KEGG   Schizosaccharomyces pombe (fission yeast): SPCC1223.08c
Entry
SPCC1223.08c      CDS       T00076                                 
Symbol
dfr1
Name
(RefSeq) dihydrofolate reductase Dfr1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
spo  Schizosaccharomyces pombe (fission yeast)
Pathway
spo00670  One carbon pool by folate
spo00790  Folate biosynthesis
spo01100  Metabolic pathways
spo01240  Biosynthesis of cofactors
Module
spo_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:spo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SPCC1223.08c (dfr1)
   00670 One carbon pool by folate
    SPCC1223.08c (dfr1)
Enzymes [BR:spo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SPCC1223.08c (dfr1)
SSDB
Motif
Pfam: FSH1 DHFR_1 Hydrolase_4 Abhydrolase_2
Other DBs
NCBI-GeneID: 2539048
NCBI-ProteinID: NP_588353
PomBase: SPCC1223.08c
Ensembl: SPCC1223.08c
UniProt: P36591
Position
III:1855307..1857115
AA seq 461 aa
MSKPLKVLCLHGWIQSGPVFSKKMGSVQKYLSKYAELHFPTGPVVADEEADPNDEEEKKR
LAALGGEQNGGKFGWFEVEDFKNTYGSWDESLECINQYMQEKGPFDGLIGFSQGAGIGAM
LAQMLQPGQPPNPYVQHPPFKFVVFVGGFRAEKPEFDHFYNPKLTTPSLHIAGTSDTLVP
LARSKQLVERCENAHVLLHPGQHIVPQQAVYKTGIRDFMFSAPTKEPTKHPRDLTMIVAV
SSPNLGIGKKNSMPWHIKQEMAYFANVTSSTESSGQLEEGKSKIMNVVIMGRSCYDSLPK
KNRPLKDRINIVITRNSNYNFGLTKKEKMPENLYAADCIDSALDLVAEKYGADSDIQVGK
VFIIGGSFLYGSALYHPLTKNLLFTRIHKEYPCDSFFPFEPAESSDWVRKAHPELEKFVG
IPVEEGRLKAASSNKEEVEIEFELYGKNDDVNVALEKLSIC
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtctaagcctttaaaagtgctgtgtcttcatggatggattcaatctggtcccgtattt
tcaaaaaaaatgggatccgtccagaaatacctgtctaagtatgccgaattgcattttcca
acaggtcctgtggtcgctgacgaagaagcagaccccaatgatgaagaagagaagaaacgc
cttgctgcgcttggtggtgaacaaaacggtggtaaatttgggtggtttgaagtggaggat
tttaaaaatacatacggaagttgggatgaaagtcttgaatgtataaatcaatacatgcaa
gaaaaaggtccctttgatggacttatcggattttctcaaggtgcaggaataggtgctatg
ctggctcaaatgcttcagcctggtcaacctcccaacccttatgtccaacatcctcctttt
aaatttgttgtttttgttggcggtttccgtgctgaaaagcctgaattcgatcatttttat
aaccccaagcttaccactccttcgttacatattgctggtacttctgataccctggtccca
cttgctcgctccaaacagttggttgaacgttgcgaaaatgcacacgttttgttgcatccg
ggacaacatattgttcctcaacaagcagtgtataagactggcatccgtgatttcatgttt
tccgcccctaccaaggaacccactaagcaccctcgtgatcttacaatgattgtcgcggtt
tcttcgccaaacctcggtatcggaaagaagaactccatgccttggcatattaaacaagaa
atggcttactttgccaatgttacatcttctaccgaaagtagcggccaactggaagaagga
aaatccaagattatgaacgttgtaatcatgggtcgtagttgctacgacagtttgcccaag
aagaaccgtcctttgaaggatcgtatcaacattgttattacacgcaattctaactacaac
tttggtttgaccaaaaaagaaaagatgcccgagaatctgtatgcggctgattgtattgac
tcagcattggacctcgtggctgagaagtatggagctgatagcgacatccaagttggaaaa
gtgtttatcattggtggctctttcctttatggaagtgctctttaccatcctttgaccaaa
aaccttcttttcactcgtatccacaaagaatatccttgtgattctttctttccctttgaa
ccagctgaatcatctgactgggttagaaaggctcatcctgaattggaaaagtttgttggt
attccggtagaggaaggtcgtctgaaggcagcttcctcaaacaaagaagaggttgaaata
gaattcgagctttatggaaagaacgatgatgttaatgtagctttagaaaagcttagtatt
tgttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   POMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (62)   

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