KEGG   Sarcophilus harrisii (Tasmanian devil): 100927518
Entry
100927518         CDS       T02286                                 
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00010  Glycolysis / Gluconeogenesis
shr00020  Citrate cycle (TCA cycle)
shr00620  Pyruvate metabolism
shr00785  Lipoic acid metabolism
shr01100  Metabolic pathways
shr01200  Carbon metabolism
shr01210  2-Oxocarboxylic acid metabolism
shr04066  HIF-1 signaling pathway
shr04922  Glucagon signaling pathway
shr05230  Central carbon metabolism in cancer
shr05415  Diabetic cardiomyopathy
Module
shr_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100927518
   00020 Citrate cycle (TCA cycle)
    100927518
   00620 Pyruvate metabolism
    100927518
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    100927518
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    100927518
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100927518
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    100927518
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100927518
Enzymes [BR:shr01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     100927518
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N
Other DBs
NCBI-GeneID: 100927518
NCBI-ProteinID: XP_031792909
Ensembl: ENSSHAG00000005427
Position
4:complement(78336389..78341360)
AA seq 415 aa
MSRSVPSTAAQPSPWSRYWCSSYGSLNKMLLVVSRMMGSASPKPAGEVLLAARNFVNEAS
FDIKKCALHRLEEGPPVSAVLTREEGLKYYKIMQTVRRMELKADQLYKQKVIRGFCHLYD
GQEACCVGIEAAINPSDHVITAYRAHGFTYARGLSVREILAELTGRRGGCAKGKGGSMHM
YTKNFYGGNGIVGAQVPVGAGIALACKYKSTDEICFTLYGDGAANQGQIFETYNMAALWK
LPCVFVCENNRYGMGTSTERAAASTDYYRRGDFIPGIKVDGMDVLCVREATKFVASYARS
GKGPILMELQTYRYHGHSMSDPGVSYRSREEIKEVRNKSDPIMLHKNRMVNSKLASIEEL
KEIDIEVRKEIEDAAQFATADPEPPLEELGYHVYSGQISFDVRGVNQWIKYKSVC
NT seq 1248 nt   +upstreamnt  +downstreamnt
atgtctcgttctgtcccatccactgctgcccaaccgtcaccctggagcagatactggtgc
tccagctacggttccctgaacaaaatgctccttgtggtttctcgcatgatggggagcgcc
tccccaaaaccagctggagaagtgctgttggcagcccgtaactttgtaaatgaagcttcc
tttgatattaagaaatgtgcccttcatcgcctggaagagggccctccagtcagtgcggtt
ctcactagagaggaaggactcaagtactataagataatgcagacggtccgtaggatggaa
ctgaaagcagatcagttgtacaagcaaaaggtcatccgtggtttctgccacttgtatgac
ggtcaggaagcttgttgtgtggggatcgaggcggctataaatccttcggatcatgtgatt
acagcctatagagctcatggctttacctatgcccgtggactttctgttagagaaatttta
gctgagctaacgggacgcagaggaggctgcgccaaaggaaagggaggctcaatgcacatg
tacaccaagaacttctatggaggcaacggtattgttggagcccaagtgccagtgggagct
gggattgccctggcctgcaagtacaaatcaacagatgagatctgttttactctgtacgga
gatggtgctgctaatcagggtcagatattcgaaacttacaatatggcagctttgtggaaa
ctgccttgtgtttttgtttgtgaaaataatcgatatggaatgggaacttcgacggagaga
gcagcagccagcactgattattacagaagaggagactttattccaggaataaaagtagat
ggtatggatgttctgtgtgtccgagaagccacaaaatttgtagcttcctatgccagatca
ggaaagggccccatattgatggaactacagacatatcgttatcatggacacagcatgagt
gatcctggtgtgagttaccgttctagggaggagattaaggaagtgaggaataagagtgac
cctattatgcttcacaaaaataggatggtcaacagcaaacttgccagtattgaagaatta
aaagaaattgatattgaagtaaggaaagagattgaagatgctgcccagtttgctacagct
gatccagagccacctttggaagaattaggttatcatgtctactctggacagatatctttt
gatgttcgaggtgtgaatcaatggatcaagtacaaatctgtctgctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (12)   
   KEGG PATHWAY (11)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (59)   

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