KEGG   Sus scrofa (pig): 100152910Help
Entry
100152910         CDS       T01009                                 

Gene name
CYP1A2
Definition
(RefSeq) cytochrome P450 1A2
  KO
K07409  cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00140  Steroid hormone biosynthesis
ssc00232  Caffeine metabolism
ssc00380  Tryptophan metabolism
ssc00591  Linoleic acid metabolism
ssc00830  Retinol metabolism
ssc00980  Metabolism of xenobiotics by cytochrome P450
ssc00982  Drug metabolism - cytochrome P450
ssc01100  Metabolic pathways
ssc05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    100152910 (CYP1A2)
   00591 Linoleic acid metabolism
    100152910 (CYP1A2)
  Amino acid metabolism
   00380 Tryptophan metabolism
    100152910 (CYP1A2)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100152910 (CYP1A2)
  Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    100152910 (CYP1A2)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100152910 (CYP1A2)
   00982 Drug metabolism - cytochrome P450
    100152910 (CYP1A2)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    100152910 (CYP1A2)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     100152910 (CYP1A2)
Cytochrome P450 [BR:ssc00199]
 Cytochrome P450, animal type
  CYP1 family
   100152910 (CYP1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: p450 FANCI_HD1
Motif
Other DBs
NCBI-GeneID: 100152910
NCBI-ProteinID: NP_001153086
Ensembl: ENSSSCG00000001901
UniProt: F1SJ26
Position
7
AA seq 516 aa AA seqDB search
MTLFQPSLFSATELLLASAIFCLVFWVVRTWQPQVPKGLKSPPGPWGWPLLGHVLTLGKS
PHLALARLSQCYGDVLQIRIGCTPVLVLSGLDTIRQALVRQGDDFKGRPNLYSFTLVTDG
QSMTFNPDSGPVWAARRRLAQKALNTFSIASDPASSSSCYLEDHVSKEAECLLGKFQELM
AGPGHFDPYDHIVVSVGRVIGAMCFGKGFPQSSEEMFSIVKNSHEFVETASSGNPVDFFP
ILRYLPSPTLQRFKSFNQRLLQFLRKMVQERYRDFDKNCIQDITSALFKHSEENSSTSGG
LISQEKTINLVNDIFGAGFDTITTAISWSLLYLVTYPEIQKKIQKELDTVIGRARRPRLS
DRPQLPYMEAFILELFRHTSFVPFTIPHSTTRDTTLNGFYIPKERHVLVNQWQVNHDPKL
WGDPSEFRPERFLTADGTAIHKTMSEKVILFGMGKRRCIGEVLAKWEVFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHAHCKHFQAHLRFPIK
NT seq 1551 nt NT seq  +upstreamnt  +downstreamnt
atgacattattccagcccagtctcttctcagccacagagctgctcctggcctctgccatc
ttctgccttgtattctgggtggtcaggacctggcagcctcaggtccccaaaggcctgaag
agtccaccagggccctggggctggcccctgctcgggcacgtgctgaccttgggcaagagc
ccacacctggccctggcaaggctgagccagtgctatggagatgtgctgcaaatccgcatt
ggctgcacccctgtgctggtgctcagcggcctggacaccatccggcaggccctggtgcgg
cagggcgacgatttcaagggacggcccaacctctacagcttcactctggtcactgatggc
cagagcatgaccttcaacccagactctggaccagtgtgggctgcccgtcggcgcctggcc
cagaaggctcttaacaccttctccattgcctcagacccggcttcctcctcctcctgctac
ctggaggatcatgtgagcaaggaggctgagtgcctccttggcaagttccaggagctgatg
gcagggcctgggcactttgatccctatgaccacattgtggtgtcagtgggccgtgtcatc
ggtgccatgtgcttcgggaagggcttcccacagagcagtgaggagatgttcagcatcgtg
aagaacagtcatgaatttgtggagaccgcctcatccgggaaccccgtggacttcttcccc
atccttagatatctgcccagccctactctgcaaagattcaagagtttcaatcaaaggctc
ctgcaattcctgaggaaaatggtccaggagcgctatcgggactttgacaagaactgtatc
caggacatcacaagcgccctattcaagcacagcgaggagaattccagcaccagcggtggc
ctcatctcccaggagaagaccatcaaccttgtcaatgacatttttggagccggatttgat
acaattaccacagccatctcctggagccttttataccttgtgacatatcctgagatacag
aagaagatccagaaggagctggacacagtgattggccgggcgcggcggccccggctctcc
gacagaccccagctgccctatatggaggccttcatcctggagctcttccgacacacctcc
ttcgttcccttcaccatccctcacagcacaacaagggacacgacactgaatggcttctac
atccccaaggaacgccatgtcctcgtaaaccagtggcaggttaatcatgacccgaagctg
tggggggacccatccgagttccggccagagagattcctcactgccgatggcactgccatc
cacaagaccatgagtgagaaagttattctcttcggcatgggcaagcgccggtgcataggg
gaggtcctggccaagtgggaggtcttcctcttcctggccatcttgctgcagcagctagag
ttcagcgtgcctccaggcgtgaaagtggacctaacccccatctacgggctgaccatgaag
catgcccactgcaagcatttccaggcacatctgcgtttccccatcaaatga

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