound metabolism
sauq00670  One carbon pool by folate
sauq01100  Metabolic pathways
sauq01110  Biosynthesis of secondary metabolites
sauq01120  Microbial metabolism in diverse environments
sauq01230  Biosynthesis of amino acids
Module
sauq_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sauq00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    SAI4T8_1002750
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    SAI4T8_1002750
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SAI4T8_1002750
Enzymes [BR:sauq01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     SAI4T8_1002750
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     SAI4T8_1002750
SSDB
Motif
Pfam: MTHFR S-methyl_trans DUF6506
Other DBs
NCBI-ProteinID: CCJ25975
UniProt: A0A7U7EX04
Position
complement(378709..379959)
AA seq 416 aa
MGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLI
REGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKV
QERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQY
YNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKG
LTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVKRLEKKIESGMSYFITQP
VYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQQFEAVKDD
KAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHKEAIL
NT seq 1251 nt   +upstreamnt  +downstreamnt
gtgggactcaattgtcatcatggtccgcaccatatgcaagagtctttcacacatattgaa
ttaccagagcacgcattcttatcttgttatccaaatgccagcttattagatattgaaaat
agtgaatttaagtatagtgacaatgcacaatatttcggtcaagttgctcaaaatctaatt
cgcgaaggtgttcgtttaattggtggttgctgtggtacaacgccagagcacatcaaattt
attaaagaatctattcagacacttaaacctgttaatgacaaaaaagttattccgatacca
acgaaagcacttttcaatccatctcaaaataaagttagacaatcattaacatctaaggtt
caagaacgtccaaccgttattatcgaattggatacaccgaaacatttagacacggataga
ttttttgaaaatatcgctaaacttgataaagctaatgtagatgcggtaacactcgcagat
aattcattggcaactgtcagaattagcaatattgctgctgctagcttaattaagcaatat
tacaatattgaaccactcgtacatattacatgtcgagaccgaaacttaatcggcttgcag
tcccatttacttggattatcgctcattggcgttaacgaaatattagccataactggtgat
ccttcaaaagttggtcacttaccaggtgcaaccaatgtctatgatgttaattctaaagga
ttaactgaactcgctctaagatttaatcaaggtattaacactgacggtgatgcgctgaag
aaacgtacacacttcaacatcgctggcgcctttaaccctaatgttcgtaaattagatggt
gccgtcaaaagattagagaaaaagatagaaagcggaatgtcttattttataacacaaccc
gtgtacagcaaagagaaaatcattgaaatttaccatgccactaagcacttgaacaaacca
tttttcataggcattatgcctatcgcaagttacaaaaacgcactctttttgcataatgaa
gtgccaggaatcaagatgtcagatgaaattttacaacaatttgaagcagttaaagatgat
aaagccaaaacacgagaactaagtcttaagctttcaaaggatttaatcgatactgttcat
gaatattttaatggtttatacattatcacaccgtttcaaaatgtcgaagattcattagaa
cttgcagcatactcaaaatctattactgctcacaaggaggcaatattatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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