KEGG   Sulfobacillus acidophilus TPY: TPY_2937
Entry
TPY_2937          CDS       T01576                                 
Symbol
mmuM
Name
(GenBank) bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
say  Sulfobacillus acidophilus TPY
Pathway
say00270  Cysteine and methionine metabolism
say00450  Selenocompound metabolism
say00670  One carbon pool by folate
say01100  Metabolic pathways
say01110  Biosynthesis of secondary metabolites
say01120  Microbial metabolism in diverse environments
say01230  Biosynthesis of amino acids
Module
say_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:say00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    TPY_2937 (mmuM)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    TPY_2937 (mmuM)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TPY_2937 (mmuM)
Enzymes [BR:say01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     TPY_2937 (mmuM)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     TPY_2937 (mmuM)
SSDB
Motif
Pfam: S-methyl_trans MTHFR
Other DBs
NCBI-ProteinID: AEJ41095
Position
complement(2716988..2718859)
AA seq 623 aa
MKPLAEALSHGLWLADGAIGTWFLSQGVEPHQLPLLPLDHPDLVIRCHLEYLQAGAQIIE
THSFSANRSKLAAMGWDGSVGELNRRAAQLARHARDIFGEPAYVLGSLGPLAVPVDSPIV
PGLDRAEAETVYREAVAGLLAGGVDGFLVETMSDLATVEAAVSAIRAESDLPIVVSFAFS
PLGTTLYGITPEAAVEAVMTLPGGPPAAIGANCGSGPSPLLDAVIRMAEKARTYQLPVVA
YPNAGEPALRDGHVHYPASPDYMATIAPALKAAGCAVIGGCCGTTPSHIRAIRQNMQGDL
HPQLTARPGWSLTEDVVPKSPDPEWSRPPRLVHELLAQQFVLSVELDPPRGPNLTRLVDA
ARQLEEEQVDVINVADSPMARVRLGALATARLIQERTRLATILHFTTRDRNLMGLQSDLL
GAFALGLTNILCLTGDPPGLGDYAHATAVYDLDSIGLTKVLAGFNQGLDALGQPLGSPTV
FSIGVGVNPTADPLEKEIERFRQKVAAGAHYAMSQPIYAPEQFYRFLDALGGPLPIPLIL
GIMPLVSYRQALYLHNEVPGITIPPEVLSRFESVQDGVHVGIELALELIQALRAGIHGIY
LVPSFNRVEPLVPLIREIRRLTR
NT seq 1872 nt   +upstreamnt  +downstreamnt
gtgaaaccgctggccgaggcgctgagccatggactttggctggctgacggcgcaatcgga
acctggtttttgtcccaaggggtagagccccaccaactgcccttgttgccgttggatcat
ccggatttggtcatccgctgccatctggaatatttgcaagccggtgcccagatcattgaa
acgcatagtttttcggctaaccggagcaaattggcggctatgggctgggacggatcggtc
ggggagttaaaccggcgggcggctcaactggcccgccacgcccgggatatttttggcgag
ccggcctatgtgctcggctcgctgggccctttggccgtcccggtggattccccgattgtg
ccggggcttgaccgggccgaggcggaaaccgtctatcgggaagcggtagcagggcttctg
gccggcggggtggacgggtttttggtggagacgatgtcggacttggcgacggttgaagcg
gcggtttcggccatccgcgccgaaagcgatttgccgatcgtggtctccttcgcgttctcc
ccgttgggcaccacactctatgggattacgccggaggctgccgtagaagccgtgatgacg
cttccgggcgggccgccggcggccatcggcgccaactgcggcagtggtccctccccgctc
ttggatgcggtcatccggatggcggaaaaggctcgtacgtatcagctgccggttgtggcc
tatccgaacgcgggggagccggctctacgggacggccatgtgcactatccggcgtctccg
gactacatggccacgattgcaccggcgttaaaggcggccggctgcgcggtgatcggcggc
tgttgcggcacgactccgagccatattcgggcgattcgacaaaacatgcaaggggacctg
catccccaattgacggcccggccgggttggagtctgacggaagatgtagtaccgaaaagc
ccggatccggaatggagccgcccgccacgcctcgtgcacgagctgttggcacagcagttt
gtgctgagcgtcgaattggatcccccgcgtggccctaatttaacgcgattagtggatgcg
gcccggcaactggaagaggaacaggtcgatgtcatcaatgtggccgattcgccgatggcc
cgggtacggttgggcgccttggccacagcccgtttaattcaagaacggacgcggctggcg
accattttacactttaccactcgcgatcgaaatctcatgggcctgcaaagtgatttatta
ggggcgtttgcactcgggttgaccaatattttgtgtttaaccggtgacccgccgggactc
ggcgactatgcgcacgccacggcggtttatgatttggattccattgggctcaccaaggtt
ttggccggctttaaccaagggctggatgccctggggcaacctctgggatcgccgacggtt
ttttcgattggcgtgggggtgaatcctacggcagatccgctagaaaaagaaatcgagcgc
tttcggcagaaagtggccgccggggctcattatgccatgtcgcaacccatctatgcgccc
gagcagttctatcgctttttggatgcgctcgggggtccgttgcccatcccgctgattttg
gggattatgcccttggtatcgtatcgacaagcgctatatttgcataacgaagtgccggga
atcacgattccgcccgaggtgctgagccgcttcgagtcggttcaagacggtgttcacgtc
gggatcgagctggcgttggaacttattcaagccttacgggccggaattcacgggatctat
ttggtaccgtcttttaatcgcgtcgaaccattggtgcctctgattcgggaaattcgacgg
ctcacccgataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (49)   

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