KEGG   Sarcophilus harrisii (Tasmanian devil): 100918816
Entry
100918816         CDS       T02286                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521  EGFR tyrosine kinase inhibitor resistance
shr01522  Endocrine resistance
shr04010  MAPK signaling pathway
shr04014  Ras signaling pathway
shr04015  Rap1 signaling pathway
shr04066  HIF-1 signaling pathway
shr04068  FoxO signaling pathway
shr04114  Oocyte meiosis
shr04115  p53 signaling pathway
shr04150  mTOR signaling pathway
shr04151  PI3K-Akt signaling pathway
shr04152  AMPK signaling pathway
shr04211  Longevity regulating pathway
shr04213  Longevity regulating pathway - multiple species
shr04510  Focal adhesion
shr04550  Signaling pathways regulating pluripotency of stem cells
shr04730  Long-term depression
shr04750  Inflammatory mediator regulation of TRP channels
shr04913  Ovarian steroidogenesis
shr04914  Progesterone-mediated oocyte maturation
shr04935  Growth hormone synthesis, secretion and action
shr04960  Aldosterone-regulated sodium reabsorption
shr05200  Pathways in cancer
shr05202  Transcriptional misregulation in cancer
shr05205  Proteoglycans in cancer
shr05214  Glioma
shr05215  Prostate cancer
shr05218  Melanoma
shr05224  Breast cancer
shr05410  Hypertrophic cardiomyopathy
shr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100918816 (IGF1)
   04014 Ras signaling pathway
    100918816 (IGF1)
   04015 Rap1 signaling pathway
    100918816 (IGF1)
   04066 HIF-1 signaling pathway
    100918816 (IGF1)
   04068 FoxO signaling pathway
    100918816 (IGF1)
   04151 PI3K-Akt signaling pathway
    100918816 (IGF1)
   04152 AMPK signaling pathway
    100918816 (IGF1)
   04150 mTOR signaling pathway
    100918816 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100918816 (IGF1)
   04115 p53 signaling pathway
    100918816 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100918816 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    100918816 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100918816 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    100918816 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    100918816 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100918816 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    100918816 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100918816 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    100918816 (IGF1)
   04213 Longevity regulating pathway - multiple species
    100918816 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100918816 (IGF1)
   05202 Transcriptional misregulation in cancer
    100918816 (IGF1)
   05205 Proteoglycans in cancer
    100918816 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    100918816 (IGF1)
   05218 Melanoma
    100918816 (IGF1)
   05215 Prostate cancer
    100918816 (IGF1)
   05224 Breast cancer
    100918816 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100918816 (IGF1)
   05414 Dilated cardiomyopathy
    100918816 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100918816 (IGF1)
   01522 Endocrine resistance
    100918816 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:shr04052]
    100918816 (IGF1)
Cytokines and neuropeptides [BR:shr04052]
 Cytokines
  Growth factors (RTK binding)
   100918816 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 100918816
NCBI-ProteinID: XP_012406054
Ensembl: ENSSHAG00000008195
UniProt: A0A7N4P467
Position
5:23082882..23210676
AA seq 190 aa
MDKFNSLSTQFSKCCLCDFLKVKMHTVSSIHLFYLALCLLTLTSSATAGPETLCGAELVD
ALQFVCGERGFYFSKPTGYGSSSRRLHHTGIVDECCFRSCDLRRLEMYCAPIKPAKSARS
VRAQRHTDMPKAQKYQPPSTNKRTKAERRRKGNTFEERKQRELRKQELQNVRTTVQERRM
NTPPLRDPSL
NT seq 573 nt   +upstreamnt  +downstreamnt
atggacaaattcaacagtctttcaacccaattctctaagtgctgcctttgtgatttcttg
aaggtgaagatgcataccgtgtcctccatccatctcttctacctggccttgtgtttgctc
accttgaccagttcggccacagcggggccggagacactctgcggagctgagctggtggat
gccctgcagtttgtttgtggagaaagaggtttctacttcagcaagcccactgggtatggc
tctagcagtcggcgtttacaccacacagggatcgtggacgaatgctgcttccggagctgt
gatctgagacggctagagatgtactgtgcgccaattaagccagccaagtcagcccgctcg
gtgcgtgcccaacgccacaccgatatgcccaaagcccaaaagtatcagcccccatccacc
aacaagagaacgaaggctgagaggaggaggaaaggaaatacatttgaagaacgcaagcag
agggaactcaggaagcaggaactacagaatgtaagaactaccgtccaggagcggagaatg
aatacgcctcctctgcgggatccttctctgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (31)   
   KEGG PATHWAY (31)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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