KEGG   Shigella flexneri 2002017 (serotype Fxv): SFxv_4445
Entry
SFxv_4445         CDS       T01883                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
sfe  Shigella flexneri 2002017 (serotype Fxv)
Pathway
sfe00230  Purine metabolism
sfe00670  One carbon pool by folate
sfe01100  Metabolic pathways
sfe01110  Biosynthesis of secondary metabolites
Module
sfe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:sfe00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SFxv_4445 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SFxv_4445 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sfe04147]
    SFxv_4445 (purH)
Enzymes [BR:sfe01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     SFxv_4445 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     SFxv_4445 (purH)
Exosome [BR:sfe04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   SFxv_4445 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS NSP2_assoc
Other DBs
NCBI-ProteinID: ADA76374
UniProt: D2AD83
Position
complement(4264561..4266150)
AA seq 529 aa
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFC
WKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFP
FRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
NT seq 1590 nt   +upstreamnt  +downstreamnt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaagccggtatc
gtcgaattcgcccaggcactttccgcacgcggtgtggagctgctgtctacagggggcact
gcccgtctgttagcagaaaaaggtctgccggtaaccgaagtttccgattacaccggtttc
ccggagatgatggatggacgcgtgaagaccctgcatccgaaagtacatggtggcattctg
ggccgtcgcggccaggacgatgccattatggaagaacatcagatccagcctatcgatatg
gtggttgttaacctgtatccgttcgcccagactgttgctcgtgaaggctgctcgctggaa
gatgcggttgagaacatcgatatcggcggcccgaccatggtgcgctccgccgctaagaac
cataaagatgtcgcaatcgtggtgaagagcagcgactacgacgccattattaaagagatg
gatgacaacgaaggatcgctgacgcttgcaacccgtttcgacctcgccatcaaagccttc
gaacacactgccgcctacgacagcatgattgccaactacttcggcagcatggttccggcg
taccacggtgaaagcaaagaagccgccggtcgcttcccacgcacgctgaacctgaacttc
attaagaagcaggatatgcgttacggcgagaacagccaccagcaggctgccttctatata
gaagagaatgtgaaagaagcctccgttgctaccgcaacccaggttcagggtaaagccctc
tcttataacaacatcgccgataccgatgcggcgctggagtgcgtgaaagagttcgccgag
ccggcatgtgtgattgtgaagcacgccaacccttgcggtgtagctatcggcaattccatt
cttgatgcttacgatcgcgcgtacaaaaccgacccaacctccgcattcggcggcatcatt
gcctttaaccgcgagctggatgcggaaaccgcacaggccatcatttctcgtcagtttgtc
gaagtgattattgcgccttccgccagcgaagaagccctgaaaatcaccgccgccaagcag
aacgtacgcgttctgacctgcggtcagtggggcgagcgtgttccgggtcttgatttcaaa
cgcgtgaacggcggtctgctggttcaggatcgtgacctggggatggtcggtgcggaagaa
ctgcgcgtcgtcacccaacgtcagccgaccgaacaggaactgcgtgatgcgctgttctgc
tggaaagtggcgaaattcgtgaaatccaatgctatcgtctatgccaaaaacaatatgacc
atcggtattggcgcgggccagatgagccgcgtgtactccgcgaaaatcgccggtattaaa
gctgccgatgaaggcctggaagtgaaaggttcctcgatggcttctgacgcgttcttcccg
ttccgcgacggtattgatgccgccgccgctgcgggcgtgacctgcgtaatccagcctggc
ggttccatccgtgatgacgaagtgattgccgccgccgacgagcacggtattgcgatgctc
ttcaccgacatgcgccacttccgccattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (26)   

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