GenomeNet

Database: UniProt/SWISS-PROT
Entry: EFTU_SYNAS
LinkDB: EFTU_SYNAS
Original site: EFTU_SYNAS 
ID   EFTU_SYNAS              Reviewed;         397 AA.
AC   Q2LQA3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2006, sequence version 1.
DT   28-FEB-2018, entry version 85.
DE   RecName: Full=Elongation factor Tu {ECO:0000255|HAMAP-Rule:MF_00118};
DE            Short=EF-Tu {ECO:0000255|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000255|HAMAP-Rule:MF_00118};
GN   OrderedLocusNames=SYNAS_02990; ORFNames=SYN_00983;
OS   Syntrophus aciditrophicus (strain SB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophaceae; Syntrophus.
OX   NCBI_TaxID=56780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB;
RA   Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A.,
RA   Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.;
RT   "The genome of the syntrophic bacterium Syntrophus aciditrophicus:
RT   Life dependent on negative change in electrical potential.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00118}.
DR   EMBL; CP000252; ABC76178.1; -; Genomic_DNA.
DR   RefSeq; WP_011416212.1; NC_007759.1.
DR   ProteinModelPortal; Q2LQA3; -.
DR   SMR; Q2LQA3; -.
DR   STRING; 56780.SYN_00983; -.
DR   PRIDE; Q2LQA3; -.
DR   EnsemblBacteria; ABC76178; ABC76178; SYN_00983.
DR   KEGG; sat:SYN_00983; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   HOGENOM; HOG000229290; -.
DR   KO; K02358; -.
DR   OMA; YGHIDCP; -.
DR   OrthoDB; POG091H00LA; -.
DR   BioCyc; SACI56780:G1G5X-292-MONOMER; -.
DR   Proteomes; UP000001933; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Elongation factor; GTP-binding;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN         1    397       Elongation factor Tu.
FT                                /FTId=PRO_1000015766.
FT   DOMAIN       10    207       tr-type G.
FT   NP_BIND      19     26       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000255|HAMAP-Rule:MF_00118}.
FT   REGION       19     26       G1. {ECO:0000250}.
FT   REGION       60     64       G2. {ECO:0000250}.
FT   REGION       81     84       G3. {ECO:0000250}.
FT   REGION      136    139       G4. {ECO:0000250}.
FT   REGION      174    176       G5. {ECO:0000250}.
SQ   SEQUENCE   397 AA;  43912 MW;  19856D475A5AE9F2 CRC64;
     MAKKKFERTK PHLNIGTIGH VDHGKTTLTA AITKWLAKKG LAEFRAFDSI DNAPEEKERG
     VTINISHVEY QTDKRHYAHV DCPGHADYIK NMISGAAHMD GTILVVAASD GPMPQTREHI
     LLARQVQVPS IVVFLNKVDL VDDPELLDLV ELELRELLNE YEFPGDDIPI IRGSALKALE
     SENPDDPDVK QIYALMDAVD AYIPEPERDL DKPFLMPVGD VFTISGRGTV VTGRIDRGII
     KTGDEVEIVG VRPTQKTVCT GVEMFRKTLD EGRAGDDVGL LLRGIKREDV ERGQVVAKPG
     SITPHTKFMA QVYVLTKEEG GRHTPFFTGY RPQFYFRTTD VTGVAKLAEG VEMVMPGDNV
     EMEVTLITPI AMEEQLRFAI REGGRTVGAG VVSKVIE
//
DBGET integrated database retrieval system