KEGG   Sus scrofa (pig): 100511707
Entry
100511707         CDS       T01009                                 
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 precursor
  KO
K04521  beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100511707 (BACE1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ssc01002]
    100511707 (BACE1)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.46  memapsin 2
     100511707 (BACE1)
Peptidases and inhibitors [BR:ssc01002]
 Aspartic peptidases
  Family A1: pepsin family
   100511707 (BACE1)
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N PE-PGRS_C
Other DBs
NCBI-GeneID: 100511707
NCBI-ProteinID: NP_001276783
Ensembl: ENSSSCG00000015079
UniProt: A0A8D0JXI8
Position
9:complement(44640389..44665863)
AA seq 506 aa
MPGPTMAQALPWLLLWMGSGVLPAHSPQPGIRLPLRSGLGGAPLGLRLPRETDEEPEESS
RKGNFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQR
QLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSN
WEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSM
IIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNL
RLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGF
AVSACHVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCL
MVCQWRCLRCLRHQHDDFADDISLLK
NT seq 1521 nt   +upstreamnt  +downstreamnt
atgccagggcctaccatggcccaagcgctgccctggctcctgctatggatgggctccggg
gtgctgcctgcccacagcccccagcctggcatccggctacccctgcgaagcggccttggg
ggggcacccctggggctaaggctgccccgggagactgacgaggagcctgaggagtccagc
cggaagggcaactttgtggagatggtggacaacctgaggggcaagtccggtcagggctac
tacgtggagatgaccgtgggcagccccccacagacgctcaacatcctggtggacacaggc
agcagtaactttgctgtgggggctgccccccaccctttcctgcatcgctactaccagagg
cagctgtccagcacataccgggacctccggaagggtgtgtatgtgccctacacccagggc
aagtgggagggggagctgggcaccgacctggtgagcatcccccacggccccaacgtcact
gtgcgggccaacattgctgccatcactgagtcagacaagttcttcatcaatggctccaac
tgggagggcatcctggggctggcctacgcggagatcgccaggcccgacgactccttggag
ccgttctttgattccctggtaaagcagacccacgtgcccaacctcttctccctgcagctc
tgcggcgccggcttccccctcaaccagtcggaagtgctggcctcggttggtgggagcatg
atcatcgggggtatcgaccactcgctgtacacgggcagcctctggtacacacccatccgg
cgggagtggtattatgaggtgatcattgtgcgggtggagatcaatggacaggatctgaaa
atggactgcaaggagtacaactacgacaagagcattgtcgacagtggcaccaccaacctt
cgtttgcccaagaaagtgtttgaagctgccgtcaaatccatcaaggcagcctcctcgacg
gagaagttcccagatggtttctggttaggggaacagctggtgtgctggcaagcaggcacc
accccttggaacattttcccagtcatctcactctacctaatgggggaagtcaccaatcag
tccttccgcatcaccatccttccacagcaatatctgcggccagtagaagatgtggccacg
tcccaagacgactgctacaagttcgccatctcacagtcatccacaggcactgtcatggga
gctgttatcatggaaggcttctacgttgtctttgatcgggcccggaaacgaattggcttt
gcggtcagcgcctgccatgtgcacgatgagttcaggacagcagcagtggaaggccctttt
gtcaccccggacatggaagactgtggctacaacatcccacagacagatgaatcaaccctc
atgaccatagcctatgtcatggctgccatctgcgccctcttcatgctgccactctgcctc
atggtgtgccagtggcgctgcctccgctgcctgcgccatcagcacgatgactttgctgac
gacatctccctgctgaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (29)   

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