KEGG   Sphingorhabdus sp. SMR4y: SPHFLASMR4Y_00946
Entry
SPHFLASMR4Y_00946 CDS       T04949                                 
Symbol
mrdA
Name
(GenBank) penicillin-binding protein 2
  KO
K05515  penicillin-binding protein 2 [EC:3.4.16.4]
Organism
sfla  Sphingorhabdus sp. SMR4y
Pathway
sfla00550  Peptidoglycan biosynthesis
sfla01100  Metabolic pathways
sfla01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:sfla00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SPHFLASMR4Y_00946 (mrdA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    SPHFLASMR4Y_00946 (mrdA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sfla01011]
    SPHFLASMR4Y_00946 (mrdA)
Enzymes [BR:sfla01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     SPHFLASMR4Y_00946 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:sfla01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   SPHFLASMR4Y_00946 (mrdA)
SSDB
Motif
Pfam: Transpeptidase PBP_dimer
Other DBs
NCBI-ProteinID: ASK87722
UniProt: A0A220W4H1
Position
986018..987985
AA seq 655 aa
MKPAKTISSAMQELTFTRRATVIGGLQIGVGVLLAARMAYISVAENEHYKLLSESNRVNL
TLVPPRRGWLIDRSGKPIANNKTDFRIDIIPDRLRDKEKTVATLANLLSLDPEELERINR
ELEQAGSFQPVQVATGLDSEQYAAVSVRLPDLPGVSPRQGFSRNYPSGPAIGHLVGYVGI
ASAEDYKENPDPILITPGYKIGKDGLEKMFEDHLQGEPGAKRVEVTARGKIVRELNTRPD
VPGKPLQLTLDIDLQEYAARRLGPESGSVVVIDCLTGDILTMTSMPSFDPNSFSDGIGVT
EYGMLREDDHVPLLDKSLKSLFPPGSTVKPMVGLSFLEAGLDPDETVNCNGGLQVGNRRF
RCWKRGGHGRVDLAKGIYQSCDVYFYYFAQKIGINPIALMANRLGLGQKYPLPVASQFYG
TVPDPAWLRKKHKREWQAYDTVNTTIGQGYMLVNPTQLAVMASRLATGKNIVPRLIMDEK
KSPIQTLNLDPEHLLYVQKAMSDVVNGPGTAGRARLPLDDVKMAGKTGTAQVVNLDFGRG
GQDVAWKYRDHGLFVCFAPYDNPRYAAAVVIEHGGGSGAAYPVARDVLTFLYDRQKAMDV
LAGLEKSWGGTIQERMDRKMAAYRARKNLEKAMAENPAAAEADTADSSADATAGE
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgaaaccggcgaaaacgatcagcagcgccatgcaggaactgaccttcacccgcagggca
acggtaattggcggtctgcagatcggcgttggcgtgctgctggcagcgcgtatggcctat
atttcggtagccgagaacgaacattacaagctgttgtcggaaagcaaccgggtcaatctc
acgctcgtgccaccgcgccgtggctggctgatcgaccggagtggcaagccgattgccaac
aacaagaccgattttcgtatcgacatcattcccgaccggctgcgcgacaaggaaaagacc
gtagcgactctggcgaatctgctgtccctcgacccggaggagcttgagcggatcaatcgg
gagctggaacaggccggcagtttccagcccgttcaggtcgcgaccggactggattccgaa
caatatgccgccgtcagtgtccgccttcccgatttgcccggcgtgtcgcctcgacagggc
ttttcccgcaattatccgagcggtccggcgatcggccatctggtcggctatgtcggcatt
gcctcggcagaagattataaggaaaacccggatccgatattgattactccggggtacaag
atcggcaaggacggcctcgaaaagatgttcgaggaccatttgcagggcgagcccggcgca
aagcgggtcgaagtaacggctcggggcaagatcgtccgcgagctcaacacccggcccgac
gttcccggcaagccgctgcaactgactctcgatatcgacctgcaggaatatgcagcccgg
cgtctcggccccgaatccgggtctgtggtggtcatcgattgcctgaccggtgatatcctg
acgatgacctcgatgccgtcttttgacccgaacagcttctccgacggcattggcgtcacc
gaatatggcatgttgcgcgaagatgatcatgtgccgctgctcgacaagtctctgaaaagc
ctgttcccgccggggtccacggtcaagccgatggttggcctgtcctttctggaagcgggg
ctcgatcccgatgaaacggtcaattgcaatggcggactgcaggtcggcaaccggcgcttc
cgctgctggaaacgcggcggtcacggacgggttgacctggccaagggcatttaccagagc
tgcgatgtctatttctattattttgcccagaaaatcggcatcaatccgatcgcgctgatg
gccaaccgtctgggtcttggtcagaaatatccgctgccggtggccagccagttttacggc
acggtccccgatccggcctggctgcgcaaaaagcacaagcgcgaatggcaggcctatgac
acggtcaataccaccatcggccagggctatatgctggttaatccgacccagctcgcggtc
atggcgtcacggctcgcgaccggcaagaatatcgtccctcgcctgatcatggatgaaaaa
aaatcacccatccagacgctcaatctcgaccccgagcatctgctctacgtccagaaggcg
atgagcgatgtggtcaacgggccgggtactgccggacgggcgcgcctgccgcttgacgat
gtcaagatggcaggcaagaccggtaccgcgcaggtggtcaatctcgacttcgggcgcggc
ggtcaggatgtcgcctggaaatatcgcgaccacggcctgttcgtgtgcttcgctccttat
gataatccgcgctatgcggccgctgtggttatcgaacatggcggcgggtccggcgcagcc
tatccagttgccagggacgtactgacctttctctatgatcgccagaaagcaatggatgtg
cttgccgggctggaaaaatcctggggcggcacgatccaggaacggatggaccgcaagatg
gccgcctatcgcgcccgcaagaatctcgaaaaggcaatggccgaaaacccggccgctgcc
gaagcggacacggccgacagcagcgctgatgccaccgcgggagaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (14)   

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