KEGG   Streptomyces avermitilis: SAVERM_2685
Entry
SAVERM_2685       CDS       T00126                                 

Gene name
leuD
Definition
(GenBank) putative 3-isopropylmalate dehydratase subunit small
  KO
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
Organism
sma  Streptomyces avermitilis
Pathway
sma00290  Valine, leucine and isoleucine biosynthesis
sma00660  C5-Branched dibasic acid metabolism
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
sma01210  2-Oxocarboxylic acid metabolism
sma01230  Biosynthesis of amino acids
Module
sma_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SAVERM_2685 (leuD)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SAVERM_2685 (leuD)
Enzymes [BR:sma01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SAVERM_2685 (leuD)
    4.2.1.35  (R)-2-methylmalate dehydratase
     SAVERM_2685 (leuD)
SSDB
Motif
Pfam: Aconitase_C FAD_syn
Other DBs
NCBI-ProteinID: BAC70396
NITE: SAV2685
UniProt: Q82JR9
Position
complement(3290964..3291557)
AA seq 197 aa
MEAFTTHTGRAVPLRRSNVDTDQIIPAHWLKKVTRDGFEDGLFEAWRKDESFILNRPERT
GATVLVAGPDFGTGSSREHAVWALQNYGFKAVISSRFADIFRGNSLKNGLLTVVLEQKIV
DALWELTEKDPQAEVTVDLEAREVRAEGITAAFELDENARWRLLNGLDDISITLQNEGDI
ATYEAKRPSHKPRTLQV
NT seq 594 nt   +upstreamnt  +downstreamnt
atggaagcattcaccacgcacaccggccgggccgtcccgctgcgccgcagcaacgtcgac
accgaccagatcatccccgcccactggctcaagaaggtcaccagggacggtttcgaggac
gggctgttcgaggcctggcgcaaggacgagtccttcatcctcaaccggcccgagcgcacg
ggtgccacggtcctggtcgccggccccgacttcggtacgggttcctcgcgcgagcacgcc
gtgtgggcgctccagaactacggcttcaaggccgtcatctcctcgcgcttcgccgacatc
ttccgcggcaactcgctcaagaacggcctgctcacagtggttctggagcagaagatcgtg
gacgcgctgtgggaactcaccgaaaaggacccgcaggccgaggtcacggtcgacctggag
gcccgtgaggtgcgcgccgagggcatcacggcggccttcgagctcgacgagaacgcccgt
tggcggctgctgaacggcctggacgacatctccatcaccctccagaacgagggcgacatc
gcgacgtacgaggccaagcggccgtcgcacaagccgcggacgctccaggtctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NITE (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (33)   

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KEGG   Streptomyces avermitilis: SAVERM_2686
Entry
SAVERM_2686       CDS       T00126                                 

Gene name
leuC
Definition
(GenBank) putative 3-isopropylmalate dehydratase subunit large
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
sma  Streptomyces avermitilis
Pathway
sma00290  Valine, leucine and isoleucine biosynthesis
sma00660  C5-Branched dibasic acid metabolism
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
sma01210  2-Oxocarboxylic acid metabolism
sma01230  Biosynthesis of amino acids
Module
sma_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SAVERM_2686 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SAVERM_2686 (leuC)
Enzymes [BR:sma01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SAVERM_2686 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     SAVERM_2686 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: BAC70397
NITE: SAV2686
UniProt: Q82JR8
Position
complement(3291564..3292997)
AA seq 477 aa
MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRAHAPEGEEWDAAVAYWKTLKSDEDAEFDAEVVIAAAALSPFVTWGTNPGQGAPL
SASVPDPASYEDASERFAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAA
IVEGRKVADGVRMLIVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLADENAARTPAGV
NT seq 1434 nt   +upstreamnt  +downstreamnt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagtccgcaggcc
ttcgacggtctgcgccaggcggggcgtccggtgcgccgtctcgacctcaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgcggacccggtctcccgg
gcccagctggagacgctgcgcaagaactgcgccgagttcggcgtgcgcctgcactcgctc
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctgggcctgacccagccc
ggcaccacggtcgtctgcggcgactcccacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcacctcgcaggtcgagcacgtgctggccacccagacgctgccgctg
gcccgccccaagaccatggccatcaccgtcgacggcgagctgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaggatcggtaccggcggcggccagggctacatc
ctggaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctcaagggccgtgcccacgcgcccgagggcgaggagtgggacgccgccgtcgcg
tactggaagaccctgaagtcggacgaggacgcggaattcgacgccgaggtcgtcatcgcc
gccgccgcgctgtcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcgtccgtccccgaccccgcttcgtacgaggacgcttcggagcgcttcgccgccgaa
aaggccctggaatacatggggttgaccgccgggcagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgtgcggccgccgcg
atcgtcgagggccgcaaagtcgccgacggcgtacggatgctgatcgtccccggctcggcg
cgggtcggtctccaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgaaggcaggcagggcaagggcggc
cgtacgcacctggtgtcgccgcaggtcgccgccgccaccgccgtgctcggccacctggcc
tccccggccgacctggccgacgagaacgccgcccgtacgcccgctggagtctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NITE (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (1)   
   Pfam (1)   
All databases (50)   

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