KEGG   Streptomyces pratensis: Sfla_3239
Entry
Sfla_3239         CDS       T01647                                 
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
sfa  Streptomyces pratensis
Pathway
sfa00280  Valine, leucine and isoleucine degradation
sfa00640  Propanoate metabolism
sfa00785  Lipoic acid metabolism
sfa01100  Metabolic pathways
sfa01110  Biosynthesis of secondary metabolites
sfa01210  2-Oxocarboxylic acid metabolism
Module
sfa_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:sfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Sfla_3239
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Sfla_3239
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Sfla_3239
Enzymes [BR:sfa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     Sfla_3239
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N AAA_25
Other DBs
NCBI-ProteinID: ADW04660
UniProt: A0A8D3WGU1
Position
3750410..3751570
AA seq 386 aa
MTVESTAARKPRRSSKRTSAAKTPAKTQEGSGPQLVQLLTPEGERVEHPDFEIDLSAEEL
RGLYRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHG
VAWCRGVDPTNLLGMFRGVNHGGWDPNTNNFHLYTIVIGSQTLHATGYAMGVAKDGADSA
VIAYFGDGASSQGDVAEAFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQRAQGFG
FPGVRVDGNDVLACLAVTRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADEERA
AWEAKDPILRLRTYLEKQELADAAFFTALEEESETLGKRVREAVRAMPDPDRLAIFDHAY
ADGNPLVDEERAQFAAYQASFAEEGN
NT seq 1161 nt   +upstreamnt  +downstreamnt
gtgaccgtggagagcactgccgcgcgcaaaccgcgacgcagcagtaagcggaccagcgcc
gcgaagacgcccgcgaagacgcaggagggctccggcccccagctggtacagctgctgacg
cccgagggcgagcgcgtcgagcacccggacttcgagatcgacctcagcgcggaggagctc
cgcgggctctaccgggacatggtcctgacccgccggttcgacgccgaggccaccgcgctg
cagcgccagggcgagctgggcctgtgggcctcgctgctgggccaggaggccgcgcagatc
ggctccggccgcgcactgcgcgacgacgactacgtcttcccgacctaccgggagcacggt
gtcgcctggtgccggggcgtcgacccgaccaatctgctcggcatgttccgcggcgtgaac
cacggcggctgggacccgaacaccaacaacttccacctctacacgatcgtcatcggctcg
cagaccctgcacgccaccggctacgccatgggcgtcgccaaggacggtgcggactcggcc
gtgatcgcgtacttcggtgacggtgcctccagccagggcgacgtcgccgaggcgttcacc
ttctccgccgtctacaacgcccccgtcgtgttcttctgccagaacaaccagtgggcgatc
tccgagccgaccgagaagcagacgcgggtgccgctctaccagcgcgcgcagggcttcgga
ttccccggcgtccgggtcgacggcaacgacgtcctcgcgtgcctggccgtgaccaggtcg
gcgctggagcgtgcccggcggggcgagggacccaccctcgtcgaggcgttcacctaccgc
atgggcgcccacaccacctccgacgacccgaccaagtaccgggcggacgaggagcgggcg
gcctgggaggcgaaggacccgatcctgcggctgcgtacgtacctggagaagcaggagctc
gccgacgcggcgttcttcaccgcgctggaggaggagagcgagaccctcggcaagcgggtg
cgcgaagcggtgcgggcgatgcccgacccggaccggctggcgatcttcgaccacgcctac
gccgacgggaatccgctcgtcgacgaggagcgcgcccagttcgccgcctaccaggcatcg
ttcgccgaggagggcaactag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (55)   

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