KEGG   Streptococcus pyogenes MGAS8232 (serotype M18): spyM18_2244
Entry
spyM18_2244       CDS       T00079                                 
Symbol
impd
Name
(GenBank) inosine monophosphate dehydrogenase
  KO
K00088  IMP dehydrogenase [EC:1.1.1.205]
Organism
spm  Streptococcus pyogenes MGAS8232 (serotype M18)
Pathway
spm00230  Purine metabolism
spm01100  Metabolic pathways
spm01110  Biosynthesis of secondary metabolites
spm01232  Nucleotide metabolism
Module
spm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:spm00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    spyM18_2244 (impd)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:spm04147]
    spyM18_2244 (impd)
Enzymes [BR:spm01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.205  IMP dehydrogenase
     spyM18_2244 (impd)
Exosome [BR:spm04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   spyM18_2244 (impd)
  Exosomal proteins of breast cancer cells
   spyM18_2244 (impd)
SSDB
Motif
Pfam: IMPDH CBS NMO FMN_dh PEP_mutase His_biosynth QRPTase_C Glu_synthase
Other DBs
NCBI-ProteinID: AAL98673
UniProt: P68839
Position
complement(1881737..1883218)
AA seq 493 aa
MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSK
MAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRY
RISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMTSEHLVTAAVGTDLETAERIL
HEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAE
ALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVV
KVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGG
NAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVP
EGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHENAQFVEMSGAGLIESHPHD
VQITNEAPNYSVH
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgtcaaattgggacactaaatttttaaaaaaaggctacacttttgacgatgtcttgctt
attccggcagagagtcatgttcttccaaatgaagttgatttaaagacaaaactcgcagac
aatttgacattaaatattcctattattacagcagctatggatacggttactggtagtaaa
atggctattgcaattgcgcgtgcgggtggtttaggtgttattcataaaaacatgtctatt
actgagcaagcagaagaagttcgcaaggtaaaacgttctgaaaatggtgtcatcattgat
ccattcttcttaacacctgaacacaaggtttcagaagctgaagaattaatgcagcgctac
cgtatcagtggtgtgccaattgttgaaactttagcaaaccgtaagttggtcggtatcatt
actaatcgtgatatgcgttttatttctgattacaatgcaccaatctctgaacatatgact
agtgagcacctcgttacggctgctgttggtacagatcttgaaactgcagaacgtattctt
catgaacaccgtattgaaaaacttcctttggttgataatagcggtcgtctatctggttta
atcactatcaaagatattgaaaaagtaatcgaattcccacatgctgctaaagatgaattt
ggtcgtcttctggtcgctgctgcggtaggtgttacctcagatacttttgagcgtgccgag
gccttgtttgaagctggtgcagatgcgattgttattgacacagctcatggtcattcggct
ggtgttcttcgtaaaattgctgagattcgtgctcatttcccaaatcgtactttgattgct
ggaaatattgccactgctgaaggtgcgcgtgctctttatgatgcaggtgttgatgttgtt
aaagtgggtattggtcccggatctatctgtaccactcgtgtggttgcaggtgtcggtgtt
cctcaagtgactgctatttacgatgctgctgctgttgctcgtgaatatggcaaaacgatt
attgctgatggtggtatcaagtattctggcgatattgttaaggctcttgcagccggtggt
aatgctgttatgcttggatcaatgtttgcaggtactgatgaagctccaggtgaaactgaa
atctaccaaggccgtaagttcaaaacttatcgtggaatgggttccattgcagctatgaag
aaaggatcaagcgatcgttacttccaaggttccgtcaatgaagctaataaactagttcca
gaaggtattgaaggccgtgttgcttataaaggagctgcttcagatattgtcttccaaatg
ttaggtggtatccgctcaggtatgggctatgttggcgcaggtgacattcaagaattacat
gaaaatgctcaatttgttgaaatgtcaggtgcaggcttgattgaaagtcatccacatgat
gttcaaatcacaaatgaagcaccaaactattctgtgcactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (8)   
   Pfam (8)   
All databases (33)   

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