KEGG   Sugiyamaella lignohabitans: AWJ20_1713
Entry
AWJ20_1713        CDS       T05270                                 
Symbol
MIS1
Name
(RefSeq) trifunctional formate-tetrahydrofolate ligase
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
slb  Sugiyamaella lignohabitans
Pathway
slb00670  One carbon pool by folate
slb01100  Metabolic pathways
slb01240  Biosynthesis of cofactors
Module
slb_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:slb00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    AWJ20_1713 (MIS1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:slb04147]
    AWJ20_1713 (MIS1)
Enzymes [BR:slb01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     AWJ20_1713 (MIS1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     AWJ20_1713 (MIS1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     AWJ20_1713 (MIS1)
Exosome [BR:slb04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   AWJ20_1713 (MIS1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C HEM4 OCD_Mu_crystall
Other DBs
NCBI-GeneID: 30033546
NCBI-ProteinID: XP_018735899
UniProt: A0A167DXR6
Position
A:5229871..5232810
AA seq 979 aa
MLRQLKPWRASLAVRLPTSSAWSQSSRAALLSSRSFSSNSVLYDADKIDGNAIAKSIRQE
IQKEITEIKRVKPQFNPNLVIIQVGDRPDSSAYVRMKLKAAHEAKLSCELRKFPDSITEA
QLLEEIEDLNDDTSVHGILVQLPLPKEINEGRITDAVSIDKDVDGFGTLNIGELSRRGGS
PLFVPCTPKGVMVLLEKHKVELRGKNAVVIGRSDIVGTPVASLLRAADATVTVCHRYTQD
LASIVKQADVVIAAVGVPDFVKGEWLKPGAVVIDVGINYVPDETKKSGKRLTGDVDYASS
AKVASLITPVPGGVGPMTVAMLVQNVVDSAKRHYQEQERRHVTPLPLRLQKPVPSDIDIS
RSQHPKKIRDLAKEVGITDHELIPYGAYKGKVSLHALKRLEHRKDGKYILVAGITPTPLG
EGKSTTTMGLAQALGGHLGKMAFANVRQPSMGPTFGIKGGAAGGGYAQVIPMDEFNMHLT
GDIHAISAANNLLAAAIDTRMFHEKSQKDASLYKRLVPKNKFTPSMLKRLKKLGIDKTDP
ASLTKEEIRKFARLDIDPDTITWKRVVDCNDRHLRTITVGEAPTEKGDIRQTGFDITVAS
ECMAVLALSNSLHDMRERLGNMVVASSRDGVPITCDDLGAGGALTALMKDAIMPNLMQTL
EGTPVLVHAGPFANISIGASSVLADKIALKLVGSEPGENHEEKAGYVITEAGFDFTMGGE
RFFNIKCRSSGLVPDTVVIVATVRALKLHGGGPDVKPGQKLPDAYLNANVDLVRNGCSNL
KKQIQNAKSYGVPVVVAINRFSSDSAEEIEIIREEALAAGANDAIASNHWEEGGLGAIDL
AKGVIKAANEGSHDDFKLLYDIPNTSAEDKLNIIAREMYGAEKVELSPLAREKIERYTKQ
GFGNLPICIAKTQYSLSHDPNLKGVPSGFTVPIRDVRASVGAGYLYALAAEIMTIPGLPT
YAGFMNVEVDDEGNIDGLF
NT seq 2940 nt   +upstreamnt  +downstreamnt
atgctgagacagctaaaaccatggcgggcctcattggctgttaggcttccaacctcatcg
gcttggtcgcagtcgtcaagagctgctctattatctagtcgctcattctcttctaactct
gtcctctatgatgccgataagatcgatggtaacgccattgctaaatctattcgtcaggag
atccagaaagaaatcactgaaattaaaagagttaagcctcaatttaatcccaatttggtg
attattcaagttggagacagacctgattcttcagcttatgttcgcatgaagttaaaggct
gcccatgaagctaaactttcctgcgaattgagaaagttcccagatagcatcaccgaagct
cagcttttggaagagattgaggatcttaatgatgataccagtgtccatggtatcttggtt
caactgcccctgcccaaggaaatcaatgagggccggattactgatgctgtgtccattgat
aaggatgtggatgggtttggcactttaaatattggcgaattatcccgtcgtggaggatct
cctctatttgtcccttgtacccctaaaggtgtaatggttctgcttgaaaagcacaaagtt
gaacttcgtggtaagaacgccgtcgtcatcggtagatctgatattgtcggtacccctgtt
gccagtcttttgagagccgccgatgccactgtcacagtctgtcatagatacacccaagac
ttggcttccatcgtaaagcaagctgatgttgttattgcagccgttggagtgcctgatttt
gtcaagggagaatggctcaagcccggtgctgtagtcattgacgttggtatcaattatgtg
ccagacgagacgaaaaagtcgggaaaaagactgactggtgatgttgactatgcatcttct
gctaaggttgcttcgcttattactcctgttcctggtggagttggccccatgactgttgct
atgctggtgcaaaatgtggttgattctgctaaacgtcactaccaagagcaagagagacgt
cacgttactccattgcctcttcgattacaaaaaccagtcccctcggatattgacatctcg
agatctcaacaccccaagaaaatccgtgacttagccaaggaagttggtatcactgatcat
gagcttatcccttacggagcttacaagggcaaggtgagtcttcacgctttgaagagattg
gaacaccgcaaagatggtaaatatattcttgttgctggtatcactcccactcctcttggt
gaaggcaagtctaccaccacaatgggtctcgcccaagcccttggcggccatttgggtaaa
atggcttttgcaaatgttcgtcaaccctcaatgggaccaacatttggtatcaaaggtggt
gctgccggtggtggttacgctcaagtcatccccatggacgagttcaatatgcatttaact
ggtgatatccacgccatctctgctgctaataacttgcttgctgcagctatcgatactcgc
atgttccacgagaaatctcaaaaggacgcatctctatataagagattggttcctaaaaat
aagtttactccttcaatgttgaaaagattgaagaagcttggaatagacaagaccgaccct
gccagtttgaccaaggaggagattcgcaagtttgctcgtctcgacatcgaccctgatacc
attacatggaagcgtgtcgtagactgtaatgatagacatttgcgcactattacagttgga
gaggcacccactgaaaagggtgatattcgacaaactggtttcgacatcacagtcgctagt
gaatgcatggctgtgcttgccctttcaaacagtcttcacgatatgagagaacgtcttgga
aacatggtagtggctagtagccgggacggtgttccaattacttgtgatgaccttggagcc
ggcggtgctttgactgctttgatgaaagacgctatcatgcctaatctcatgcagaccctt
gagggtactcctgttcttgtacatgccggtccatttgctaatatcagcattggagccagt
tcggttcttgccgataagattgctctcaagctggttggatctgagcctggtgagaatcac
gaagagaaggctggttatgtaattactgaagcaggttttgattttactatgggaggtgaa
cgttttttcaatatcaagtgtagatccagtgggctggttcctgatactgttgttattgta
gcaaccgttcgtgcacttaagttacatggtggcggtcccgatgtcaagcctggtcagaaa
ctgccagatgcttatttgaatgccaatgtcgacttggttagaaacggttgttctaatctt
aagaagcaaatccaaaatgccaagagttacggtgtgccagtagtggttgctattaacaga
ttctcttctgatagtgccgaagagattgaaattattcgcgaggaagccttggctgctggt
gccaatgatgctattgcttctaaccactgggaagagggtggactgggtgccattgatctt
gctaagggagttatcaaggcagccaatgaaggcagtcatgatgatttcaagttactctat
gatatccccaatacttctgctgaagacaagctgaacatcattgccagagaaatgtacggt
gcagagaaggttgaactgagccccttggcacgtgaaaagattgagcgctacaccaagcag
ggatttggcaacttgcccatctgtattgccaagactcaatactcgctatcccatgatcct
aacttgaagggtgtcccctctggtttcactgtacctatccgtgatgttcgtgcctcggtt
ggtgccggatatttatacgcacttgctgctgagattatgaccatccctggtttgcccact
tatgccggattcatgaacgtcgaggttgatgatgagggcaacattgatggactcttttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (47)   

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