KEGG   Seriola dumerili (greater amberjack): 111222523
Entry
111222523         CDS       T05606                                 
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
  KO
K08844  leucine-rich repeat kinase 2 [EC:2.7.11.1]
Organism
sdu  Seriola dumerili (greater amberjack)
Brite
KEGG Orthology (KO) [BR:sdu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sdu01001]
    111222523 (lrrk2)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sdu04131]
    111222523 (lrrk2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sdu04147]
    111222523 (lrrk2)
Enzymes [BR:sdu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     111222523 (lrrk2)
Protein kinases [BR:sdu01001]
 Serine/threonine kinases: TKL group
  LRRK family
   111222523 (lrrk2)
Membrane trafficking [BR:sdu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    111222523 (lrrk2)
Exosome [BR:sdu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   111222523 (lrrk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr LRR_8 LRR_4 Roc COR Ras LRR_1 Ank_2 Ank_3 Arf LRR_9 NACHT AAA_22 nSTAND3 Viral_helicase1 AAA_16 PduV-EutP Ank_4 MDM10 Septin cobW ATP_bind_1 G-alpha T2SSE MMR_HSR1 Ank_5 AAA_7 Gtr1_RagA ABC_tran DLIC LRR_6 AAA_18 GTP_EFTU MobB SRPRB SRP54
Other DBs
NCBI-GeneID: 111222523
NCBI-ProteinID: XP_022602006
Position
Unknown
AA seq 2546 aa
MVNKEELEERLRKLLVRLRTPQEDRQLCTLIQIIQDLLFLAHTDYAAELFEDKDVHVPLM
VMLSSYISSRGVQQVGWSLLCRLIEICPGTLDQLTRPLQAAKEWEVLGVHQQILKVLSQY
SADCRVTMVGLRALALLLRSDMIPLLVLEEEEDVFGLVVHAMKTFPTSEEVQLQGCRALQ
FLLESVSDDHLMEFVENRDHVVVLAALQRFPDSSELLLQAMKVLLPLARPGSNVEMLMSG
GARCYSVIIAAMDAFPDVEELQETACCLFMRFTSESYYNILVLNGVQRVAVRACQTFPNN
AALQAAALSCLADLTATIVQNKAVAEQGLEEGEAEENRGKEEVEDMGLGWMEACCAALEL
HAAEPAVQEAASWAIHNLLLHGAAVHQSEDEQDERTPVHRQLMAAMLLHSSSPSVFKAAT
SAIATLITHNGKMRSLLLSSGLHVNLVEMMKRHSASAEVSISACKLLKLLFQGRSASLDD
LNMAMSQILSTMKVHNFQPEVQLEALQASLVFLCPDRSLREHGTSVADPDMADVSLKVLK
NQCVVEGAHTLYLEVLNRFISSPIIQRCGLKVLSALADCSGAVDLLCQQGAIDTVLHTLQ
MFPQEREIHYWGLTLLNYLVTKKKLSRMIVPVLASVVVVSLIQYREDSEMLLKCFQVALR
MLDACSGAAAELQREDFDRQIFQHLRDETPDQSNSPLRRSVCLALSKMWCDPELHYSMLE
KACKDGDTTMAECLIELGADINRKTKTESLIYQVCERGGPLELVELLLSRGAHEQHLRRA
LAVSVKRGDGPTVIQLLGRLGLDLNNSALCLGGFRLGRLDAAWLSPLLAERGRAHSLRYN
SSKGMSLARYIQSLQKSKSVSGPPRSMADPCLTSGYISDESDDSSFSFVSMDDSLFFNDD
MESDGSDSLPGVLSQKPHNNSTEELRGGSFKRKQGRRRHASAESGQTESEHSESVHRRYG
RTGSTHKVFGSSESSAPLPKERERIRLLDLSGNELDSLSCLMDDSLVQQQLGYLLRLDLC
NNSLLEFPSALCQSLYSLTRLDLQGNQLRSLPVELLSLPSLSTLNVSRNCVGPLLTFDPA
VTCPSLRQLNLSFNEITAFPQELGRAMDQLEELFMEGNSITELCTPLCLPEIKLLDVSKN
GVENISPDFLTSCPKLETFSASMNKICSLSHLPSKITTLKLANNSFTYVSEAILDLTNLR
SVDMRTNNIAVLPGPGFWASSNLRELMFSKNCIASLDLSGPVYKWTRLEKLHLSGNKLSE
IPPQIGLLEGLTSLDMSHNANLRSFPDEMGKLGRLWDLPLDGLKLQLDLKLIGSKTKDIV
RFLQQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKLKRSQLNSKTAAVGIDVRDWTIR
ERDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNLSKGASQVDALKPWLFNIKAV
APLSPVILVGTHTDVSDELQLQACLTKIKEELLNHQGFPAITDYHMVSVCEDSDAMARLR
KAIAREVASFRIQGQPVMGQLVPDSYVELERRVVVERARVPSEFPVIRHRELLQLIQESQ
LQLEEAELPHAVHFLSEAGVLLHFDDPALQLQELYFIDPQWLCNIISQKLKLKSCGLWEH
PKGVVQRSVVEKFLFETKCFPKSHLTQFFKLLEKFQIALPFGEEQLLVPSNLSKHRPVIE
LPHSENSEVIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGREKVVRPNRIYWRRGIYLS
WSPEAYCLVEAASVEENPSSFVRITVPSSRRGRVLMGQVVDHVDSLLEEWFPGLLNTDMH
GSGEALLKKWALYSFEDGQEWSKILLEDLFTYFDNDFLLVNPEDPRCTLPISQIAPDLVL
SDQPAGTILDSEELDVDMSKENRLGDGGFGTVYRGVYKNEEVAVKIFNKHASELYIYRLL
RQELAVLGRLRHPSLVGLLAAGSTPQVLVMELALRGSLDSLFEHENGSLNWKLQHRIALQ
VADGLRYLHSAMIIYRDLKPHNVLLFNLKTNSEIIAKITDYGIAQYCCSMGVRSSEGTPG
FRAPEVARGNVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEVAVQGKLPDPVE
HYGCSPWPGFQTLMKDCLRESPQDRPTSAQVFDRLNSGEMLCLMKELVVPRAFNAECLTM
SSASSDSPFSSHRAWLGGGSSTSSHRVGSITAVDLDTNAVMTQDIDTSPVLCLVTVQIPN
EACDWLVAGTQSGSLVVISTQDMSTWHHLQSVTDAVTSLYFHVHPRRTQRKNYLLVGTAN
GLLTVYEDSVLKQEKGQPVKTVTVGNVSTPVMCLGQSLHSLDGRSVWAGCGTRILSFTAE
YDVCRTIDTRPNLFFQQQRSLAGESCVLRMVVDKYVYLNKAGTPTVEVWDKRSERMVDCI
DCAHIIRHGSGCRGRQGSEAELPTEAAPSWARVKALLVQTAAALWVGTRGGHLLLLELSK
HQTLQVIGPRCDSIRCIASALIETLNWKNVVLTLGRRLPQDKNQFDEESVLMAWNSTLPM
EVKDLNRHCEKREQIAAKMREQLHHS
NT seq 7641 nt   +upstreamnt  +downstreamnt
atggttaacaaggaggaattggaggaaaggctgaggaaacttctggtgaggctgagaacc
cctcaagaagacagacagctgtgcacactgatccagatcatccaggatctgcttttcctg
gcacacaccgactatgcagctgaactgttcgaagacaaagatgtccatgtgcctctcatg
gtgatgctgtcgtcctacatcagcagcagaggagttcagcaggtgggctggtcactgctg
tgtcggctgattgaaatatgccccggtacgctggaccagctaacgagacctctgcaggca
gccaaggagtgggaggtactgggagtgcaccagcagatcctgaaggtgctgtctcagtac
agcgcagactgcagagtgaccatggtgggactacgtgccctggcgctcctgctcagatca
gacatgattcccctgctggtgctggaggaggaggaggatgtgtttggcctggtggtgcac
gcgatgaagacgttcccgaccagtgaagaagtgcagctccaaggatgcagagctctgcag
ttcctcctggagagcgtgagcgatgaccacctcatggagtttgtggagaaccgggaccat
gttgtggtgttggcggcgctccagaggttcccggacagctccgagctgctgctgcaggcc
atgaaagtgctgctgccactggctcgccccggcagtaacgtggagatgctgatgtcagga
ggcgcccggtgctacagcgtgatcatcgccgccatggacgccttccccgacgtggaggag
ctgcaggagacggcctgctgcctgttcatgaggtttacatcagagagttactacaacatc
ctggtgctgaacggcgtccagagagttgcagtgagagcctgtcagactttccccaacaac
gccgcgctgcaagcagccgctctctcctgcctggctgacctcactgcaaccatcgtgcag
aacaaagcggtggccgagcagggtctggaggaaggagaggcggaggagaacaggggtaaa
gaggaggtggaggacatgggcctgggctggatggaggcctgctgtgcggcactggagctc
cacgctgctgagccagcggttcaggaagctgcgagctgggccattcacaatctgttactg
cacggcgctgcagtccaccaatcagaggacgagcaggatgagaggactccggttcacaga
cagttgatggcggccatgctgctccactcctcctctcccagcgtctttaaagctgctacc
agcgctattgccacactcattactcacaacggtaaaatgcgttctctgctgctgtccagc
ggcctccacgtcaacctggtagagatgatgaagagacattcagcctcagcagaagtttcc
atcagcgcctgcaaactgctcaaactgctgttccagggaaggtcagccagtctggatgac
ttaaacatggccatgagtcagatcctcagcaccatgaaggtccacaacttccagccggag
gttcagctggaggctcttcaggccagcctggtcttcctctgcccagacaggagcctaagg
gagcacggcacctcggtcgcagatcccgacatggccgacgtgtcgctgaaggtcctgaag
aaccagtgtgtggtggaaggagctcacaccctctacctggaggttctcaacaggttcatc
agcagcccgatcattcagaggtgtggcctgaaggtgctgtctgctctggctgactgctcc
ggtgcagtggacctgctctgccaacagggggccatagacacggtgctgcatacactacag
atgttcccacaggaacgagagatacactactggggcctgaccctgctcaactacctcgta
accaagaagaagctgtcgaggatgatcgtgcctgttctcgcctccgttgtggtcgtctcc
ctcatccagtacagagaagactcggagatgctcctgaagtgttttcaggtggccctgagg
atgcttgatgcgtgttcaggagcagctgctgaactgcagagagaagactttgacaggcag
atcttccaacacctcagggatgagactccagaccagagcaacagcccgctgcggaggtcg
gtatgcctcgctctgtctaagatgtggtgcgacccggagctacactacagcatgctggaa
aaggcctgcaaggacggagacacgacgatggccgagtgtctgatcgagctgggcgccgac
atcaacaggaagacgaagacggagtctctcatctaccaggtgtgtgaaaggggcgggcct
ctggagctggtggagctcctgctcagccgaggcgcgcacgagcagcatctgcgcagggct
ctggccgtgagcgtgaagcgcggcgacggacccacggtcattcagctcctgggccgtctg
ggtctggacctcaacaacagcgccctctgcttggggggcttcaggctggggcgcctggac
gctgcgtggctcagccccctgctggccgaaagaggaagagcgcacagtctacgttacaac
agcagtaaaggtatgagtttggccaggtacattcagtctctccagaagtccaagagcgtc
agcggtcctcccaggtcgatggccgacccctgtctgacctctggctacatttccgacgag
agcgacgactccagcttcagcttcgtctccatggacgacagcttgtttttcaacgacgac
atggagagcgacgggagtgattcactgccaggggttctttctcaaaaaccgcataataat
tcgacagaggagctgaggggggggtcctttaagagaaagcagggacgtcgcagacatgcc
agtgccgagagcggtcagaccgagagtgaacacagtgagtctgtacacaggagatatggg
aggactggctccacccacaaagtgttcggctctagtgaaagctccgcccctctgcccaaa
gagcgggagaggatccgcctgctggacctgtcggggaacgagttggactctctgtcctgt
ctgatggacgacagcttggtgcagcagcagctggggtatctcctccgcctcgacctgtgc
aacaacagtctgctggagtttccttcagctctttgccagagtctgtacagtctgactcga
ctggacctgcagggcaaccagctgcggtcgctgccggtggagctgctgtctctgccctcg
ctcagcacgctgaacgtctctcgtaactgcgtgggtcccctgctgaccttcgaccctgcc
gtcacctgcccctcgctgcggcagctcaacttgtctttcaacgaaatcactgcgtttcct
caggagctgggccgcgccatggatcagctggaggagctgtttatggaaggtaacagtata
actgagctgtgcacgcctctgtgtctgccggagatcaagctgctcgacgtgagcaagaac
ggcgtggagaacatttctccagactttctgaccagctgccccaaactggaaaccttcagc
gcctccatgaacaaaatctgttccctgtctcatctgccgtccaagatcacaacactgaaa
ctagcaaacaacagcttcacctatgtctctgaggccatacttgatcttacaaacttgagg
tcggtggacatgagaaccaacaacatcgctgttcttcctggcccgggattctgggcgtcc
agcaacctcagagagctgatgttcagtaagaactgcatcgcgtctctggacctgagcgga
ccagtctacaagtggacaagactagagaaactccacctgagtggcaacaagctcagtgag
attcctccgcagatcggcctgttggaaggcctgacctccctggacatgagccacaacgct
aacctgcgctccttccctgatgagatggggaaactaggccgactgtgggacctgccgctg
gatggtctgaagctccagctggatctcaagctcattggcagcaagaccaaagacatagtc
aggttcctgcagcagcggctgaagaaagcagtgccatactaccgcatgaagctcatcgtg
gtggggaatgccggcagcgggaagaccaccctgattcagcagctgatgaagctgaagcgc
tcccagttgaactcgaagacggccgccgtcggtatcgacgtcagggactggaccatcagg
gagcgggacaagaagaaaatggtgctgaacgtctgggacttctcaggtggagaggagttc
agcggctctcaccctcacttcctgacttccagagctctctacctggtggtttacaacctc
agcaaaggagccagtcaggtggacgcccttaaaccctggctcttcaacatcaaagcggtg
gctccgctctccccggtcatcctggtggggacacacacagatgtgagcgacgagctgcag
cttcaggcctgcctgaccaagatcaaagaggagctgctgaaccaccagggtttccccgcc
atcaccgactatcacatggtctccgtctgcgaggactcggacgccatggccagactccgc
aaggccatcgccagagaggtcgccagcttcaggatccagggccagcctgtgatgggccag
ctggttccggacagctacgtggagctggagcgccgggttgtcgtggagagggccagggtt
ccctcggagttccccgtcatcaggcaccgggagctgctgcagctcatccaggagagtcag
ctgcagctggaggaagctgagctgccgcacgccgtccacttcctcagtgaagccggggtt
ctgctgcactttgacgaccctgcacttcagctccaagagctctactttatcgacccacag
tggctgtgcaacatcatctcccagaaactgaaattaaagagctgtggcctgtgggaacat
cccaaaggagttgttcagcgctcggttgtggaaaagttcctttttgagaccaaatgtttc
ccgaagagccacctgacgcagttcttcaaactgctggagaagttccagatcgcgctgccg
ttcggagaggagcagctgctcgttcccagcaatttgtccaaacacaggccggtgatcgag
ctgcctcacagtgagaactcggaggtcatagtgcgtctttatgagatgccgtacttcccc
atggattattggtctcggcagatcagccgcctcctggaggtttcgtcgtacttgctctgt
ggaagagagaaagttgtgcgacccaaccggatctactggaggagaggcatttacctgagc
tggtcccctgaagcgtactgtctggtggaggcggcgtcggtggaggagaacccctccagc
ttcgtcaggataactgtcccgtcttcccgcagaggccgggtgttgatgggtcaggttgtg
gatcacgtggactccctgctggaggagtggtttcctggcctgctgaacaccgacatgcac
ggcagcggcgaggctctgctgaagaagtgggctctgtacagcttcgaggacggccaggag
tggagcaagatcctgctggaggacctcttcacctatttcgacaacgattttctgctggtg
aacccagaggaccctcggtgcacactgcccatctctcagatcgctcctgacttggtgctg
agtgatcagcctgcaggaacgatactggacagcgaggagctggatgtcgacatgtctaag
gaaaacagactgggggacggcggctttggaaccgtttatcgaggtgtctacaaaaacgaa
gaagtagccgtgaagatattcaataaacacgcatctgagctttacatctacagactcctc
agacaggagttggcggtgttgggtcgcctccgtcaccccagcctggtcggcctgctggcg
gccggctcaactcctcaggtcctggtgatggagctggctctgcgcggctcgttggactcc
ctgtttgaacacgagaacggcagcctcaactggaagctccagcacaggatcgccctgcag
gtggctgacggactcaggtaccttcactcggccatgatcatctatcgggatctgaagcca
cacaacgtgcttctgttcaacctgaagaccaactccgagatcatcgccaagatcacagac
tacggcatcgctcagtactgctgcagcatgggagtgagaagctcagagggcactccaggt
ttccgagcaccagaggtcgcccggggtaacgtgatctacaaccagcaggctgatgtgttc
tcattcggcctcctgctctacgacctcctgacctgcggtgagcgcatctctgacggcatg
aagttccccagtgagtttgatgaagtcgcagtgcaggggaagctgccagatccagtagaa
cactacggctgctcgccttggcccggcttccagacgctgatgaaggactgtctgagggaa
agtccgcaggaccgaccgacgtctgctcaggtgtttgatcggctgaattcgggggagatg
ctgtgtctgatgaaggagctggtggttccccgggcgttcaacgccgagtgcctcacaatg
agctctgccagcagtgacagtccgttcagcagccacagagcctggctgggagggggcagc
agcaccagcagccacagggtgggctccatcacagccgtggacctggacaccaacgcagtc
atgacacaggacatcgacaccagtcccgtcctgtgtctggtgacggttcaaatccccaac
gaggcctgtgattggctggtggctggcacacagtctggctccttagtggtcatcagcacc
caggacatgtcgacttggcaccacctgcagagcgtcacggatgctgtcacctcactgtac
ttccacgtgcaccctcgtcgaacccaaagaaagaattatttgctggttggaacagccaat
ggacttctcactgtttatgaggactctgttctcaagcaggaaaaaggtcagccggttaaa
actgtcacagtgggaaacgtcagcacgcccgtcatgtgtctgggccagtcgctgcactcg
ctggacggcaggtccgtgtgggccggctgcgggaccaggatcctctccttcaccgccgag
tacgacgtctgcaggaccatcgacaccagaccgaacctcttcttccagcagcagcgatca
ctggctggtgagtcgtgtgtgttgcgaatggttgtggataaatacgtgtacctgaacaaa
gctgggacgccgacggtcgaggtttgggacaagaggagtgagaggatggtggactgcatc
gactgcgctcatatcatcagacatggctccggctgcagaggccggcagggcagcgaggcg
gagctgcccaccgaagcggccccctcctgggccagagtgaaggccctgctggttcagacc
gctgcagctctctgggtcggcaccagagggggccacctgctgctgctggagctctccaaa
caccagacgctgcaggtcatcggcccccgctgcgactccatccgctgcatcgcctctgca
ctcatagaaacactaaactggaagaatgtggtgctgactttgggcagaagactcccacaa
gacaagaatcagtttgacgaggagtcggtgctgatggcgtggaacagcacgctgccgatg
gaggtcaaagacctgaacagacactgcgagaagagagagcagatcgcagccaaaatgaga
gagcagcttcatcacagctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (37)   
   Pfam (37)   
All databases (52)   

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