KEGG   Strongylocentrotus purpuratus (purple sea urchin): 754280Help
Entry
754280            CDS       T01019                                 

Definition
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
spu  Strongylocentrotus purpuratus (purple sea urchin)
Pathway
spu00562  Inositol phosphate metabolism
spu04068  FoxO signaling pathway
spu04070  Phosphatidylinositol signaling system
spu04140  Autophagy - animal
spu04150  mTOR signaling pathway
spu04933  AGE-RAGE signaling pathway in diabetic complications
Module
spu_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:spu00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    754280
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    754280
   04070 Phosphatidylinositol signaling system
    754280
   04150 mTOR signaling pathway
    754280
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    754280
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    754280
  Infectious diseases
   05163 Human cytomegalovirus infection
    754280
Enzymes [BR:spu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     754280
Membrane trafficking [BR:spu04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    754280
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3Ka PI3K_C2 C2
Motif
Other DBs
NCBI-GeneID: 754280
NCBI-ProteinID: XP_011680857
Position
Un
AA seq 503 aa AA seqDB search
MLMSKDTVLNSLPDVHLLLPSYMRRASTMPSDRTTSCVWEVEENLRVKINFATYVNVKEL
DKIYVRTGIYHGEEPLCPIVSTEQVPWSNPRWNEWLTYDIKVNDIPRSARWCVSICSSEK
RKGKKEGGFAIPWGNINLFDFTTRLQMANMRLYLWPPPKGNDDLLNPFGQTGPNPNKDAP
CLELEFYRYPHSLLFPCYSQIQQFAFFVTKAQRREEINGEKPPTEEELVLLEEILNRDRL
HEMSVQEKELVWKLRLVCREYPYSLPKLLSSVKWYSREDVSQLYVLLKDWPDMDAETALG
LLDCSYADLGVRTEAVNCLDRMSDEQVTQYLLQLVQVLKYESYLDNPLARFLLKRSLYNQ
RIGHFFFWHLRSEMHKPSVSRRFGLMLEAYCRSLGPYLKLLVRQVEALDKLSKLTEMLNE
KKDDTNRDRLKYLAEHMAQPDFIEALQELPLPLNPSFSLGKLRVDKCKIMSSAKRPLWLE
WENPDQMSMSMCEDLKIIFKRGD
NT seq 1510 nt NT seq  +upstreamnt  +downstreamnt
atgctgatgtccaaagacaccgtcctcaacagtctcccggacgtccacctcctactaccg
tcctacatgagacgggcttccaccatgccttccgaccggaccacctcctgcgtctgggag
gtagaggagaacctgagagtcaagatcaactttgccacctacgtcaacgtcaaggaacta
gacaagatatacgtccgaacaggcatctaccacggggaagagcctctgtgccccatcgtg
tctacggagcaggtcccgtggtcaaaccctcgctggaacgagtggttgacctatgacatc
aaggtcaatgacattcctcgtagcgctaggtggtgcgtctcgatatgctcatcggagaag
aggaaaggaaagaaagagggtggctttgcaataccctggggcaacatcaacctctttgac
ttcaccacccggcttcagatggccaacatgcgcctctacctctggcccccgcccaagggc
aacgacgacctcctcaaccccttcggccagactggaccaaaccccaacaaggacgccccg
tgcctggaactggagttctaccgctaccctcacagtctgctcttcccgtgctactcccag
atccagcagtttgcctttttcgtgaccaaagcgcagaggagggaagagataaacggggag
aaacctcctacggaagaggagctcgtgctactggaggaaatcttgaacagggacagactg
catgagatgtctgtgcaggagaaagaacttgtctggaaactcagacttgtatgcagagaa
tatccatactcgctaccaaagctgcttagctctgtcaaatggtacagcagagaggatgta
tcacagctgtacgttctcttgaaggactggccagacatggacgccgagactgctctaggt
ctcctagactgtagctatgctgatctgggtgtcaggacagaagcagtcaactgcctagat
cgtatgtcggatgaacaggtcacacaatacttacttcaacttgtacaggttttgaagtac
gagtcctacctagacaaccctcttgccaggtttcttctcaaacgatctctgtacaaccaa
aggattggacacttcttcttctggcatctaagatctgagatgcacaagccgagcgtgagc
agacgttttggtctgatgcttgaagcgtactgccggtcactcggtccatacctcaagctg
ctggtcagacaggtggaggctctggacaaactctccaagcttaccgaaatgctcaatgag
aagaaggacgacacaaacagggaccggttaaaatacctagcagagcacatggcacagccg
gacttcatcgaagctctccaggagcttcccttacccctgaacccctccttctccttgggc
aagctcagagtcgacaagtgcaagatcatgtcgtctgcaaagcgccctctatggctagaa
tgggagaacccggatcagatgtcaatgtccatgtgtgaagatctcaagattatcttcaag
aggggtgatg

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