KEGG   Streptomyces avermitilis: SAVERM_5342
Entry
SAVERM_5342       CDS       T00126                                 
Symbol
iolA
Name
(GenBank) putative methylmalonic acid semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
sma  Streptomyces avermitilis
Pathway
sma00280  Valine, leucine and isoleucine degradation
sma00410  beta-Alanine metabolism
sma00562  Inositol phosphate metabolism
sma00640  Propanoate metabolism
sma01100  Metabolic pathways
sma01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    SAVERM_5342 (iolA)
   00562 Inositol phosphate metabolism
    SAVERM_5342 (iolA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    SAVERM_5342 (iolA)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    SAVERM_5342 (iolA)
Enzymes [BR:sma01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     SAVERM_5342 (iolA)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     SAVERM_5342 (iolA)
SSDB
Motif
Pfam: Aldedh LuxC
Other DBs
NCBI-ProteinID: BAC73054
NITE: SAV5342
UniProt: Q82CK3
Position
6474502..6476004
AA seq 500 aa
MTKIVNHWIGGKTVEGASGTYGPVTDPATGAVTTKVAFATVDEVDAAVAAAKDAYATWGQ
SSLAKRSTILFKFRALLDANRDAIAELITAEHGKVHSDALGEVARGLEIVDLACGITVQL
KGELSTEVASRVDVSSIRQPLGVVAGITPFNFPAMVPMWMFPLAIACGNTFVLKPSEKDP
SAALKLAELLAEAGLPDGVFNVVHGDKVAVDRLLEHPDVKAVSFVGSTPIARYIHTTASA
KGKRVQALGGAKNHMLVLPDADLDAAADAAVSAAYGSAGERCMAISAVVAVGAIGDELVE
KIRERAEKIKIGPGNDPASEMGPLITKAHRDKVASYVAGAAAQGSEVVLDGTGHTVDGFE
DGHWIGLSLLDKVPTSADAYRDEIFGPVLCVLRVDSYEEGLALINDSPFGNGTAIFTRDG
GAARRFQLEVEAGMVGVNVPIPVPVGYHSFGGWKDSLFGDHHIYGNDGTHFYTRGKVVTT
RWPDPSEAPAGVDLGFPRNH
NT seq 1503 nt   +upstreamnt  +downstreamnt
atgacgaagatcgtcaaccactggatcggcggcaagaccgtcgaaggcgcgtcgggcacg
tacgggccggtcaccgacccggcgaccggcgcggtcaccacgaaggtcgccttcgcgacg
gtcgacgaggtggacgccgcggtcgccgccgcgaaggacgcctacgcgacctggggccag
tcctcgctggccaagcggagcacgatcctcttcaagttccgggcgctgctcgacgccaac
cgggacgcgatcgccgagctgatcaccgcagagcacggcaaggtgcactccgacgcgctc
ggcgaggtcgcgcgcgggctggagatcgtcgacctggcgtgcggcatcaccgtgcagctg
aagggcgagctgtcgaccgaggtcgccagccgggtggacgtctcgtcgatccggcagccg
ctgggtgtcgtcgcgggcatcacgccgttcaacttcccggccatggtgccgatgtggatg
ttcccgctcgccatcgcgtgcggcaacacgttcgtgctgaagccgtccgagaaggacccg
tcggcggccctgaagctggccgagctgctggccgaggccggtctgccggacggcgtcttc
aacgtcgtacacggggacaaggtcgcggtcgaccgcctcctggagcacccggacgtcaag
gcggtgtccttcgtcggctcgacgccgatcgcccgctacatccacacgaccgcctccgcg
aagggcaagcgtgtccaggcgctcggcggcgccaagaaccacatgctggtcctcccggac
gcggacctggacgcggccgccgacgccgccgtctcggccgcgtacggctcggccggcgag
cgctgcatggcgatctccgcggtcgtcgcggtgggcgccatcggggacgagctggtggag
aagatccgcgagcgcgccgagaagatcaagatcggtccgggcaacgacccggcctccgag
atgggtccgctgatcaccaaggcgcaccgcgacaaggtggcctcgtatgtggcgggcgcg
gcggcgcagggctccgaggtcgtcctcgacggcacgggccacacggtcgacggcttcgag
gacggccactggatcggcctctcgctgctcgataaggtgccgacgtccgcggacgcgtac
cgggacgagatcttcggcccggtgctgtgcgtgctgcgcgtggactcgtacgaggagggc
ctcgccctcatcaacgactcgccgttcggcaacggcaccgcgatcttcacccgggacggc
ggcgccgcccgccgcttccagctggaggtcgaggcgggcatggtcggtgtgaacgtgccg
attccggtgccggtgggctaccactccttcgggggctggaaggactcgctcttcggcgac
caccacatctacggcaacgacggcacgcacttctacacccgcggcaaggtcgtcaccacc
cgctggccggacccgtccgaggccccggcgggcgtcgacctgggcttcccgcgcaaccac
tga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NITE (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (35)   

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