KEGG   Saccharomyces cerevisiae (budding yeast): YJL130C
Entry
YJL130C           CDS       T00005                                 
Symbol
URA2
Name
(RefSeq) bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase
  KO
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00240  Pyrimidine metabolism
sce00250  Alanine, aspartate and glutamate metabolism
sce01100  Metabolic pathways
sce01240  Biosynthesis of cofactors
Module
sce_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    YJL130C (URA2)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    YJL130C (URA2)
Enzymes [BR:sce01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     YJL130C (URA2)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     YJL130C (URA2)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS Dala_Dala_lig_C ATP-grasp ATPgrasp_Ter ATP-grasp_3 RimK Peptidase_C26 TrkA_N
Other DBs
NCBI-GeneID: 853311
NCBI-ProteinID: NP_012405
SGD: S000003666
UniProt: P07259
Position
X:complement(165723..172367)
AA seq 2214 aa
MATIAPTAPITPPMESTGDRLVTLELKDGTVLQGYSFGAEKSVAGELVFQTGMVGYPESV
TDPSYEGQILVITYPLVGNYGVPDMHLRDELVEELPRYFESNRIHIAGLVISHYTDEYSH
YLAKSSLGKWLQNEGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRS
AFDVPEWVDPNVQNLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQ
IRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEAKKTPVFG
ICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKP
LFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVKEFKYTQVLKPIA
FPGGLLEDNVKAHPRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINP
NIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMKDEFEAL
GVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAA
YALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCN
MENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKD
YCIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYC
VVKMPRWDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLD
IDIDYELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFG
TKEELPSLVLRQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAY
TNYLYMTYNADSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVN
YNPETVSTDYDEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVK
ILGTSPDMIDSAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVL
SGAAMNTVYSKNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSE
HVENAGVHSGDATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVI
ECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLA
GADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSV
QKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYIN
LPSANRFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQT
SHRTITLPGLINIATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDV
ASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELKNKITAVAELL
NQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDV
NIYSLFIAQDDYPEAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMGI
KDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQDSVVEIDLDYSFRRNKRWSPFN
KDMNGGIERVVYNGETLVLSGELVSPGAKGKCIVNPSPASITASAELQSTSAKRRFSITE
EAIADNLDAAEDAIPEQPLEQKLMSSRPPRELVAPGAIQNLIRSNNPFRGRHILSIKQFK
RSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFIAAMERLGGRIVN
VNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVPIINGGNGSREHP
TQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRINLVSPPELRLPE
GLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTYIVDNKIL
AHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMGVDM
NT seq 6645 nt   +upstreamnt  +downstreamnt
atggccactattgctcccactgctccaatcacccctccaatggaatctacgggtgaccgt
ctggttacgttggaacttaaggacggcacggtcttacaaggttattcatttggtgctgag
aaatccgtcgctggtgaattagttttccaaactggtatggttggttatcctgaatctgtg
accgatccatcttatgaaggccagatcttagtcatcacttacccattggtaggcaattat
ggtgtcccagatatgcacttgagagatgaattggtcgaagaattgccaagatattttgaa
agtaatagaatccatattgccggtttagttatttctcactataccgacgagtactctcat
tatcttgctaaatcttccttaggtaaatggttacaaaatgaagggatcccagctgtttat
ggtgttgatacaagatcattgaccaagcatttgagagatgcaggttcaatgttgggtagg
ttgtctttggaaaaaagcggctctgacagaaccatctccagatcttcctcttggagaagt
gcgtttgatgttcctgaatgggtggatccaaatgttcaaaacctagtttctaaggtctcc
atcaatgaacctaaattgtacgttcctccagcagacaataagcacatcgaattgcaaacc
ggacccgatggtaaagttttaaggattctagccattgacgtgggtatgaaatacaatcaa
attcgttgttttatcaaaaggggtgtagaattgaaagttgttccatggaactacgatttc
actaaagaagattatgatggtctgtttatttcaaatggtccaggtgatccatctgttcta
gatgatctatctcaaagattgtcaaatgtcctggaggctaaaaagacgccagtattcggt
atttgtctcggtcatcaattgatagcaagagctgccggtgcatccaccctaaaactaaaa
tttggtaaccgtggtcataacataccttgtacatcaactataagtggtcgttgttacata
acatctcaaaaccatgggttcgctgtggatgttgacactctaacttccggatggaagcca
ttgtttgttaacgcgaatgatgactctaacgaaggtatctatcattctgaattaccttat
ttttccgtccaattccatccagaatccacacctggcccaagagatacagaattcttgttt
gacgtttttatccaagcagttaaagaattcaagtatacacaagtgttgaaaccaatcgct
ttcccaggtggcctattagaggataacgttaaggcacaccctagaatcgaagcgaagaag
gttctagttctcggttctggtggtttgtccatcggtcaagctggtgaatttgactactct
ggttctcaagccatcaaagctttgaaagaagaaggtatctatacaattttaattaatcca
aacattgctaccatccaaacttcgaaagggttggctgataaggtttattttgttcctgtt
actgcagagttcgtgagaaaagttattttacatgaaaggccggacgccatttatgtgaca
tttggtggacaaactgctttatctgttggtatagccatgaaagatgaatttgaggcgtta
ggagttaaagtattgggtactccaatcgatactattattaccacggaagaccgtgaactc
ttcagtaatgccattgacgaaattaatgaaaaatgtgcgaaatctcaagctgctaattca
gtggacgaggcattggccgctgtcaaggagatcggtttcccagttattgtacgtgctgca
tatgcattgggaggtttaggttccggtttcgctaataatgaaaaagaattggttgatcta
tgtaatgttgcattttcatcctcacctcaagttttagtcgagaaatctatgaaaggttgg
aaagaagtcgaatatgaagttgttcgtgatgcttttgacaactgtattactgtttgtaat
atggaaaattttgatccactaggtattcacaccggtgattccatcgttgtagccccatct
caaactttatctgatgaagattacaatatgttaagaactactgctgttaatgttattaga
cacttaggtgttgttggtgaatgtaatatccaatatgctttaaatcccgtttctaaggat
tattgcatcattgaagttaatgcgcgtttgtcacgttcctctgctttagcttctaaggct
actggttacccattggcctacactgcggctaagttaggtttgaatatcccattaaatgaa
gttaagaattccgtcacaaaatccacatgtgcttgttttgaaccttctctagactactgt
gttgtcaaaatgccaagatgggatttgaagaagttcaccagagtttctaccgaattatct
tcatcaatgaaatctgttggtgaagttatgagcatcggtagaaccttcgaagaagctatt
caaaaagctatcagatccacagaatatgctaacctcggattcaatgagacagatctagat
atcgacattgattacgagttgaacaaccctacggatatgcgtgtcttcgccattgcaaat
gcttttgctaagaagggatattctgttgataaagtctgggaaatgactagaattgataag
tggtttttaaacaaactgcacgatttggtccaatttgctgagaaaattagttcatttggt
actaaagaggaattaccttccttagttttaagacaggctaagcagttaggttttgatgac
agacagattgcaagatttttggattccaacgaagttgccatccgtagattaagaaaagaa
tatggaattacaccatttgtcaaacaaattgatacagttgccgctgaattccccgcttac
acgaactatttatacatgacatacaatgctgactcacacgatttatcctttgatgaccac
ggtgttatggtcttgggttctggtgtttaccgtatcggttcttctgtcgaatttgattgg
tgtgctgttactgcagttagaacattacgtgccaacaatatcaaaactatcatggtcaac
tataatccagaaactgtttccacagattatgatgaggctgatagactatactttgaaacc
atcaaccttgaaagagttttggatatttacgagattgaaaactcaagcggtgttgtcgta
tcaatgggtggtcaaacttccaacaacatcgccatgactttacatcgtgaaaatgtaaag
attcttggtacatcccctgacatgattgattctgctgaaaaccgttacaagttctctcgt
atgttggatcaaattggtgttgaccaaccagcttggaaagaattgacatccatggacgaa
gctgaatcttttgccgaaaaggtgggttatccagttttggtacgtccatcttatgtgtta
tccggtgccgccatgaatactgtttattctaaaaacgatttggaatcctacttaaaccaa
gccgtcgaagtttcacgtgattatcctgttgttatcactaaatatattgaaaacgcaaag
gagattgaaatggatgcagttgcaagaaatggtgaattggttatgcatgttgtctctgag
catgttgaaaatgcaggtgtccactcgggtgatgcaacattaatcgttccacctcaagat
ttggctcctgaaactgtggatagaattgttgtcgccactgctaaaattggtaaggctttg
aaaattacaggtccatacaacatccaattcattgcaaaggacaatgaaatcaaggtcata
gaatgtaatgttcgtgcttcgagatctttcccattcatttcaaaggttgttggcgtcaat
ctgattgaattggcaacaaaggccataatgggtttgcctttgacgccttatcctgttgaa
aaattaccagatgattatgtcgccgttaaagtaccacaattctctttcccacgtttagca
ggagctgatccagtcttaggtgttgaaatggcctctactggtgaagtcgctacttttggc
cactcgaagtatgaagcatacttaaagtctttgttggcaaccggcttcaaacttccaaag
aagaatattttattgtctattggttcttacaaggaaaaacaagaattgctttcttccgta
caaaaactatacaacatgggatataaattatttgcaacatcaggtactgctgacttttta
tctgaacatggtattgccgtccaatatctggaggttttaaacaaggatgatgatgatcaa
aaatcagaatactcacttactcaacatttggctaataatgaaattgacctttacatcaac
ttgccttctgccaacaggttccgtcgtcctgcatcctatgtttcaaaggggtataaaaca
cgtcgtttggctgtcgattattcggttccgttggttactaacgttaaatgtgcaaaattg
ttgattgaagccatttcaagaaatatcactttagatgtttctgaacgtgatgcacaaact
tcccacagaactattaccttacctggtttaatcaatatcgcaacttatgttccgaatgca
tcccatgttatcaaaggcccagctgaactgaaggagaccacacgtctatttttggaatcc
ggttttacatactgtcaattgatgcccagatccatcagcggacctgttattactgacgtt
gcatccttgaaggccgcaaactctgtttcccaagattcatcttacactgacttttctttc
actattgctggtacagcacacaatgctcatagtgttacgcaatctgctagcaaagtgaca
gcattgtttttgcccctacgtgaattaaagaacaagatcacagcagtagctgaacttctg
aatcagtggccaactgaaaagcaagtgattgcagaagctaaaactgcagatttggcatcg
gttttattgttaacctcccttcaaaacagatctattcacattactggtgtttcgaataag
gaagatttagctttgatcatgacggtcaaggcaaaagaccctagagtgacttgtgatgtc
aatatttattctttgtttattgcccaagatgactatccggaggcagttttcttgcctact
aaggaagatcaagagtttttctggaacaaccttgatagtatcgatgctttctctgtcggt
gctcttcctgtcgccttggcaaatgtcacaggtaacaaggttgatgttggtatgggtatc
aaagattcattaccactattgttggctgctgttgaagaaggtaaattaaccattgatgat
atcgtccttcgtctgcatgacaatcccgctaaaattttcaacatccctactcaggactca
gttgtcgaaattgatttggattattctttcagacgtaataagagatggtcaccattcaac
aaagatatgaacggtggtattgagcgtgttgtctataatggcgaaacattagttttgagc
ggtgaattagtttcaccaggcgccaaaggaaaatgcattgttaatccaagtccagcttcc
ataactgcttccgcagagctccaatctactagtgctaaaagaaggttctcgatcacggaa
gaagcaatcgctgataatttagatgccgcggaggatgcaattccagaacagcctttggaa
caaaaattgatgtcttcaaggccaccaagagaacttgttgctccaggcgccatccagaat
ttgatccgtagtaacaatccattccgcggaagacatatattgtctatcaaacaattcaaa
cgttctgatttccatgtgttgtttgctgttgcacaagaactaagggcagctgtcgcaaga
gaaggtgtcttagatttaatgaaaggccacgttattactacaattttctttgaaccatct
actcgtacttgttcttcattcattgctgctatggaacgtttgggtggtagaattgtaaat
gttaatccattggtgtcttctgtcaagaaaggtgaaacccttcaagatactatcagaact
ttggcttgttacagtgatgccattgtcatgcgtcattcagaagaaatgtctgttcatatc
gccgctaaatattctcctgttccaattattaatggtggtaatggttctcgcgagcatcct
acgcaggccttcttggatttgtttacgattcgtgaagaaatcggtactgttaatggtatt
actgttactttcatgggtgatctcaaacatggtagaaccgtacattcattgtgtcgtttg
ttaatgcactatcaagtcagaattaatcttgtttctcctccggaattgaggttaccagaa
ggattaagagaagagctaagaaaagctggcttacttggtgttgagagcattgaattaacc
cctcatatcatctcaaagaccgatgttctgtattgtacaagggtccaagaagaaagattc
aatagccctgaagaatatgcacgtctgaaggatacttatatcgtggacaacaagatcttg
gcacacgccaaagaaaatatggctatcatgcatccattgcctcgtgtaaatgaaatcaaa
gaggaagtggactacgatcatcgtgctgcttacttcagacaaatgaagtatggtttgttc
gtcagaatggctttgttggccatggtcatgggtgttgatatgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (62)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (57)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (109)   

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