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Database: UniProt/SWISS-PROT
Entry: EFTU_DINSH
LinkDB: EFTU_DINSH
Original site: EFTU_DINSH 
ID   EFTU_DINSH              Reviewed;         391 AA.
AC   A8LLG2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   22-NOV-2017, entry version 69.
DE   RecName: Full=Elongation factor Tu {ECO:0000255|HAMAP-Rule:MF_00118};
DE            Short=EF-Tu {ECO:0000255|HAMAP-Rule:MF_00118};
GN   Name=tuf1 {ECO:0000255|HAMAP-Rule:MF_00118};
GN   OrderedLocusNames=Dshi_0223;
GN   and
GN   Name=tuf2 {ECO:0000255|HAMAP-Rule:MF_00118};
GN   OrderedLocusNames=Dshi_0274;
OS   Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Dinoroseobacter.
OX   NCBI_TaxID=398580;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16493 / NCIMB 14021 / DFL 12;
RX   PubMed=19741735; DOI=10.1038/ismej.2009.94;
RA   Wagner-Dobler I., Ballhausen B., Berger M., Brinkhoff T., Buchholz I.,
RA   Bunk B., Cypionka H., Daniel R., Drepper T., Gerdts G., Hahnke S.,
RA   Han C., Jahn D., Kalhoefer D., Kiss H., Klenk H.P., Kyrpides N.,
RA   Liebl W., Liesegang H., Meincke L., Pati A., Petersen J.,
RA   Piekarski T., Pommerenke C., Pradella S., Pukall R., Rabus R.,
RA   Stackebrandt E., Thole S., Thompson L., Tielen P., Tomasch J.,
RA   von Jan M., Wanphrut N., Wichels A., Zech H., Simon M.;
RT   "The complete genome sequence of the algal symbiont Dinoroseobacter
RT   shibae: a hitchhiker's guide to life in the sea.";
RL   ISME J. 4:61-77(2010).
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00118}.
DR   EMBL; CP000830; ABV91972.1; -; Genomic_DNA.
DR   EMBL; CP000830; ABV92023.1; -; Genomic_DNA.
DR   RefSeq; WP_012176905.1; NC_009952.1.
DR   ProteinModelPortal; A8LLG2; -.
DR   SMR; A8LLG2; -.
DR   STRING; 398580.Dshi_0274; -.
DR   PRIDE; A8LLG2; -.
DR   EnsemblBacteria; ABV91972; ABV91972; Dshi_0223.
DR   EnsemblBacteria; ABV92023; ABV92023; Dshi_0274.
DR   KEGG; dsh:Dshi_0223; -.
DR   KEGG; dsh:Dshi_0274; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   HOGENOM; HOG000229290; -.
DR   KO; K02358; -.
DR   OMA; YGHIDCP; -.
DR   OrthoDB; POG091H00LA; -.
DR   Proteomes; UP000006833; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Elongation factor; GTP-binding;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN         1    391       Elongation factor Tu.
FT                                /FTId=PRO_0000337373.
FT   DOMAIN       10    201       tr-type G.
FT   NP_BIND      19     26       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   NP_BIND      76     80       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   NP_BIND     131    134       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   REGION       19     26       G1. {ECO:0000250}.
FT   REGION       55     59       G2. {ECO:0000250}.
FT   REGION       76     79       G3. {ECO:0000250}.
FT   REGION      131    134       G4. {ECO:0000250}.
FT   REGION      169    171       G5. {ECO:0000250}.
SQ   SEQUENCE   391 AA;  42777 MW;  B701ECE5949571A1 CRC64;
     MAKEKFERSK PHVNIGTIGH VDHGKTTLTA AITKQFGDFK AYDEIDGAPE EKARGITIST
     AHVEYETDAR HYAHVDCPGH ADYVKNMITG AAQMDGAILV VNAADGPMPQ TREHILLGRQ
     VGIPYMVVFM NKVDQVDDEE LLELVEMEIR ELLSSYEYPG DDIPIIAGSA LAALEGRDPE
     IGEQKIAELM KAVDDYIPTP ARAVDQPFLM PIEDVFSISG RGTVVTGRVE RGVINVGDEI
     EIVGIRDTKK TTCTGVEMFR KLLDRGEAGD NIGALLRGVD REGVERGQVL CKPGSVTPHT
     KFEAEAYILT KEEGGRHTPF FANYRPQFYF RTTDVTGTVT LPEGTEMVMP GDNLKFGVEL
     IAPIAMEDGL RFAIREGGRT VGAGVVSKII E
//
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