KEGG   Streptomyces griseoviridis: ELQ87_03590
Entry
ELQ87_03590       CDS       T06660                                 
Name
(GenBank) FAD-dependent oxidoreductase
  KO
K14257  tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
Organism
sgd  Streptomyces griseoviridis
Pathway
sgd00253  Tetracycline biosynthesis
sgd00404  Staurosporine biosynthesis
sgd01057  Biosynthesis of type II polyketide products
sgd01100  Metabolic pathways
sgd01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:sgd00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    ELQ87_03590
   00253 Tetracycline biosynthesis
    ELQ87_03590
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    ELQ87_03590
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:sgd01008]
    ELQ87_03590
Enzymes [BR:sgd01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.49  tetracycline 7-halogenase
     ELQ87_03590
Polyketide biosynthesis proteins [BR:sgd01008]
 Polyketide tailoring proteins
  Halogenase
   ELQ87_03590
SSDB
Motif
Pfam: Trp_halogenase FAD_binding_3 DAO Lycopene_cycl Pyr_redox_2 NAD_binding_8 FAD_oxidored HI0933_like GDI FAD_binding_2 ApbA 3HCDH_N UDPG_MGDP_dh_N
Other DBs
NCBI-ProteinID: AZS83471
UniProt: A0A3Q9KSM3
Position
complement(840556..842199)
AA seq 547 aa
MKHTDRYDVAILGSGMAGGMLGAVLARNGVKVLLLDAGTHPRFAVGESTIPYTSGMTRLI
ADRYRVPELRALSSFKGIREHVSRNCGQKQNFGFVYHREGVPQDPREINQLVVPSVLRTE
THLFRQDIDAYLFHVAVKYGAQPRLNTRIVDIETDPGTGAVLRTDGGEEFRAQYVVDGSG
FRSPLAEKFALRETPTRARTHSRCLFTHMTGVEPFDKAPAARRHDQPNPWHHGTLHHVFE
GGWLWVIPFDNHADSLNPLCSVGLTLDPRKHPKDDRTPQAEFDAFLARFPEIAHQFREAR
AVRPWVSTGRLQYSAKQVVGERFCLTSHAAGFIDALYSRGLTNTMELVNALGWRLIAASR
DGDWSMARFGYLEDLQQGLFDFHDDIVHSSFVGFRDYELWNAVNRTWMLGTMLGNVMLED
AYYRFERTGDDRVFRELEEHGSPGSPLPVSAGFTRMGPLTRELCQAVEEGTESPGEAARA
ILSYIRDADFIAPSFRFGERDTRCFAMSPAKMAMNARWCRRDAPPEIGPRMINASKGLVR
MRLRAGR
NT seq 1644 nt   +upstreamnt  +downstreamnt
atgaagcacactgaccgatacgacgtggcgatcctcggcagcggcatggccggcgggatg
ctgggcgcggtcctggcccgcaacggcgtgaaggtgctgctcctcgacgccggcacgcac
ccccggttcgcggtgggggagtccaccatcccctacacctccgggatgacgcggctgatc
gccgaccgctaccgagtccccgaactgcgggccctgtccagcttcaagggcatccgcgaa
cacgtctcgcgcaactgcggacagaagcagaacttcgggttcgtctaccaccgcgagggc
gtcccccaggacccgcgggagatcaaccagctggtcgtgccgtccgtcctgcgcaccgag
acccatctgttccgccaggacatcgacgcctacctcttccacgtggccgtgaagtacggc
gcccagccgcggctgaacaccaggatcgtggacatcgagaccgaccccggcaccggcgcc
gtcctgcgcaccgacggcggcgaggagttccgcgcccagtacgtcgtcgacggcagcggg
ttccgctcaccgctcgccgagaagttcgcgctgcgggagacacccacccgcgccaggacg
cactcccgctgcctgttcacccacatgaccggcgtcgagcccttcgacaaggcccccgcc
gcccgccgccacgaccagcccaacccctggcaccacggcaccctgcaccacgtcttcgaa
ggcggctggctctgggtcatcccgttcgacaaccacgccgactcgctcaacccgctgtgc
agcgtcggcctcaccctcgacccccgcaagcaccccaaggacgaccgcaccccacaggcg
gagttcgacgcgttcctggcccggttccccgagatcgcgcaccagttccgcgaggcgcgg
gcggtccgcccctgggtctccaccgggcggctccagtactcggcgaaacaggtggtcggc
gagcggttctgcctcacctcgcacgccgcgggcttcatcgacgccctgtactcgcgcggc
ctcaccaacaccatggaactcgtcaacgccctcggctggcgcctcatcgccgccagccgc
gacggcgactggtccatggccaggttcggctacctggaggacctccagcagggcctgttc
gacttccacgacgacatcgtgcacagctccttcgtgggcttccgcgactacgagctgtgg
aacgccgtcaaccgcacctggatgctcggcaccatgctcggcaacgtcatgctggaggac
gcctactaccggttcgaacgcaccggcgacgaccgcgtcttccgggagctggaggaacac
ggcagccccggctccccgctccccgtcagcgccggcttcacccggatgggcccgctcacc
agggaactgtgccaagccgtcgaggagggcaccgagagcccgggggaggcggcccgcgcg
atcctctcgtacatccgggacgccgacttcatcgcaccgtccttccggttcggcgagcgg
gacacccgctgcttcgcgatgtccccggcgaagatggccatgaacgcccgctggtgccgc
agggacgcgccgcctgagatcggcccccgcatgatcaacgccagcaagggcctggtccgg
atgcggctgcgggcgggcaggtag

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