KEGG   Streptomyces malaysiensis: SMALA_8367
Entry
SMALA_8367        CDS       T05189                                 
Name
(GenBank) isopropylmalate isomerase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
smal  Streptomyces malaysiensis
Pathway
smal00290  Valine, leucine and isoleucine biosynthesis
smal00660  C5-Branched dibasic acid metabolism
smal01100  Metabolic pathways
smal01110  Biosynthesis of secondary metabolites
smal01210  2-Oxocarboxylic acid metabolism
smal01230  Biosynthesis of amino acids
Module
smal_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:smal00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SMALA_8367
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SMALA_8367
Enzymes [BR:smal01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SMALA_8367
    4.2.1.35  (R)-2-methylmalate dehydratase
     SMALA_8367
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: ATL88576
UniProt: A0A291T606
Position
complement(10513411..10514886)
AA seq 491 aa
MAKTLYDKVFDLHAVRELGDGQYQLFVGLHLVHEATSPQAFSMLRERGLKVAYPERNIAT
ADHVIPTDTVLRPYTDELGEAMLSELERNTGAFGLRFLSPDRGEHGIVHVVGPERGLTQP
GMTIVCGDSHTTTHGAFGAVALGIGTSQVRDVLATQTVVVNRLKVRRVQIDGALGAGVAA
KDVILYVIHRLGVMGGVGYAYEFAGEVVDRMSMDERMTLCNMAVEGGARCGYVNPDETTF
AALRGRPNAPAGADWDRAVAWWRSVASDPDAPYDDVVRLDGAAIPPMVTWGINPGQAVPV
DGAVPSDRDADEETAASLRDAYAYMDVEPGQPVGGLRIDVAFLGSCTNGRVSDFLQVAEA
LERTGLRVAPGVRALAVPGSNAVREELVSRGVDAILERAGFEFRFSGCSMCLAMNPDKLV
GRELCASSSNRNFKGRQGSPTGRTMIMSPLAVAAAAVRGGIADPRSVFGTPAAPAVPVVP
AVPASRPAPAE
NT seq 1476 nt   +upstreamnt  +downstreamnt
atggcaaagacgctctacgacaaggtcttcgacctgcatgcggtacgggagctgggcgac
ggccagtaccagctcttcgtcggcctgcatctcgtccacgaggcgaccagcccgcaggcc
ttctccatgctgcgcgaacgcgggctgaaggtcgcctacccggaacgcaacatcgccacc
gccgaccacgtcatcccgaccgacaccgtgctgcgcccgtacaccgacgaactcggcgag
gcgatgctctccgaactggagcgcaacaccggcgccttcggtctgcggttcctctcgccc
gaccgcggcgagcacggcatcgtccatgtcgtcggtcccgaacggggcctgacccagccc
ggcatgaccatcgtctgcggcgactcgcacaccaccacacacggggcgttcggcgccgtg
gccctggggatcggcacctcccaggtgcgggacgtgctggccacccagaccgtggtggtg
aaccgtctgaaggtccgccgggtgcagatcgacggcgcgctcggggcgggcgtggccgcc
aaggacgtgatcctctacgtgatccaccggctcggggtgatgggcggtgtgggatacgcc
tacgagttcgcgggcgaggtggtcgaccgcatgtccatggacgagcggatgacgctgtgc
aacatggccgtggagggcggcgcgcgctgcggctacgtcaaccctgacgagaccactttc
gccgcgctccgggggcgcccgaacgcccccgccggcgcggactgggaccgggcggtggcc
tggtggcgctccgtcgcctccgacccggacgccccgtacgacgacgtggtgcgcctcgac
ggcgccgcgatcccgccgatggtgacctggggaatcaaccccggccaggccgtgccggtg
gacggcgcggtgccctcggaccgggatgccgacgaggagacggccgcctcgctgcgcgac
gcctacgcctacatggacgtcgagcccggccagccggtcggcgggctgcggatcgacgtg
gcgttcctcgggtcgtgcaccaacgggcgggtctccgacttcctccaggtggccgaggcg
ctggagcgcaccgggctgcgggtcgccccgggcgtgcgggccctcgccgtccccgggtcc
aacgcggtgcgtgaggaactcgtcagccggggtgtggacgcgatcctggagcgggccggc
ttcgagttcaggttctccgggtgctcgatgtgtctggcgatgaacccggacaagctggtc
ggccgcgagctgtgcgcgtcctcctccaaccggaacttcaaggggcgccaggggtcgccc
accggccggacgatgatcatgtctccgctcgcggtcgccgcggcggccgtgcgcggtggc
atcgccgacccgcgctccgtcttcgggacgcccgccgcacccgccgtcccggtcgtaccc
gccgtaccggcttcgcggccggcaccggccgaatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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