KEGG   Streptomyces rapamycinicus: M271_38475
Entry
M271_38475        CDS       T02907                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
src  Streptomyces rapamycinicus
Pathway
src00270  Cysteine and methionine metabolism
src00450  Selenocompound metabolism
src00670  One carbon pool by folate
src01100  Metabolic pathways
src01110  Biosynthesis of secondary metabolites
src01230  Biosynthesis of amino acids
src04980  Cobalamin transport and metabolism
Brite
KEGG Orthology (KO) [BR:src00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    M271_38475
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    M271_38475
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    M271_38475
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    M271_38475
Enzymes [BR:src01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     M271_38475
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AGP59087
Position
9401176..9404679
AA seq 1167 aa
MASHTPSPTSAARADALREALATRVVVADGAMGTMLQAQEPSLDDFQQLEGCNEILNITR
PDIVRSVHEAYYAVGVDCVETNTFGANHAALGEYDIPHRVHELSEAGARIAREVADEFGA
DGRQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQANAEGMIAGGADALLVETTQDLLQTKA
SIIGARRALEATGANLPVICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGPA
EMSEHLRHLARHSRIPLSCMPNAGLPVLGKDGAHYPLTPGELADAQETFVREYGLSLVGG
CCGTTPEHLRQVVERVRELTPTERTPRPEPGAASLYQTVPFRQDTSYLAIGERTNANGSK
KFREAMLEARWDDCVEIAREQIREGAHLLDLCVDYVGRDGVADMEELAGRFATASTLPIV
LDSTEVDVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTRLAQEHGAALIALTIDEEG
QARTPEKKVEIAERLIADLTGNWGIHESDILIDTLTFTICTGQEESRKDGIATIEAIREL
KRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIARFEEE
QVRTALDLVYDRRAEGYDPLQKLMGLFEGATAKSLKAGKAEELAALPLEERLKRRIIDGE
RNGLEADLDEALQERPALDIVNETLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAHL
EPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEAAE
EHRADVIGMSGLLVKSTVIMKENLEELNQRKLAARFPVILGGAALTRAYVEQDLHEIYEG
EVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVPKRDVSVNEPEPEGPSRSDVAT
DNPVPTPPFWGTRVVKGIQQADYASWLDEGALFKGQWGLKQARTGEGPSYQELVESEGRP
RLRGWLDKLHTENLLEAAVVYGYFPCVSKGDDLVLLNEDGSERTRFTFPRQRRGRRLCLA
DFFRPEESGETDVVGLQVVTVGSKIGEATGELFAADSYRDYLELHGLSVQLAEALAEYWH
ARVRSELGFSGEDPSEMEDMFALKYRGARFSLGYGACPDLEDRAKIADLLGPERIGVKLS
EEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3504 nt   +upstreamnt  +downstreamnt
atggcctctcatacgccatcgcccacatccgccgcccgagccgacgcgctccgcgaagcg
ctggccacccgcgtggtggtcgccgacggcgcgatggggacgatgctccaggcgcaggag
cccagtctcgacgacttccagcagctcgagggctgcaacgagatcctcaacatcacccgc
ccggacatcgtccgctcggtccacgaggcgtactacgccgtcggcgtggactgcgtcgag
accaacaccttcggcgccaaccacgcggcgctcggtgagtacgacatcccccaccgcgtc
cacgagctctccgaggccggcgcccggatcgcccgtgaggtcgccgacgagttcggcgcc
gacggacgccagcgctgggtgctgggctccatgggcccgggcaccaagctgcccaccctc
ggccacgccccgtacaccaccctccgcgacgcctaccaggccaacgccgaaggaatgatc
gccggcggcgcggacgccctcctggtggagaccacccaggacctgctgcagaccaaggcc
tcgatcatcggcgcccgccgcgccctcgaggccaccggtgccaacctcccggtgatctgc
tcggtcaccgtcgagaccaccggcaccatgctgctcggctccgagatcggcgcggcgctc
accgccctcgaaccgctcggcatcgacatgatcggcctcaactgcgccaccggccccgcc
gagatgagcgagcacctgcgccacctggcccgccactcccggatcccgctgtcctgcatg
cccaacgccggcctcccggtgctgggcaaggacggcgcccactaccccctcacccccggc
gagctcgccgacgcccaggagaccttcgtccgcgaatacgggctctccctggtcggcggc
tgctgcggcaccacgcccgagcatctgcgccaggtcgtcgagcgggtccgcgagctgacc
cccaccgagcgcaccccgcgccccgagcccggcgccgcctcgctctaccagaccgtgccg
ttccgccaggacacctcgtacctggccatcggcgagcgcaccaacgccaacggctccaag
aagttccgcgaggccatgctggaggcccgctgggacgactgcgtggagatcgcccgcgag
cagatccgcgagggcgcccatctgctcgacctgtgcgtggactacgtcggccgggacggc
gtcgcggacatggaggagctggccgggcggttcgccaccgcctccaccctccccatcgtc
ctggactccaccgaggtcgacgtcatccgggccgggctggagaagctcggcggacgcgcg
gtcatcaactccgtcaactacgaggacggggacggccccgagtcgcggttcgccaaggtc
acccggctggcccaggagcacggcgccgccctcatcgcgctgaccatcgacgaggagggc
caggcccgcacgccggagaagaaggtcgagatcgccgagcggctgatcgccgacctgacc
ggcaactggggcatccacgagtcggacatcctcatcgacaccctgaccttcaccatctgc
accggtcaggaggagtcccgtaaggacggcatcgccaccatcgaggcgatccgcgagctc
aagcgccgccacccggacgtccagaccacactgggcctgtccaacatctccttcggcctc
aacccggccgcccgcatcgtgctcaactccgtcttcctcgacgagtgcgtcaaggcgggc
ctggactcggcgatcgtgcacgcctccaagatcctgccgatcgcgcggttcgaggaggag
caggtccggaccgcactggacctggtctacgaccgccgcgccgagggctatgacccgctc
cagaagctgatggggctcttcgagggcgccaccgccaagtccctcaaggcgggcaaggcc
gaggaactggccgcgctgcccctggaggagcgcctcaagcgccgcatcatcgacggtgag
cgcaacggcctggaggccgacctcgacgaggccctccaggagcgccccgccctcgacatc
gtcaacgagacgctgctggaaggcatgaaggtggtcggcgagctgttcggctccggccag
atgcagctgccgttcgtcctccagtccgccgaggtcatgaagaccgcggtcgcccatctg
gagccgcacatggagaagtcggacgacgagggcaagggcaccatcgtgctcgccaccgtc
cgcggcgacgtccatgacatcggtaagaacctcgtggacatcatcctgtccaacaacggc
tacaacgtcgtcaacctgggcatcaagcagccggtctccgcgatcctggaggccgccgag
gagcaccgcgccgatgtgatcggcatgtccgggctgctggtgaagtccacggtgatcatg
aaggagaacctggaggagctcaaccagcgcaagctggccgcccggttccccgtgatcctc
ggcggcgccgcgctcacccgggcctatgtcgagcaggatctgcacgagatctacgagggc
gaggtgcgctacgcccgcgacgccttcgaggggctgcggctcatggacgccctgatcgcc
gtcaagcgcggcgtgcccggcgccaccctgccggagctcaagcagcgccgggtgcccaag
cgggacgtgtccgtgaacgagccggagccggagggcccgtcccggtccgacgtggccacc
gacaacccggtgcccaccccgccgttctggggcacccgcgtggtcaagggcatccagcag
gccgactacgcctcctggctggacgagggggcgctgttcaagggccagtgggggctcaag
caggcccgcaccggcgaggggccgagttatcaggagctggtggagtccgagggccgtccg
cggctgcgcggctggctcgacaagctgcacaccgagaacctgctggaggcggccgtcgtc
tacggctacttcccgtgcgtctccaagggcgacgacctggtcctgctgaacgaggacggc
agcgagcggacccgcttcaccttcccgcgccagcgccgcggccgccggctgtgcctggcc
gacttcttccgccccgaggagtcgggtgagacagatgtcgtcggcctccaggtggtgacc
gtcggctcgaagatcggcgaggccaccggcgagctgttcgccgccgactcctaccgcgac
tacctggagctgcacggcctgtccgtccagctggcggaggcgctggccgagtactggcac
gcccgggtccgctccgagctgggcttctccggtgaggacccgagcgagatggaggacatg
ttcgcgctgaagtaccgcggcgcgcgcttctcgctgggctacggcgcctgccccgacctg
gaggaccgcgcgaagatcgccgacctgctggggccggagcggatcggggtgaagctctcg
gaggagttccagctccaccccgagcagtccacggacgccatcgtgatccaccacccggag
gcgaagtacttcaacgcgcggtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (30)   

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