KEGG   Salmonella enterica subsp. enterica serovar Typhimurium T000240: STMDT12_C42490
Entry
STMDT12_C42490    CDS       T01742                                 
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
sem  Salmonella enterica subsp. enterica serovar Typhimurium T000240
Pathway
sem00260  Glycine, serine and threonine metabolism
sem00261  Monobactam biosynthesis
sem00270  Cysteine and methionine metabolism
sem00300  Lysine biosynthesis
sem01100  Metabolic pathways
sem01110  Biosynthesis of secondary metabolites
sem01120  Microbial metabolism in diverse environments
sem01230  Biosynthesis of amino acids
Module
sem_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sem_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
sem_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:sem00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    STMDT12_C42490 (metL)
   00270 Cysteine and methionine metabolism
    STMDT12_C42490 (metL)
   00300 Lysine biosynthesis
    STMDT12_C42490 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    STMDT12_C42490 (metL)
Enzymes [BR:sem01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     STMDT12_C42490 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     STMDT12_C42490 (metL)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3 HTH_11
Other DBs
NCBI-ProteinID: BAJ39192
NITE: STMDT12_C42490
Position
4415965..4418397
AA seq 810 aa
MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVLQTLRRYQCDLISGLLPADAADDLTSAFISDLERLAALLDGGVTDA
VYAEIVGHGEIWSARLMSAVLNQQGLDAAWLDARAFLRAERAAQPQVDEGLSYPLLQQLL
AQHPGKRLVVTGFISRNHDGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDICLIEFQVPASQDFRLAHKELDHILKRAQVRPLAVGVHRDRQLL
QFCYTAEVADSVLKLLDDVGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLMLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLNYEGLDASRALAFFDDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASAQLADQYLDFASHGFHVISANKLAGASASDKYRQIHDAFEKTGRYWLYN
ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDALNE
QMVQRLEAARELGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq 2433 nt   +upstreamnt  +downstreamnt
atgagtgtgattgcgcaggcaggggcgaaaggtcgtcaactgcataaatttggcggcagt
agtctggcggatgtgaagtgttacctgcgtgtcgcaggcattatggcggagtattcgcag
cctgacgatatgatggtagtgtccgccgcaggcagtaccaccaaccagttgattagctgg
ctcaagttaagccagaccgatcgcctttctgcgcatcaggtattacagacgttacgccgc
taccagtgcgatctgattagcgggctgcttcccgccgacgcggcagatgatttaaccagc
gcttttattagcgatctggaacgtcttgccgccttgctcgacggcggcgtaacggatgcc
gtctatgctgagatcgtcggacacggcgaaatttggtcggcgagattgatgtccgccgtc
ctgaatcagcaggggctggatgccgcctggctggacgcgcgcgcatttttacgcgccgaa
cgcgccgcacagccgcaggttgatgaagggctatcttatcctttattgcagcagctactg
gcgcagcatccgggcaaacgtctggtcgtgaccggctttatcagccgcaatcatgacggc
gaaacagtcctgttaggccggaacggttccgactattccgccacgcaaatcggcgcgctg
gcgggcgtttcccgcgtgaccatctggagcgatgtcgcgggcgtttatagcgccgacccg
cgcaaagtgaaagatgcctgcctgctgccgttgctgcgtctggacgaagccagcgagctg
gcgcgtctggcggcgcctgttctgcacgcccgcacgctacagccagtgtccggcagcgat
atcgatttgcagttgcgctgtagctacacgccggatcaagggtcaacccgaattgaacga
gtgctggcttccgggacgggcgcgcgtatcgtgaccagtcacgatgatatctgtctgatt
gagtttcaggtgccagccagccaggatttcaggctggcgcataaagagctcgaccacatt
ttaaaacgggcgcaggtgcgtccgctggcggtgggcgtgcatcgcgatcgccagctattg
cagttctgctataccgccgaggtagcggatagcgtactgaaactcctcgacgatgtcggg
ctgccgggcgaattgcgcctgcgacaggggctggcgctggtggcgatggtcggtgcgggc
gtcactcgcaatccgctacactgccatcgcttctggcagcagttgaaaggtcagccagtg
gagtttacctggcagtcggaggagggcatcagtctggtggcggtgctgcgtaccggccca
actgagagcctgattcaggggctgcatcagtctgttttccgcgccgaaaaacgcattggc
ctgatgctgttcggtaaggggaacatcggctcccgttggctggaactgtttgcccgtgaa
caaagcacgctttccgcgcgtactggttttgaatttgtgctggcgggcgtggtggatagc
cgccgtagcctgttgaattatgaagggctggacgccagccgcgcgttggcattctttgat
gatgaagccgttgagcaggacgaagagtcgctattcctgtggatgcgtgcgcatccgtat
gatgatttagtggtgctggatgtaaccgccagtgcacagttagccgatcagtaccttgat
ttcgccagccacggttttcatgtgattagcgccaataaactggcgggcgcaagcgccagc
gataagtatcgccagattcatgacgcgtttgaaaaaaccgggcgttactggctgtataac
gccaccgtgggcgcgggattgccgatcaaccacacggtgcgggatctgattgacagcggc
gatacgattctctcgatcagcgggatcttctccgggacgctatcctggctgttcctgcaa
tttgacggtacggtgccgttcaccgatctggtggatcaggcctggcagcaggggctgacc
gaacccgatccgcgcgtcgatctttccggaaaagatgtcatgcgtaagctggtgattctg
gcgcgcgaggcgggatacgacatcgagccggatcaggtgcgtgtagaatcgttggtgccg
gcgcattgtgaagaaggatctatcgatcactttttcgaaaacggcgacgcgctgaatgaa
cagatggtgcagcgtctggaggcagcccgcgaactggggctggtgttgcgttacgtggcg
cgtttcgacgccaatggcaaagcgcgcgtcggcgttgaagcggtgcgtccggaacatccg
ctggcggcgctgctgccgtgcgataatgtctttgctattgaaagccgctggtatcgcgat
aacccgctggtgatccgtgggccgggcgcgggtcgcgatgtgaccgccggggcgattcag
tcggatatcaaccgtctggcgcagttgctgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NITE (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (40)   

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