KEGG   Salmonella enterica subsp. enterica serovar Choleraesuis: SCH_030
Entry
SCH_030           CDS       T00240                                 
Symbol
tri
Name
(GenBank) dihydrofolate reductase
  KO
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
sec  Salmonella enterica subsp. enterica serovar Choleraesuis
Pathway
sec00670  One carbon pool by folate
sec00790  Folate biosynthesis
sec01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:sec00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SCH_030 (tri)
   00670 One carbon pool by folate
    SCH_030 (tri)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:sec01504]
    SCH_030 (tri)
Enzymes [BR:sec01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SCH_030 (tri)
Antimicrobial resistance genes [BR:sec01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    SCH_030 (tri)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAS76314
UniProt: H9L4V5
Position
pSC138:24578..25075
AA seq 165 aa
MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGKVVVMGRKTFESIGKPL
PNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVAGGAEIYTLALPHAHGVFL
SEVHQTFEGDAFFPMLNETEFELVSTETIQAVIPYTHSVYARRNG
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaactcggaatcagtacgcatttatctcgttgctgcgatgggagccaatcgggttatt
ggcaatggtcctaatatcccctggaaaattccgggtgagcagaagatttttcgcagactc
actgagggaaaagtcgttgtcatggggcgaaagacctttgagtctatcggcaagcctcta
ccgaaccgtcacacattggtaatctcacgccaagctaactaccgcgccactggctgcgta
gttgtttcaacgctgtcgcacgctatcgctttggcatccgaactcggcaatgaactctac
gtcgcgggcggagctgagatatacactctggcactacctcacgcccacggcgtgtttcta
tctgaggtacatcaaaccttcgagggtgacgccttcttcccaatgctcaacgaaacagaa
ttcgagcttgtctcaaccgaaaccattcaagctgtaattccgtacacccactccgtttat
gcgcgtcgaaacggctaa

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