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Database: UniProt/SWISS-PROT
Entry: HSLO_BACVZ
LinkDB: HSLO_BACVZ
Original site: HSLO_BACVZ 
ID   HSLO_BACVZ              Reviewed;         291 AA.
AC   A7Z0J4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   08-MAY-2019, entry version 77.
DE   RecName: Full=33 kDa chaperonin {ECO:0000255|HAMAP-Rule:MF_00117};
DE   AltName: Full=Heat shock protein 33 homolog {ECO:0000255|HAMAP-Rule:MF_00117};
DE            Short=HSP33 {ECO:0000255|HAMAP-Rule:MF_00117};
GN   Name=hslO {ECO:0000255|HAMAP-Rule:MF_00117};
GN   OrderedLocusNames=RBAM_000820;
OS   Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus
OS   amyloliquefaciens subsp. plantarum).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus amyloliquefaciens group.
OX   NCBI_TaxID=326423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23117 / BGSC 10A6 / FZB42;
RX   PubMed=17704766; DOI=10.1038/nbt1325;
RA   Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K.,
RA   Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H.,
RA   Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H.,
RA   Strittmatter A., Gottschalk G., Borriss R.;
RT   "Comparative analysis of the complete genome sequence of the plant
RT   growth-promoting bacterium Bacillus amyloliquefaciens FZB42.";
RL   Nat. Biotechnol. 25:1007-1014(2007).
CC   -!- FUNCTION: Redox regulated molecular chaperone. Protects both
CC       thermally unfolding and oxidatively damaged proteins from
CC       irreversible aggregation. Plays an important role in the bacterial
CC       defense system toward oxidative stress. {ECO:0000255|HAMAP-
CC       Rule:MF_00117}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00117}.
CC   -!- PTM: Under oxidizing conditions two disulfide bonds are formed
CC       involving the reactive cysteines. Under reducing conditions zinc
CC       is bound to the reactive cysteines and the protein is inactive.
CC       {ECO:0000255|HAMAP-Rule:MF_00117}.
CC   -!- SIMILARITY: Belongs to the HSP33 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00117}.
DR   EMBL; CP000560; ABS72520.1; -; Genomic_DNA.
DR   RefSeq; WP_004264606.1; NC_009725.1.
DR   SMR; A7Z0J4; -.
DR   EnsemblBacteria; ABS72520; ABS72520; RBAM_000820.
DR   KEGG; bay:RBAM_000820; -.
DR   eggNOG; ENOG4105F4C; Bacteria.
DR   eggNOG; COG1281; LUCA.
DR   HOGENOM; HOG000261703; -.
DR   KO; K04083; -.
DR   OMA; DMQCECC; -.
DR   BioCyc; BAMY326423:G1G84-82-MONOMER; -.
DR   Proteomes; UP000001120; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd00498; Hsp33; 1.
DR   Gene3D; 3.55.30.10; -; 1.
DR   Gene3D; 3.90.1280.10; -; 1.
DR   HAMAP; MF_00117; HslO; 1.
DR   InterPro; IPR000397; Heat_shock_Hsp33.
DR   InterPro; IPR016154; Heat_shock_Hsp33_C.
DR   InterPro; IPR016153; Heat_shock_Hsp33_N.
DR   PANTHER; PTHR30111; PTHR30111; 1.
DR   Pfam; PF01430; HSP33; 1.
DR   PIRSF; PIRSF005261; Heat_shock_Hsp33; 1.
DR   SUPFAM; SSF118352; SSF118352; 1.
DR   SUPFAM; SSF64397; SSF64397; 1.
PE   3: Inferred from homology;
KW   Chaperone; Complete proteome; Cytoplasm; Disulfide bond;
KW   Redox-active center; Zinc.
FT   CHAIN         1    291       33 kDa chaperonin.
FT                                /FTId=PRO_1000015531.
FT   DISULFID    235    237       Redox-active. {ECO:0000255|HAMAP-
FT                                Rule:MF_00117}.
FT   DISULFID    268    271       Redox-active. {ECO:0000255|HAMAP-
FT                                Rule:MF_00117}.
SQ   SEQUENCE   291 AA;  31856 MW;  78DE96ED4D1E0F2B CRC64;
     MDYLIKAIAY DGKVRAYAAR TTDMVNEAQR RHDTWPTASA AIGRTMTASL MLGAMLKGED
     KLTVKIEGGG PIGAIVADAN AKGEVRAYVS NPHVHFDLNE QGKLDVRRAV GTDGTLSVVK
     DLGLRDYFTG QVEIVSGELG DDFTYYLVSS EQVPSSVGVG VLVNPDNTIL AAGGFIIQLL
     PGTDEETIST IEKQLSQIEP ISKLIQKGLT PEEILEEVLG QKPDVLETMP VKFHCSCSKD
     RFETAILGLG KKEIQDMIEE DGKAEAVCHF CNEKYLFTKE ELEELRDETT R
//
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