KEGG   Streptomyces griseochromogenes: AVL59_19215
Entry
AVL59_19215       CDS       T04729                                 
Name
(GenBank) hypothetical protein
  KO
K14257  tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
Organism
sgs  Streptomyces griseochromogenes
Pathway
sgs00253  Tetracycline biosynthesis
sgs01057  Biosynthesis of type II polyketide products
sgs01100  Metabolic pathways
sgs01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:sgs00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    AVL59_19215
   00253 Tetracycline biosynthesis
    AVL59_19215
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    AVL59_19215
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:sgs01008]
    AVL59_19215
Enzymes [BR:sgs01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.49  tetracycline 7-halogenase
     AVL59_19215
Polyketide biosynthesis proteins [BR:sgs01008]
 Polyketide tailoring proteins
  Halogenase
   AVL59_19215
SSDB
Motif
Pfam: Trp_halogenase Luciferase FAD_binding_3
Other DBs
NCBI-ProteinID: ANP51454
UniProt: A0A1B1AY05
Position
4524807..4526612
AA seq 601 aa
MLACILARHGVSTLLLEGASHPRFTIGESLIPETGLRLRIVADKYGVPEIGWIGTFHKLR
KHVSSNCGVKRSFGFMYHRAGEENRPEEINQFGTLTPPAGPDSHLFRQDTDAFLAALSVK
YGATFRSQTRISDITFGDDEVELRAASGETYRAKLLIDASGMRSMVSDQLGMRDEVPRFR
TDTRTIYTHMMGVRSADLLLDPKGRRNLISPLGQSTMHHVFDGGWMWVIPFSNHRDATNP
LTSVGLMLDRRKHPDPQGTPEQEFRRVISAYPTVARHFAEANAARPWVRSGRIQYSSPHL
IAPRLIQLPHAAAFIDPLYSSGMSVLVVAVDLIAESLLKAVAENDYATERFKFMEDVVNR
GFDHYDTIVSGSFDSFASYDTWNAWNRNWVMGSLLGTFGPLSLLMHYHKTKDRSYLEKTT
EPSRMGVLGSHLPGVVDMARASRADMDAAIAGRITHKEASERIFARFRATDFLPPYMGFG
DPRKTATATFTLIPGARHVTWYRMHGDPVYRDNCTFPLMTYARDGATFVLGEARDAWRRS
FSALRDVFFAHNSDWRHIAPALAEHGELVTPVPASAPSAEEPAGLDGAEAPRSAASATGV
G
NT seq 1806 nt   +upstreamnt  +downstreamnt
atgctcgcgtgcatcctcgcccggcacggggtctcgactcttctgctggagggagcgagc
catccgcgattcaccatcggtgagtcattgataccggagaccggcctgcgactgcgaatc
gtcgccgacaagtacggcgtcccggagatcgggtggatcggcacattccacaagctacgc
aaacacgtgagcagcaattgcggtgtcaagcgctccttcggcttcatgtatcaccgcgca
ggtgaggagaaccgtcccgaggagatcaaccagttcgggacgctgacgccgcccgccgga
cccgactcgcatctgttccgccaggacaccgatgcctttctcgcggcgctctcggtcaag
tacggggcgacgttccgctcacagacgcgcatctccgacatcaccttcggagacgacgag
gtcgaactgcgcgcggcctcgggcgagacgtaccgcgccaagctcctgatcgacgcctcg
ggcatgcggtcgatggtctcggaccaactcggcatgcgcgacgaggtgccgcgcttccgc
accgacacacgcacgatctacacccacatgatgggcgtcagaagcgccgatctgctgttg
gaccccaaaggccggcgcaatctgatctcgccgctcggccagtccacgatgcaccacgtc
ttcgacggcggctggatgtgggtcatcccgttcagcaaccaccgggacgccaccaacccg
ctcaccagcgtggggctgatgctcgaccggcgcaagcaccccgatccgcaggggacgccg
gagcaggagttccgccgggtcatctccgcctacccgaccgtggcgcggcacttcgccgag
gcgaacgccgcacggccgtgggtcaggtcgggccgcatccagtactcctcgccgcacctg
atcgcgccccgtctgatccagctgccgcacgcggccgcgttcatcgacccgctctactcg
agcggtatgtcggtgctcgtcgtcgcggtcgacctgatcgccgagtcgctgctcaaggcc
gtcgcggagaacgactacgcgaccgagcgattcaagttcatggaggacgtggtcaaccgc
gggttcgaccactacgacacgatcgtgtcagggtccttcgactcgttcgcgagctacgac
acctggaacgcgtggaaccgcaactgggtgatggggagcctgctcggcacgttcggcccg
ctgtcgctgctgatgcactaccacaagacgaaggaccgctcgtacctggagaagaccacc
gagccgagccgcatgggcgtgctcggcagccacctgccgggtgtcgtcgacatggcgcgg
gcctcgcgcgcggacatggacgccgcgatcgcgggccggatcacccacaaggaggcgagc
gagcgcatcttcgcccggttccgagcgaccgacttcctgccgccctacatgggcttcggc
gatcccaggaagaccgccacggcgacgttcacgctgatccccggtgcccgccacgtcacg
tggtaccggatgcacggcgacccggtgtaccgggacaactgcaccttcccgctgatgacg
tacgcacgcgacggtgcgaccttcgtgctgggtgaggcgcgggacgcgtggcggcgcagc
ttctccgccctgcgtgacgtcttcttcgcccacaacagcgactggcgccacatcgcgccg
gcactcgctgagcacggagagctcgtgacgccggttccggcgtccgcgccctccgcggag
gaaccggccggactcgacggcgccgaggccccccggagcgcggcctcggcgaccggagtc
ggctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (30)   

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