ID EFTU_AZOC5 Reviewed; 397 AA.
AC A8HTW6;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 16-JAN-2019, entry version 74.
DE RecName: Full=Elongation factor Tu {ECO:0000255|HAMAP-Rule:MF_00118};
DE Short=EF-Tu {ECO:0000255|HAMAP-Rule:MF_00118};
GN Name=tuf1 {ECO:0000255|HAMAP-Rule:MF_00118};
GN OrderedLocusNames=AZC_0880;
GN and
GN Name=tuf2 {ECO:0000255|HAMAP-Rule:MF_00118};
GN OrderedLocusNames=AZC_2556;
OS Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 /
OS NBRC 14845 / NCIMB 13405 / ORS 571).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC Xanthobacteraceae; Azorhizobium.
OX NCBI_TaxID=438753;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 /
RC ORS 571;
RA Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T.,
RA Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B.,
RA Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M.,
RA Oyaizu H.;
RT "Complete genome sequence of the nitrogen-fixing bacterium
RT Azorhizobium caulinodans ORS571.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC aminoacyl-tRNA to the A-site of ribosomes during protein
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00118}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_00118}.
DR EMBL; AP009384; BAF86878.1; -; Genomic_DNA.
DR EMBL; AP009384; BAF88554.1; -; Genomic_DNA.
DR RefSeq; WP_012169411.1; NC_009937.1.
DR ProteinModelPortal; A8HTW6; -.
DR SMR; A8HTW6; -.
DR STRING; 438753.AZC_2556; -.
DR PRIDE; A8HTW6; -.
DR EnsemblBacteria; BAF86878; BAF86878; AZC_0880.
DR EnsemblBacteria; BAF88554; BAF88554; AZC_2556.
DR KEGG; azc:AZC_0880; -.
DR KEGG; azc:AZC_2556; -.
DR eggNOG; ENOG4105CGV; Bacteria.
DR eggNOG; COG0050; LUCA.
DR HOGENOM; HOG000229290; -.
DR KO; K02358; -.
DR OMA; YGHIDCP; -.
DR OrthoDB; 621774at2; -.
DR BioCyc; ACAU438753:G1G2W-2674-MONOMER; -.
DR BioCyc; ACAU438753:G1G2W-910-MONOMER; -.
DR Proteomes; UP000000270; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd03697; EFTU_II; 1.
DR HAMAP; MF_00118_B; EF_Tu_B; 1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR033720; EFTU_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; TF_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50447; SSF50447; 1.
DR SUPFAM; SSF50465; SSF50465; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00485; EF-Tu; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; Elongation factor; GTP-binding;
KW Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT CHAIN 1 397 Elongation factor Tu.
FT /FTId=PRO_0000337319.
FT DOMAIN 10 207 tr-type G.
FT NP_BIND 19 26 GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT NP_BIND 82 86 GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT NP_BIND 137 140 GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT REGION 19 26 G1. {ECO:0000250}.
FT REGION 61 65 G2. {ECO:0000250}.
FT REGION 82 85 G3. {ECO:0000250}.
FT REGION 137 140 G4. {ECO:0000250}.
FT REGION 175 177 G5. {ECO:0000250}.
SQ SEQUENCE 397 AA; 43315 MW; 9F0C45938DBE8469 CRC64;
MAKAKFERNK PHCNIGTIGH VDHGKTSLTA AITKVLAETS GGATFTAYDQ IDKAPEEKAR
GITISTAHVE YETQNRHYAH VDCPGHADYV KNMITGAAQM DGAILVVSAA DGPMPQTREH
ILLARQVGVP ALVVFLNKCD MVDDPELLEL VELEVRELLS KYDFPGDDIP IVRGSALCAL
ENKSPELGAE AILKLMAEVD KYIPQPERPV DQPFLMPIED VFSISGRGTV VTGRVERGIV
KVGDEVEIVG IRPTVKTTVT GIEMFRKLLD QGQAGDNVGV LLRGTKREDV ERGQVVCKPG
SVKPHTKFKA EAYILTKEEG GRHTPFFTNY RPQFYFRTTD VTGVVTLPEG TEMVMPGDNI
SVDVQLIVPI AMEEKLRFAI REGGRTVGAG VVASIIE
//
