KEGG   Streptomyces reticuli: TUE45_07304
Entry
TUE45_07304       CDS       T04246                                 
Symbol
shc
Name
(GenBank) Squalene--hopene cyclase
  KO
K06045  squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:5.4.99.17 4.2.1.129]
Organism
srw  Streptomyces reticuli
Pathway
srw00909  Sesquiterpenoid and triterpenoid biosynthesis
srw01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:srw00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    TUE45_07304 (shc)
Enzymes [BR:srw01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.129  squalene---hopanol cyclase
     TUE45_07304 (shc)
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.17  squalene---hopene cyclase
     TUE45_07304 (shc)
SSDB
Motif
Pfam: SQHop_cyclase_C SQHop_cyclase_N Prenyltrans TED_complement PGM1_C
Other DBs
NCBI-ProteinID: CUW32554
Position
I:8274803..8276833
AA seq 676 aa
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVQEAAARAARRATDFLLARQDTQGWWKG
DLETNVTMDAEDLLLRQFLGILDDKTTQAAAKFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWIRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPQPLAPLAS
WDGVFQRLDKVVRGYRKVAVRRLRKAAMNSAARWIVERQENDGCWGGIQPPAVYSIIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLERVQNDDGGWGEDLRSYQDAKEWSGRGASTASQTAWALMALLAAGERGSE
AVERGIRWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
ILPAKTATAASRADGS
NT seq 2031 nt   +upstreamnt  +downstreamnt
atgacagcgacgaccgacggaagcaccggggcgaccttgccgtcccgcgctgccgcggcc
agcgacaccaccctcaccacccccgaggcggccggggtacaagaagccgccgcacgcgcc
gcacggcgcgccaccgacttcctgctcgcccggcaggacacccagggctggtggaagggc
gacctggagaccaacgtcaccatggacgccgaggatctgctgctccgccagttcctgggc
atcctggacgacaagacgacgcaggccgccgcgaagttcatccgcggcgagcagcgcgag
gacggcacctgggccaccttctacggcggacccggcgaactgtccaccaccatcgaggcg
tacgtcgccctgcggctggccggcgacgcgcccgacgccccgcacatggcgaaggcgtcc
gcctggatccgcgaacgcggcggcatcgccgcctcccgggtcttcacccggatctggctc
gccctgttcggctggtggaagtgggaggacctgcccgaactcccgccggagctgatctac
ttccccacctggttcccgctcaacatctacaacttcggatgctgggcccggcagaccatc
gtgccgctgaccatcgtctccgccaagcgcccggtgcgtcccgcccccttcgcgctggac
gagctgcacaccgacccggcccaccccaacccgccgcagccgctcgccccgctggcgagc
tgggacggcgtcttccagcggctcgacaaggtggtccgcggctaccgcaaggtcgccgtg
cgcaggctccgcaaggccgcgatgaactcggcggcccgctggatcgtcgagcgccaggag
aacgacggctgctggggcggcatccagccgccggccgtgtactcgatcatcgccctccat
ctgctcggctacgacctggagcacccggtgctgcgcgagggcctcgcctcgctcgaccgc
ttcgccgtctggcgcgaggacggcgcgcggatgatcgaggcctgccagtccccggtgtgg
gacacctgcctggccaccatcgccctcgtggacgccggtctgccggtcgaccatccgcaa
ctggtcaaggcggccgactggatgctcggcgaggagatcgtccggcccggcgactgggcc
gtgcggcggccccaactgcccccgggcggctgggcgttcgagttccacaacgacaactac
ccggacatcgacgacaccgccgaggtcgccctcgcgctgcgccgggtccggcaccacgac
ccggagcgggtggaccgggcgatcgggcgggccgtccgctggaacctcggcatgcagtcg
aagaacggcgcctggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcaccgcgcacgtc
gtggagatgctcgccgccgagggcctggcccacgacccgcgcacccggcgcggcatcgac
tggctgctcgccgaacaggaaccggacggctcgtggttcggccgctggggggtcaactac
ctctacggcaccgggtcggtcgtccccgcgctcaccgcggccgggctgcccggctcgcac
ccggcgatccggcgggccgtggcctggctggagcgcgtccagaacgacgacggcggctgg
ggcgaggacctgcgctcctaccaggacgccaaggagtggagcggccggggcgcctccacc
gcctcgcagacggcgtgggcgctgatggcgctgctcgccgcgggggagaggggctccgag
gccgtcgagcgcggcatccggtggctggccgagacccagcgggaggacggcagctgggac
gagccgtacttcaccggcaccggcttcccctgggacttctccatcaactaccacctctac
cggcaggtgttcccgctcaccgcgctcggccgctacctgcacggggaccccttcgagcgc
atcctgccggccaagaccgcgacggccgcgtcccgggccgacgggagctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (21)   

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