KEGG   Saccharomyces cerevisiae (budding yeast): YGL125W
Entry
YGL125W           CDS       T00005                                 
Symbol
MET13, MET11, MRPL45
Name
(RefSeq) methylenetetrahydrofolate reductase (NAD(P)H) MET13
  KO
K25004  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00670  One carbon pool by folate
sce01100  Metabolic pathways
sce04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    YGL125W (MET13)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    YGL125W (MET13)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.53  methylenetetrahydrofolate reductase (NADPH)
     YGL125W (MET13)
SSDB
Motif
Pfam: MTHFR MTHFR_C DUF6919
Other DBs
NCBI-GeneID: 852752
NCBI-ProteinID: NP_011390
SGD: S000003093
UniProt: P53128
Position
VII:272520..274322
AA seq 600 aa
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
NT seq 1803 nt   +upstreamnt  +downstreamnt
atgaagatcacagaaaaattagagcaacatagacagacctctggcaagcccacttactca
ttcgagtacttcgtcccgaagactacacaaggtgtacagaacctgtatgaccggatggac
cggatgtacgaggcttctttgccccaatttattgacatcacctggaatgcaggcggtgga
cggttgtcacatctgtccacggacttggttgcgacagcgcagtctgtgcttggtttggaa
acgtgcatgcaccttacctgcaccaatatgcccatttcgatgattgacgacgctttagaa
aacgcttatcactccggttgccagaacatcctagcgctgagaggagatcctcctagggac
gcagaaaactggactcccgttgaaggtggcttccagtatgccaaggacttgattaagtat
atcaagtccaagtacggtgaccatttcgctatcggcgttgccggctacccggagtgccat
ccggagttgcctaacaaagacgtgaagcttgatctcgagtatttgaagcagaagatcgac
gccggcggcgacttcatcatcactcagatgttttacgatgttgataatttcatcaactgg
tgttcccaagttagagctgcgggcatggacgtgcccattattcccgggatcatgccgatc
actacctacgcggccttcttgagaagggcccaatggggccaaatctccatccctcaacat
ttctcgtcccgattggatcctatcaaggacgatgacgagttggtccgtgatatcggaact
aacttgatcgtggaaatgtgtcaaaaattgctcgacagtggttacgtttctcacttgcac
atctacaccatgaacttggaaaaagcgcctctcatgattctggaaagattgaacattcta
cctacggaatcagagttcaatgcacatccattggccgtgttgccatggagaaaatctttg
aatccaaagcgtaaaaacgaggaagtcagacctatcttctggaagagaagaccttactcc
tatgtcgcaagaacctctcaatgggccgtggacgaattccccaacggtagattcggtgat
tcgtcttctcctgcgttcggtgacttggatctgtgtggttcagacttgatcaggcaatca
gcgaacaaatgtctcgaattatggtccacccctacttccatcaacgacgtcgccttcttg
gtcatcaactacttgaatggaaacttgaagtgtttaccttggagtgatatccccatcaat
gatgaaataaatccaatcaaagcacacttgattgagctgaaccagcattctatcatcact
ataaactctcaacctcaagtcaacggcattaggtccaatgacaaaattcatggttgggga
cccaaggatggttacgtttaccagaagcaatatttggaatttatgttgcccaagactaag
ttgcccaagttgattgacaccttgaaaaacaatgagttcttgacctacttcgccatcgac
tctcaaggtgacctgctaagtaatcatccagacaactccaagtccaacgctgtgacttgg
ggtattttccccggcagagaaattcttcaacctaccattgtcgagaaaatttcgttctta
gcgtggaaggaggagttctatcatatcttgaatgaatggaaactaaacatgaataaatac
gataaaccgcatagtgcccaattcattcagtccttgattgacgattactgcttggtcaat
attgttgacaatgactacatttctccagatgatcaaatccattccatcctactaagccta
taa

  All links  
Gene (24)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (31)   

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