KEGG   Sarcophilus harrisii (Tasmanian devil): 105750762
Entry
105750762         CDS       T02286                                 
Symbol
IL6
Name
(RefSeq) interleukin-6
  KO
K05405  interleukin 6
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521  EGFR tyrosine kinase inhibitor resistance
shr01523  Antifolate resistance
shr04060  Cytokine-cytokine receptor interaction
shr04061  Viral protein interaction with cytokine and cytokine receptor
shr04066  HIF-1 signaling pathway
shr04068  FoxO signaling pathway
shr04151  PI3K-Akt signaling pathway
shr04218  Cellular senescence
shr04620  Toll-like receptor signaling pathway
shr04621  NOD-like receptor signaling pathway
shr04623  Cytosolic DNA-sensing pathway
shr04625  C-type lectin receptor signaling pathway
shr04630  JAK-STAT signaling pathway
shr04640  Hematopoietic cell lineage
shr04657  IL-17 signaling pathway
shr04659  Th17 cell differentiation
shr04668  TNF signaling pathway
shr04672  Intestinal immune network for IgA production
shr04931  Insulin resistance
shr04932  Non-alcoholic fatty liver disease
shr04933  AGE-RAGE signaling pathway in diabetic complications
shr04936  Alcoholic liver disease
shr05010  Alzheimer disease
shr05020  Prion disease
shr05022  Pathways of neurodegeneration - multiple diseases
shr05132  Salmonella infection
shr05133  Pertussis
shr05134  Legionellosis
shr05135  Yersinia infection
shr05142  Chagas disease
shr05143  African trypanosomiasis
shr05144  Malaria
shr05146  Amoebiasis
shr05152  Tuberculosis
shr05161  Hepatitis B
shr05162  Measles
shr05163  Human cytomegalovirus infection
shr05164  Influenza A
shr05166  Human T-cell leukemia virus 1 infection
shr05167  Kaposi sarcoma-associated herpesvirus infection
shr05168  Herpes simplex virus 1 infection
shr05169  Epstein-Barr virus infection
shr05171  Coronavirus disease - COVID-19
shr05200  Pathways in cancer
shr05202  Transcriptional misregulation in cancer
shr05321  Inflammatory bowel disease
shr05323  Rheumatoid arthritis
shr05332  Graft-versus-host disease
shr05410  Hypertrophic cardiomyopathy
shr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    105750762 (IL6)
   04668 TNF signaling pathway
    105750762 (IL6)
   04066 HIF-1 signaling pathway
    105750762 (IL6)
   04068 FoxO signaling pathway
    105750762 (IL6)
   04151 PI3K-Akt signaling pathway
    105750762 (IL6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    105750762 (IL6)
   04061 Viral protein interaction with cytokine and cytokine receptor
    105750762 (IL6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105750762 (IL6)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    105750762 (IL6)
   04620 Toll-like receptor signaling pathway
    105750762 (IL6)
   04621 NOD-like receptor signaling pathway
    105750762 (IL6)
   04623 Cytosolic DNA-sensing pathway
    105750762 (IL6)
   04625 C-type lectin receptor signaling pathway
    105750762 (IL6)
   04659 Th17 cell differentiation
    105750762 (IL6)
   04657 IL-17 signaling pathway
    105750762 (IL6)
   04672 Intestinal immune network for IgA production
    105750762 (IL6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105750762 (IL6)
   05202 Transcriptional misregulation in cancer
    105750762 (IL6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105750762 (IL6)
   05161 Hepatitis B
    105750762 (IL6)
   05171 Coronavirus disease - COVID-19
    105750762 (IL6)
   05164 Influenza A
    105750762 (IL6)
   05162 Measles
    105750762 (IL6)
   05168 Herpes simplex virus 1 infection
    105750762 (IL6)
   05163 Human cytomegalovirus infection
    105750762 (IL6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105750762 (IL6)
   05169 Epstein-Barr virus infection
    105750762 (IL6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105750762 (IL6)
   05135 Yersinia infection
    105750762 (IL6)
   05133 Pertussis
    105750762 (IL6)
   05134 Legionellosis
    105750762 (IL6)
   05152 Tuberculosis
    105750762 (IL6)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105750762 (IL6)
   05144 Malaria
    105750762 (IL6)
   05142 Chagas disease
    105750762 (IL6)
   05143 African trypanosomiasis
    105750762 (IL6)
  09163 Immune disease
   05323 Rheumatoid arthritis
    105750762 (IL6)
   05321 Inflammatory bowel disease
    105750762 (IL6)
   05332 Graft-versus-host disease
    105750762 (IL6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105750762 (IL6)
   05020 Prion disease
    105750762 (IL6)
   05022 Pathways of neurodegeneration - multiple diseases
    105750762 (IL6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105750762 (IL6)
   05410 Hypertrophic cardiomyopathy
    105750762 (IL6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105750762 (IL6)
   04932 Non-alcoholic fatty liver disease
    105750762 (IL6)
   04931 Insulin resistance
    105750762 (IL6)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105750762 (IL6)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105750762 (IL6)
   01523 Antifolate resistance
    105750762 (IL6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:shr04052]
    105750762 (IL6)
Cytokines and neuropeptides [BR:shr04052]
 Cytokines
  Interleukins
   105750762 (IL6)
SSDB
Motif
Pfam: IL6 GCSF Glyco_hydro_85 DUF5775 DUF2887
Other DBs
NCBI-GeneID: 105750762
NCBI-ProteinID: XP_031796496
Position
5:complement(275542528..275548261)
AA seq 215 aa
MGPQLQITGSLGPLAFTLVLLVTTAARPTPDALGVSSKPALGTTDLGKCKSLAKTLYKEA
DALKEENGENQSMCDNSSTILAENNLVFPNLTEQDGCFYSGFNKETCLINLISKLQEFDG
YFQFMENELKEKKSRIEALKMFTTQLAESLKKLMMGADLVPTLNPTASHDLVLKLKSLNE
WSRKVALHLSLCRYIKFMEHTIRAIRNMDPTDVSV
NT seq 648 nt   +upstreamnt  +downstreamnt
atgggccctcagctccagatcacagggtccctcgggccgctggccttcaccctggtgctg
ctcgtcaccacggccgcccgccccaccccggacgccttgggggtctccagcaagccagca
ttgggcactaccgacctgggcaaatgcaagagcctagccaaaacgctgtacaaagaagct
gacgccctgaaggaagagaatggtgaaaaccagagcatgtgcgacaatagcagcaccata
ctagctgaaaacaacctggtctttcccaacttgacagagcaagatggatgcttctattct
ggattcaataaggagacatgcctgataaacctcatcagtaaactgcaggaatttgacggg
tatttccagttcatggaaaatgagctgaaagaaaagaaaagcaggatcgaagcactaaaa
atgttcacgactcaactagccgagtctctgaaaaaattgatgatgggggcagatctagta
ccaaccctcaacccaactgcctcccatgacctggttttgaaactgaagagcctgaatgag
tggtccaggaaggtggctctccatctcagcctgtgtcgctacatcaagttcatggagcat
accattcgggctattcggaacatggaccccacggatgtcagtgtttga

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