KEGG   Saccharomyces cerevisiae (budding yeast): YER014W
Entry
YER014W           CDS       T00005                                 
Symbol
HEM14
Name
(RefSeq) oxygen-dependent protoporphyrinogen oxidase
  KO
K00231  protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00860  Porphyrin metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01240  Biosynthesis of cofactors
Module
sce_M00868  Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    YER014W (HEM14)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.3  With oxygen as acceptor
    1.3.3.4  protoporphyrinogen oxidase
     YER014W (HEM14)
    1.3.3.15  coproporphyrinogen III oxidase (coproporphyrin-forming)
     YER014W (HEM14)
SSDB
Motif
Pfam: NAD_binding_8 Amino_oxidase NAD_binding_9 Thi4 DAO Pyr_redox Pyr_redox_2 Mqo
Other DBs
NCBI-GeneID: 856733
NCBI-ProteinID: NP_010930
SGD: S000000816
UniProt: P40012
Position
V:182600..184219
AA seq 539 aa
MLLPLTKLKPRAKVAVVGGGVSGLCFTYFLSKLRPDVEITLFESQNRTGGWIYSCNTRDM
SGNPIMLEKGPRTLRGVSDGTVLIMDTLKDLGKEAVIQSIDKGCIADKKFLLDPSDKLVQ
VPNSISTTVKFLLNPLGKGLITGMMGEWFRKKSPHPGQDESVESICDRRFGNNYISNNMI
SALLRGIYGDDVSLLSAKRTFKKIYYNELKHGSNTQAMIDNMRGKSRSKKTENLHQSLTG
CLNDYSNAFGKDRSKLLDLSNTLKKYPMLGLAGGLETFPKIVRNALNEFKNVKIVTGNPV
TQIMKRPANETTIGLKAKSGDQYETFDHLRLTITPPKIAKLLPKDQNSLSKLLDEIQSNT
IILVNYYLPNKDVIDADLQGFGYLVPKSNKNPGKLLGVIFDSVIERNFKPLFDKLSTNPN
ALNKYTKVTAMIGGCMLNEHGVPVVPSREVTINAVKDALNNHLGISNKDLEAGQWEFTIA
DRCLPRFHVGYDAWQERAERKLQESYGQTVSVGGMGFSRSPGVPDVIVDGFNDALQLSK
NT seq 1620 nt   +upstreamnt  +downstreamnt
atgttattaccattaacaaagctaaaaccgagagcaaaagttgctgttgtagggggtggc
gtttctggactatgttttacttattttttaagcaagttgagaccggatgttgaaatcaca
ctgttcgaatcgcagaacagaactgggggttggatatattcttgtaacacaagagatatg
agtgggaacccaattatgttggagaagggacccagaacattgaggggcgtatcagacggg
accgttctgattatggatacccttaaagacttgggcaaggaagcagttattcaaagcatt
gataaaggttgcattgcagacaaaaagtttctactagaccccagtgataaactcgtgcag
gttcctaattcgatatctacaacagtaaaatttctgctgaatccgttgggaaaaggactc
atcacgggtatgatgggagaatggttcagaaaaaaatctccacatcctggccaagacgaa
agtgtcgaatccatttgtgacagaaggtttgggaataactacatatcaaacaatatgatc
agtgccttactaagaggtatctatggggatgacgtttccctattaagtgccaagagaacg
tttaagaaaatatactacaatgaactaaagcacggatctaacacacaagctatgattgat
aatatgcgcggaaagtcaagaagtaaaaaaactgagaacctgcaccaatctttaactggc
tgccttaacgactactcaaatgcgtttggaaaagacaggtcaaagttattagacttatcc
aacacgctaaagaaatatcccatgttgggtcttgctgggggactagaaacgtttcccaag
atagtcagaaatgctttgaacgaatttaaaaacgtcaaaatagttactgggaacccggtt
acgcaaataatgaaacgccctgctaacgaaacgacaatcggattgaaagcgaaatctggc
gaccaatacgaaacatttgaccatttaagacttacgataacacctcccaaaatcgctaaa
ttgctaccgaaggatcaaaattcattatccaagttattagatgagatacaatcaaacaca
ataattttagttaattattatttgccaaacaaagatgtaatagatgccgatctacaaggc
tttggatacttggttcccaaatccaataagaatccagggaaattgcttggtgtaattttc
gattctgttatcgaaaggaatttcaaaccactttttgacaaactctccacaaacccaaac
gccctcaacaaatatacaaaagtgactgcgatgataggaggttgtatgctcaatgaacac
ggtgttcctgtagtgccatccagggaggtaaccattaatgcagtcaaagatgcgctgaac
aaccacctcggcatcagtaacaaggatctggaagctggtcagtgggaattcactatcgcc
gatagatgtctgccaagatttcatgtaggttatgacgcatggcaagaaagagctgaaagg
aagttgcaagaatcttacggccaaacagtttctgtggggggaatgggattttctagaagt
cccggtgtccctgacgttattgtagacggctttaacgacgccttacagctaagcaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (4)   
   KEGG MODULE (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (50)   

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