GenomeNet

Database: UniProt/SWISS-PROT
Entry: PORA_METJA
LinkDB: PORA_METJA
Original site: PORA_METJA 
ID   PORA_METJA              Reviewed;         389 AA.
AC   Q57715;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   05-DEC-2018, entry version 100.
DE   RecName: Full=Pyruvate synthase subunit PorA;
DE            EC=1.2.7.1;
DE   AltName: Full=Pyruvate oxidoreductase alpha chain;
DE            Short=POR;
DE   AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit alpha;
GN   Name=porA; OrderedLocusNames=MJ0267;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 /
OS   JCM 10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci;
OC   Methanococcales; Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D.,
RA   Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D.,
RA   Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I.,
RA   Overbeek R., Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A.,
RA   Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D.,
RA   Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C.,
RA   Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M.,
RA   Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate =
CC         acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:12765, Rhea:RHEA-COMP:10000, Rhea:RHEA-
CC         COMP:10001, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one
CC       gamma chain. {ECO:0000250}.
DR   EMBL; L77117; AAB98254.1; -; Genomic_DNA.
DR   PIR; D64333; D64333.
DR   ProteinModelPortal; Q57715; -.
DR   SMR; Q57715; -.
DR   STRING; 243232.MJ_0267; -.
DR   EnsemblBacteria; AAB98254; AAB98254; MJ_0267.
DR   KEGG; mja:MJ_0267; -.
DR   eggNOG; arCOG01608; Archaea.
DR   eggNOG; COG0674; LUCA.
DR   InParanoid; Q57715; -.
DR   KO; K00169; -.
DR   OMA; WNDQQDS; -.
DR   OrthoDB; POG093Z02MK; -.
DR   PhylomeDB; Q57715; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   Gene3D; 3.40.50.920; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; SSF52518; 1.
DR   SUPFAM; SSF52922; SSF52922; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase; Reference proteome.
FT   CHAIN         1    389       Pyruvate synthase subunit PorA.
FT                                /FTId=PRO_0000099896.
SQ   SEQUENCE   389 AA;  42971 MW;  2CAA3DDE3EB0F5A9 CRC64;
     METMCEVKVI TGTSAAAEAA KLADVDVIAA YPITPQTTCV EKLAEFVANG ELDAEYIKVE
     SEHSAMSACI GAAATGARTF TATASQGLAL MHEMLFIASG MRLPIVMMVA NRALSAPINI
     WNDHQDSIAE RDSGWIQIYV EDNQETLDSI IQAYKIAENE DVLLPVMVCL DGFILTHTVE
     PVTIPKAERV REFLGVYEPK HAYLDPDRPI TQGPVGVPDC YMETRKQIEE AMERAKKVIR
     DVNEEFAEWF KRKYGNGLVE AYNLDNADTV LVAMGSVCGT IKYVIDELKK EGKNVGLLRI
     RAFRPFPKED VKELLKDANN IAVLDKNISL GFNKGALGIE MASILKNKKV CNYIVGLGGR
     DIKIDDIKTI INHVEKAEDD STLWVGLKE
//
DBGET integrated database retrieval system