KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101040472
Entry
101040472         CDS       T04350                                 
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00140  Steroid hormone biosynthesis
sbq00980  Metabolism of xenobiotics by cytochrome P450
sbq01100  Metabolic pathways
sbq05204  Chemical carcinogenesis - DNA adducts
Module
sbq_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101040472 (HSD11B1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101040472 (HSD11B1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    101040472 (HSD11B1)
Enzymes [BR:sbq01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     101040472 (HSD11B1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR THF_DHG_CYH_C 2-Hacid_dh_C Pyr_redox_3 Pyr_redox_2 Shikimate_DH NAD_binding_2 AdoHcyase_NAD
Other DBs
NCBI-GeneID: 101040472
NCBI-ProteinID: XP_003930452
UniProt: A0A2K6V286
Position
Unknown
AA seq 291 aa
MAFMKTHLLPILGLFMAYYYYSAYEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNFFHDDIHHVRKSMEVNFLSYVVLTVAAMPMLKQSNGSIVIVSSVAGKVAYPMI
SAYSASKFALDGFFSSIRKEYLMSEVNVSITLCVLGLIDTDTAMKAVSGIIKMQAAPKEE
CALEIIKGGVLRQEEVYYDRSLWTTLLLRNPSRKILEFLRSTSYSTDGLIN
NT seq 876 nt   +upstreamnt  +downstreamnt
atggcttttatgaaaacacatctactccccattctggggctcttcatggcctactactac
tattctgcatatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaagggattggaagagaaatggcttatcatctggcgaagatgggagcccat
gtggtggtgacagcgaggtcaaaagaaactctacagaaggtggtatcccactgcctggaa
cttggagcagcctcagcgcactatattgctggcaccatggaagacatgaccttcgcagag
caatttgttgcccaagcaggaaagctcatgggaggactagacatgctcatcctcaaccac
atcaccaacacttctttgaatttttttcacgatgacattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttatgtggtcctgactgtggctgccatgcccatgctgaagcag
agcaatggaagcattgttatcgtctcctctgtggctggaaaagtggcttatccaatgatt
tctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tatttaatgtctgaggtcaatgtgtcaatcactctctgtgttctcggcctcatagacaca
gacacagccatgaaggcagtttctgggataatcaaaatgcaagcagctccaaaggaggaa
tgtgccctggagatcatcaaagggggagttctgcgccaagaggaagtgtattatgaccgc
tcactctggaccactctcctgctgagaaatccatccaggaagatcctggaatttctccgt
tcaacgagttatagtacagatggattgataaactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (44)   

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