KEGG   Streptomyces malaysiensis: SMALA_2106
Entry
SMALA_2106        CDS       T05189                                 
Name
(GenBank) pyruvate dehydrogenase subunit E1
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
smal  Streptomyces malaysiensis
Pathway
smal00010  Glycolysis / Gluconeogenesis
smal00020  Citrate cycle (TCA cycle)
smal00620  Pyruvate metabolism
smal00785  Lipoic acid metabolism
smal01100  Metabolic pathways
smal01110  Biosynthesis of secondary metabolites
smal01120  Microbial metabolism in diverse environments
smal01200  Carbon metabolism
smal01210  2-Oxocarboxylic acid metabolism
Module
smal_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:smal00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    SMALA_2106
   00020 Citrate cycle (TCA cycle)
    SMALA_2106
   00620 Pyruvate metabolism
    SMALA_2106
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    SMALA_2106
Enzymes [BR:smal01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     SMALA_2106
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N DUF3135 Transketolase_C
Other DBs
NCBI-ProteinID: ATL82340
UniProt: A0A291SND4
Position
2747365..2750040
AA seq 891 aa
MTDLVRTQPSALDQLPDRDPEETAEWGASLDAVARAAGSHRASYLMRRTLERAESAGLAL
PPLLESDYLNTIPTAAEPAFPGDEAMERRITAWNRWNAAAMVTRGSRDGLGGHIATFASA
AWLYETGFQHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRLTERHLDHFRREAGGEG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLAARGIKDTANSHVWAFLGDGEM
DEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWNVVKSL
WGSAWDELFAQDTTGALVRRLREVPDGQFQTYATRDAAYIREHFFGAEPELARLAQGFTD
AKLAECFHTSRAGHEPRKVYAAYRAAMAHKGAPTVVLAQTVKGWTLGPGFESRNANHQMK
KLTGKEFRAMRDLLELPIPDSKLDEHLVPYVHPGPDSPEVRYLQERRAALGGPAPARRVH
PVALPEPSAKPFETLAKGSGSQEIATTMAFVRLVKDLMREKETGRRWVPIVPDEARTFGM
ESLFPTAGIYSPLGQTYDPVDRDQLLYYKEAANGQILNEGITESGSMADFTAAATSYATH
GEPMIPFYIFYSMFGWQRTADQMWALADQLGRGFLIGATAGRTTMTGEGLQHADGHSPLI
ASTNPAALAYDPAFAYEVGAIVREGLRRMYGPEAEDVFYYLTVYNEPKVQPSMPTGEGVE
EGILKGLYRYREATAPAADSPRIQLLASGTAIHWTLEAQKLLADDWGVAADVWSATSWSE
LRRDALSCDAAQLNGEDRVPYVTRALAGAPGPVLAVSDWMRAVPDQISQWVEQDWYSLGT
DGFGLSDTREAARRHFGVDAPAIVVAALSRLARQGAVPATAPKEAAERYGI
NT seq 2676 nt   +upstreamnt  +downstreamnt
atgaccgatctcgtacgcacgcagccgagtgcgctcgaccagcttcccgaccgtgacccc
gaggagaccgccgaatggggcgcctccctggacgccgtcgcgcgggcggccgggtcacac
cgcgcctcgtacctcatgcgccgcaccctggagcgcgccgagagcgccgggctcgcgctg
ccgcccctgctggagtcggactacctcaacaccatcccgaccgccgccgagcccgcgttc
ccgggcgacgaggccatggagcgccgcatcaccgcctggaaccggtggaacgcggcggcg
atggtcacccgcggcagccgtgacggcctcggcggccacatcgccaccttcgcctccgcc
gcctggctctacgagacgggcttccagcacttcttccgcggcaaggaggcggacggcagc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacgggcggctgaccgagcgccatctggaccacttccgccgcgaggcgggcggcgagggc
ctgccgtcctatccgcatccgcggcggctgccgtggctgtgggagttccccaccgtctcg
atggggctcggcccgatctccgcgatctaccaggcccgtttcaaccgctatctggcggcc
cgtggcatcaaggacaccgccaactcccacgtctgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggccgcgctcgccctggccggccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtgcgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcgcggcgggctggaacgtggtcaagtccctg
tggggctccgcctgggacgagctgttcgcgcaggacaccacgggcgcgctggtgcgccgg
ctgcgcgaggtcccggacggccagttccagacgtacgcgacccgcgacgcggcctatatc
cgcgagcacttcttcggcgccgagccggagctggcccggctcgcccaggggttcaccgac
gccaagctggccgagtgtttccacacctcgcgcgcgggccatgagccccgcaaggtgtac
gcggcctaccgcgcggccatggcgcacaagggcgccccgaccgtggtgctcgcccagacc
gtcaagggctggacgctgggccccggcttcgagtcgcgcaacgccaaccaccagatgaag
aagctgacgggcaaggagttccgcgccatgcgggacctcctcgaactccccatcccggac
agcaagctggacgagcacctcgtcccctacgtccaccccggccccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggcccggccccggcccgcagggtccac
ccggtggccctgcccgagccgtccgcgaagccgttcgagacgctcgccaagggctccggc
agccaggagatcgccaccaccatggccttcgtccggctggtcaaggacctgatgcgggag
aaggagaccgggcggcgctgggtgccgatcgtgccggacgaggcacggaccttcggcatg
gagtcgctcttccccaccgccgggatctactccccgctcggccagacctacgacccggtc
gaccgcgatcagctcctgtactacaaggaggccgcgaacggtcagatcctcaacgagggg
atcaccgagtccggttcgatggccgacttcaccgccgccgcgacgtcgtacgcgacccac
ggcgagccgatgatccccttctacatcttctactcgatgttcggctggcagcgcaccgcc
gaccagatgtgggcgctcgccgaccagctcggccgcggcttcctcatcggcgccaccgcc
ggccgtacgacgatgaccggcgagggcctccagcacgccgacggccactccccgctgatc
gcctccaccaacccggcggcgctcgcctacgacccggccttcgcctacgaggtcggcgcg
atcgtgcgggagggtctgcggcggatgtacggccccgaggccgaggacgtcttctactac
ctgacggtctacaacgagcccaaggtccagccgtcgatgcccacgggcgagggcgtcgag
gagggcatcctcaagggcctgtaccgctaccgggaggccacggccccggccgcggactcc
cctcgtatccagctgctcgcctccggcaccgccatccactggacgctggaggcccagaaa
ctcctcgccgacgactggggcgtggccgccgacgtgtggtccgccacctcctggagcgag
ctgcgccgcgacgccctgtcctgtgacgcggcgcagctcaacggcgaagaccgggtcccg
tacgtcacccgtgccctggcaggcgcaccgggcccggtcctcgccgtcagcgactggatg
cgtgccgtccccgaccagatcagccagtgggtcgagcaggactggtactcactgggcacg
gacggcttcggcctctccgacacccgcgaggccgcccgccgccacttcggcgtggatgcc
ccggccatcgtggtggccgcactgtcccggctggcccgccaaggcgcggtcccggccacc
gcgcccaaggaagccgcggagcggtacggcatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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