KEGG   Streptomyces pratensis: Sfla_4643
Entry
Sfla_4643         CDS       T01647                                 
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
sfa  Streptomyces pratensis
Pathway
sfa00010  Glycolysis / Gluconeogenesis
sfa00020  Citrate cycle (TCA cycle)
sfa00620  Pyruvate metabolism
sfa00785  Lipoic acid metabolism
sfa01100  Metabolic pathways
sfa01110  Biosynthesis of secondary metabolites
sfa01120  Microbial metabolism in diverse environments
sfa01200  Carbon metabolism
sfa01210  2-Oxocarboxylic acid metabolism
Module
sfa_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:sfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    Sfla_4643
   00020 Citrate cycle (TCA cycle)
    Sfla_4643
   00620 Pyruvate metabolism
    Sfla_4643
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Sfla_4643
Enzymes [BR:sfa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     Sfla_4643
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C DUF3135 Transket_pyr
Other DBs
NCBI-ProteinID: ADW06044
UniProt: A0A8D4BCH5
Position
complement(5352962..5355631)
AA seq 889 aa
MTDPVAKLPSELDQLPDRDPEETAEWAASLDAVTKAAGPHRAAYLMRRSLQHAEGAGIAL
PKLLETDYVNTIPTSAEPAFDGDLEMESKITAWNRWNAAAMVTRGARYGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLSEQQLDNFRQESGGDG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRKIKDTSNSHVWAFLGDGEM
DEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFRVVQELEGAFRGAGWNVVKTL
WGNAWDELFQLDTTGALIRRLREVPDAQFQTYATRDVAYIREHFFGTDPALVELAKLLSD
AKIGECFYSSRGGHEARKVYAAYRAALEHKGAPTVILAQTVKGYTLGKGFESKNANHQMK
KLSIDEFKGMRELLGLPIPDSAFEDGLVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
AVALPEPEERAFKALYKGSGKQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAAASSYATH
GETMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVKDGLRRMYGPEAEDVFYYLTVYNEPKQQPAMPEGVEEG
IVKGLYRFKEGTPSTADAPRIQLLGSGTAIHWVLEAQELLAADWGVTADVWSATSWGELR
RDALESDEALLRGEERVPYVTQALSGAAGPVLAVSDWMRAVPDQISQWVEQDWSSLGTDG
FGLSDTREGARRHFGVDPQSVVVAALAQLARRGEIPVSKVKEAREKYGM
NT seq 2670 nt   +upstreamnt  +downstreamnt
atgaccgaccccgtagcaaagcttccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgagtgggcggcctccctggacgccgtcaccaaggccgcgggcccgcac
cgcgccgcctacctgatgcgacgttcgctgcagcacgccgagggcgccggcatcgcgctg
cccaagctgctggagaccgactacgtcaacaccatccccacctccgccgagcccgcgttc
gacggcgacctggagatggaatcgaagatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccgcggcgcccggtacggcgtcggcggccacatcgccacgttcgcctcggcg
gcctggctgtacgagaccggcttcaaccacttcttccgcggcaaggaaggtgacggctcc
ggcgaccagctctacatccagggccacgcctcgcccggcatctacgcccgcgccttcctc
gacggccgcctctccgagcagcagctcgacaacttccgccaggagtcgggtggcgacggc
ctgccctcctacccgcacccgcggcggctgccctggctgtgggagttccccacggtgtcg
atgggcctcggccccctctcggcgatctaccaggcgcgcttcaaccgctacctgaccaac
cgcaagatcaaggacacgtcgaactcgcacgtctgggccttcctgggcgacggcgagatg
gacgagcccgagtcgaccgctgccctcgccctcgcggcccgtgagcagctcgacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttccgc
gtggtccaggagctggagggcgcgttccgcggagccggctggaacgtcgtgaagacgctc
tggggcaacgcctgggacgagctgttccagctggacaccacgggcgcgctgatccgccgt
ctccgcgaggtcccggacgcgcagttccagacgtacgcgacgcgtgacgtggcctacatc
cgcgagcacttcttcggcaccgacccggcgctcgtcgagctggcgaaactcctgagcgac
gcgaagatcggcgagtgtttctacagctcccgcggtggtcacgaggcccgcaaggtgtat
gcggcctaccgtgccgcgctggagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggctacacgctgggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctgtcgatcgacgagttcaagggcatgcgcgagctgctcggcctcccgatcccggac
agcgccttcgaggacgggctggtcccctacggccacccgggcgccgactcccccgaggtg
cgctacctccaggagcgccgtgcggctctcggcggcccggcccccgcccgccgggtgcac
gccgtggcgctgcccgagccggaggagcgtgccttcaaggccctgtacaaggggtccggc
aagcaggagatggccaccaccatggcgttcgtccgcctggtgaaggacctgatgcgggac
aaggagaccggcaggcgctgggttccgatcgtcccggacgaggcccgtaccttcggtatg
gagtcgctgttcccctcggcgggcatctactccccgctcggccagacgtacgagccggtc
gaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgagggg
atcaccgaggccggtgccatggccgacttcatcgccgccgcctcgtcgtacgcgacgcac
ggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcggaccggc
gaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccacggcc
ggccgtacgaccctgacgggtgagggcctccagcacgccgacggccactcgcacctgatc
gcgtccacgaaccccgcgtcgctcaactacgacccggcgttcgcgtacgagatcgcggtg
atcgtcaaggacggtctgcgcaggatgtacggccccgaggccgaggacgtcttctactac
ctgacggtctacaacgagcccaagcagcagcccgcgatgccggaaggcgtcgaggagggc
atcgtcaagggcctctaccgcttcaaggagggcacgccctccaccgcggacgcgccccgg
atccagctgctgggctccggtacggcgatccactgggtcctggaggcccaggaactgctc
gccgccgactggggcgtcacggcggacgtgtggtccgccacctcgtggggtgagctgcgc
cgcgacgcgctggagtccgacgaggcgctgctccgcggcgaggagcgggtgccgtacgtg
acccaggcgctgtcgggtgcggcaggcccggtcctggccgtcagcgactggatgcgcgcg
gtcccggaccagatcagccagtgggtggagcaggactggtcctcgctcggcacggacggc
ttcggtctctccgacacccgcgagggcgcccgccgccacttcggtgtcgacccgcagtcc
gtcgtggtcgccgcgctggcccagctggcccgccgtggcgagatcccggtctcgaaggtc
aaggaggcccgggagaagtacgggatgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (38)   

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