KEGG   Sulfolobus islandicus M.14.25: M1425_1999
Entry
M1425_1999        CDS       T00890                                 
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sia  Sulfolobus islandicus M.14.25
Pathway
sia00290  Valine, leucine and isoleucine biosynthesis
sia00620  Pyruvate metabolism
sia01100  Metabolic pathways
sia01110  Biosynthesis of secondary metabolites
sia01210  2-Oxocarboxylic acid metabolism
sia01230  Biosynthesis of amino acids
Module
sia_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sia00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    M1425_1999
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    M1425_1999
Enzymes [BR:sia01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     M1425_1999
SSDB
Motif
Pfam: HMGL-like LeuA_dimer PEP_mutase
Other DBs
NCBI-ProteinID: ACP38740
UniProt: C3MYV6
Position
1831092..1832741
AA seq 549 aa
MKYDFFPLSLKLLNLPIIFHLCSVSKKSVEVLDTTLRDGSQGANISFTLNDKIKIALLLD
ELGVEYIEGGWPGSNPKDEEFFKEIKKYKLSKARIAAFGSTKRKDVSVKEDISLNSIIKA
DVDFAVIFGKSWSLHATEVLKVTKQDNLDIIYDSINYLRSHGLKVIFDAEHFYQGFKEDP
KYALEVVKTAESAGADVIALADTNGGTPPFEVYEITKKVREVLHVKLGIHAHNDIGCAVA
NSLMAIKAGARHVQGTINGIGERTGNADLIQIIPTLVLKMGFNVLKGRDSLRKLREVSRI
VYEILGLPPNPYQPYVGDNAFAHKAGVHVDAVMKVPRAYEHVDPLLVGNDRKFVISELSG
TANLVSYLQGIGIVVDKKDERLKKALNKIKELEAKGYSFDVGPASAILITLKELNMYTNY
INLEYWKVINENNGLSIGIVKVNSQLEVAEGVGPVNAIDRALRMALQRVYPEIGEVKLID
YRVILPSEVKNTESVVRVTIEFTDNKMNWRTEGVSKSVVEASVMALVDGLDYYLQLKKIL
KTSADNYIA
NT seq 1650 nt   +upstreamnt  +downstreamnt
atgaaatatgattttttcccattatcattaaagcttttaaatcttcccattatttttcac
ctatgttcggtgtccaagaaatctgttgaggttctagatacaacattaagagatggatcg
cagggcgcgaatatatcttttactctaaatgataaaattaagatagcattactcttagat
gagcttggagtagaatatattgaaggaggatggccaggatctaatcctaaggatgaggag
ttctttaaagagataaagaaatataaactatctaaagctagaatagctgcctttggaagt
accaaaagaaaagatgttagcgtaaaggaagatattagtctaaatagtataataaaagca
gatgttgattttgctgtaatatttggtaagtcatggtcactacatgctactgaagtccta
aaggtaactaagcaagataatttagatataatatatgacagcattaattatttgagatca
catggtcttaaggtgatatttgatgcagagcacttctatcaaggctttaaagaagatcca
aaatatgcactcgaagtagtgaaaactgcagaatctgcgggggcagatgtaattgcttta
gcagatactaatggtggtacaccaccatttgaggtttatgagataacaaagaaagttaga
gaagtattacatgttaaactaggtattcatgcccataatgatataggatgtgcagttgcc
aactctttaatggctataaaagcaggagctaggcatgtccaaggaacaataaatggaatt
ggcgagagaactggtaatgctgatctaatacagataatacccacattagtgttaaaaatg
ggatttaatgtattaaaaggtagagatagtttaaggaaattgagggaggtttcaagaata
gtatatgaaatactaggattacctcctaatccctatcaaccttatgttggtgataacgcc
ttcgcacacaaagctggtgttcatgttgatgctgtaatgaaggtacccagagcgtatgaa
catgttgatcctttattagtaggtaatgacagaaagtttgtaatttcagaattgtctgga
actgcaaatctagtctcatatttacaaggcataggaatagttgttgacaagaaagacgaa
aggcttaaaaaagctttaaataagattaaggaacttgaggctaaaggatatagttttgat
gttggtccagcttccgcaattttgataacactaaaggagctaaacatgtatacgaattat
ataaatttagaatactggaaagtaataaacgagaataatggtctttcaatagggatcgtt
aaagttaattctcagctcgaagttgctgaaggggtaggtccagtaaacgcaatagataga
gcgctaagaatggcacttcagcgggtatatccagaaataggtgaagttaagttaatagat
tatagggttatattgcctagtgaagttaagaacactgagagtgtcgttagggttaccata
gaatttacagataataaaatgaactggagaacagaaggagtatctaaaagcgttgtggaa
gcttcagtcatggcattagtagatgggcttgattattacctacaattaaagaagatatta
aaaacaagtgcagataattatattgcgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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