KEGG   Streptomyces cyaneogriseus: TU94_23250
Entry
TU94_23250        CDS       T03687                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
scw  Streptomyces cyaneogriseus
Pathway
scw00290  Valine, leucine and isoleucine biosynthesis
scw00770  Pantothenate and CoA biosynthesis
scw01100  Metabolic pathways
scw01110  Biosynthesis of secondary metabolites
scw01210  2-Oxocarboxylic acid metabolism
scw01230  Biosynthesis of amino acids
Module
scw_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
scw_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:scw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TU94_23250
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    TU94_23250
Enzymes [BR:scw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     TU94_23250
SSDB
Motif
Pfam: IlvN IlvC F420_oxidored NAD_binding_2 2-Hacid_dh_C AdoHcyase_NAD PDH_N Rossmann-like NAD_Gly3P_dh_N ApbA NAD_binding_7 GFO_IDH_MocA CoA_binding
Other DBs
NCBI-ProteinID: AJP03952
UniProt: A0A0C5FV81
Position
5522186..5523184
AA seq 332 aa
MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSRAKAEEQ
GLRVVTPAEAAAEADVIMILVPDPIQAQVYEESIAPNLKDGDALFFGHGFNIRFGFIKPP
AGVDVCMVAPKGPGHLVRRQYEEGRGVPCIVAVEQDATGNGFALALSYAKGIGGTRAGVI
KTTFTEETETDLFGEQAVLCGGAAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMY
EGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGSFARTWMDEYHGGLK
KYNEYKQQDSEHLLETTGKELRKLMSWVNDEA
NT seq 999 nt   +upstreamnt  +downstreamnt
gtggccgagctgttctacgacgccgacgccgacctgtccatcatccagggccgcaaggtc
gcggtcatcgggtacggcagccagggccacgcccacgccctgtcgctgcgcgactccggc
gtcgacgtgcgcgtcggtctgcacgagggctccaagtccagggccaaggccgaggagcag
ggcctgcgcgtggtgaccccggccgaggccgccgccgaggccgacgtcatcatgatcctg
gtcccggacccgatccaggcccaggtctacgaggagtccatcgccccgaacctgaaggac
ggcgacgccctcttcttcggccacggcttcaacatccgcttcggcttcatcaagcccccg
gccggcgtggacgtctgcatggtcgccccgaagggcccgggccacctggtccgccgccag
tacgaggaaggccgcggcgtgccctgcatcgtcgccgtcgagcaggacgccaccggcaac
ggcttcgcgctggccctgtcgtacgccaagggcatcggcggcacccgcgccggcgtgatc
aagaccaccttcaccgaggagaccgagaccgacctcttcggcgagcaggccgtgctgtgc
ggtggcgccgccgcgctggtgaaggcgggcttcgagacgctgaccgaggccggctaccag
ccggagatcgcgtacttcgagtgcctgcacgagctgaagctgatcgtggacctcatgtac
gagggcggcctggagaagatgcgctggtcgatctccgagaccgccgagtggggcgactac
gtcaccggcccgcgcatcatcaccgacgcgaccaaggccgagatgaagaaggttctcgcc
gagatccaggacggctcgttcgcccggacctggatggacgagtaccacggcggtctgaag
aagtacaacgagtacaagcagcaggactccgagcacctgctggagaccaccggcaaggag
ctgcgcaagctcatgagctgggtgaacgacgaggcgtga

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