KEGG   Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0656
Entry
MGAS9429_Spy0656  CDS       T00358                                 
Symbol
rmlD
Name
(GenBank) dTDP-4-dehydrorhamnose reductase
  KO
K00067  dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
Organism
spk  Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00521  Streptomycin biosynthesis
spk00523  Polyketide sugar unit biosynthesis
spk00541  O-Antigen nucleotide sugar biosynthesis
spk01100  Metabolic pathways
spk01110  Biosynthesis of secondary metabolites
spk01250  Biosynthesis of nucleotide sugars
Module
spk_M00793  dTDP-L-rhamnose biosynthesis
Brite
KEGG Orthology (KO) [BR:spk00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    MGAS9429_Spy0656 (rmlD)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    MGAS9429_Spy0656 (rmlD)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    MGAS9429_Spy0656 (rmlD)
Enzymes [BR:spk01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.133  dTDP-4-dehydrorhamnose reductase
     MGAS9429_Spy0656 (rmlD)
SSDB
Motif
Pfam: RmlD_sub_bind Epimerase GDP_Man_Dehyd Polysacc_synt_2 3Beta_HSD NAD_binding_4 KR
Other DBs
NCBI-ProteinID: ABF31844
UniProt: Q1JMG8
Position
642368..643282
AA seq 304 aa
MLENTKILRKVFYLWQKGELMILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNED
KVEAVFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYIS
TDYVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDTTW
YDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKAFYQQ
GLKK
NT seq 915 nt   +upstreamnt  +downstreamnt
atgttagagaacactaagatactgagaaaagtgttctacctatggcaaaaaggagaactg
atgattttaattacaggaagcaatggtcaattagggacagaacttcgatacttattagat
gaacgaggtgttgattatgtagccgttgatgtcgcagaaatggacatcacaaatgaagac
aaagtcgaagctgtttttgcgcaggtcaagccaacattggtctatcattgtgctgcttat
acggcagttgatgcagcagaagacgaaggaaaagccttgaatgaggctattaatgtaaca
ggctcagaaaatattgccaaggcttgtggaaaatatggggctacccttgtttacatttca
acagactacgtatttgatggcaataaaccagtcggtcaagaatgggtagaaacagatcgt
ccagaccctaagacagaatatggccgtacaaaacgtttaggagaactagctgttgaacga
tacgcagagcatttttatattatccgtactgcttgggtatttggaaattatggtaaaaac
tttgtctttaccatggagcagttagcggaaaatcactcccgtttgactgttgtcaatgac
caacacggtcggccaacgtggacaagaaccttggcagaattcatgtgttatttgacagag
aatcaaaaagcctttggttactatcacttgtcaaatgatgctaaggaagacaccacttgg
tatgattttgccaaagaaatcttaaaagacaaggctgttgaagtggtgccagttgattca
tcagctttcccagcaaaagccaaacgtcctttaaattcaaccatgaatcttgataaggca
aaagcaacagggtttgttattccaacatggcaagaagccttgaaggcattttaccaacaa
ggactgaaaaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (28)   

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