KEGG   Sus scrofa (pig): 397011
Entry
397011            CDS       T01009                                 
Symbol
OPTN
Name
(RefSeq) optineurin
  KO
K19946  optineurin
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04137  Mitophagy - animal
ssc04140  Autophagy - animal
ssc05014  Amyotrophic lateral sclerosis
ssc05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    397011 (OPTN)
   04137 Mitophagy - animal
    397011 (OPTN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    397011 (OPTN)
   05022 Pathways of neurodegeneration - multiple diseases
    397011 (OPTN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssc04131]
    397011 (OPTN)
Membrane trafficking [BR:ssc04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    397011 (OPTN)
 Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    397011 (OPTN)
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    397011 (OPTN)
  Xenophagy
   Cargo receptors
    397011 (OPTN)
SSDB
Motif
Pfam: CC2-LZ NEMO zf_C2H2_10 CMD Zn_ribbon_CLPX_N
Other DBs
NCBI-GeneID: 397011
NCBI-ProteinID: NP_999126
Ensembl: ENSSSCG00000023247
UniProt: Q7YS99
Position
10:complement(48532029..48582952)
AA seq 574 aa
MSHQPLSCLTEKGDSPTETTGNGPPTLAHPNLDTFTPHELLQQMRELLIENHQLKEAMKL
NNQAMKGRFEELSAWTEKQKEERLFFETQSKEAKERLTALSLENEKLKQELGKLKGKTER
SFEDLTGDPRVPKAEAEQEVEQLKTQVARLQAEKADLLGIVSELQLKLNSGGPSEDSFVE
IRMAEGEADAAMKEIKTSPGPIRTDSIDTSKSAEGTRNYLEFEELTVSQLLLCLREGNQK
VERLEIALKEAKERILDFEKKAKDRSETETQTEEHKEQEKEEEKSPETVGSEVEMLNLQV
TTLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELLYNNKKLELQVE
SMRSEIKMEQAKTEEEKSKLTTLQLTHNRLLQEYNNALKTIEELKRRESEKVDKVVLQEL
NGKLEMAEKALASKQLQMDEMKQTIAKQEKDLETMAVLRAQMEVYCSDFHAERAAREKIH
EEKEQLALQLAVLLKDDNAFEEGASRQSLMEMQSRHGARASDADQQAFLVQRGAEDRNWL
QQQQQNIPIHSCPKCGEVLPDIDTLLIHVTDCII
NT seq 1725 nt   +upstreamnt  +downstreamnt
atgtcccatcaacctctgagctgcctgactgagaagggggacagccccaccgaaaccaca
ggaaatggaccccccactctggctcacccaaaccttgacacgttcaccccacatgaactg
ctgcagcagatgagagagcttctaatcgagaaccatcagctgaaagaagccatgaagcta
aataatcaagctatgaaagggcgatttgaggagctttcagcctggacagagaagcagaag
gaagaacgccttttttttgagacccagagcaaagaagccaaagagcgcctaacggctctg
agtcttgaaaatgaaaaactgaagcaagaacttggaaaactaaaagggaaaactgaaagg
tcatttgaggacctcactggggaccccagggtccccaaggcggaagcagaacaggaagta
gaacagctgaagacccaggtggcacgccttcaagctgaaaaggcggatctgctgggcatc
gtgtctgaattgcagctcaagctgaactcaggtggcccctctgaagactcctttgttgaa
atcaggatggctgagggagaagcagatgcagcaatgaaggaaatcaagacaagtcctggg
cccataagaactgattccattgacacgagcaaatctgcagaaggtaccaggaattatttg
gaatttgaggaattaactgtgagccagctcctgctgtgtctaagggaaggaaaccagaag
gtggagagacttgaaatcgccctcaaggaagccaaagaaagaattttagattttgaaaag
aaagccaaggatcgttctgagactgagacccagacagaagagcacaaagaacaagagaaa
gaagaggagaaaagcccagaaactgttggaagtgaagtggaaatgttaaaccttcaggtg
acaaccctgtttaaggagcttcaggaggctcacacgaaactcagtgaagctgagctcatg
aagaagagacttcaagaaaaatgtcaggcacttgaaaggaaaaattctgcaaccccatca
gagctgaatgaaaagcaagagcttctttataataacaaaaagttggagctccaagtggaa
agcatgagatcagaaattaaaatggagcaagccaaaacagaagaggaaaagtccaaatta
actactctacagttgacccacaacaggcttcttcaagaatacaataatgcactgaaaaca
attgaggaactgaaaagaagagagtctgaaaaagtggataaggtggtgctgcaggaactg
aatggaaagctggaaatggcagagaaggccctggcttccaagcagctccaaatggatgag
atgaagcagaccattgccaagcaagagaaggacctggaaaccatggctgttctcagggct
cagatggaggtatactgttctgactttcatgctgaaagagcagcaagagagaagattcat
gaagaaaaggagcaactggcattgcagctggcagttttgctgaaagacgacaatgctttt
gaagagggagccagcaggcaatccttgatggaaatgcagagccgtcatggggcaagagca
agtgatgctgaccagcaggcttttcttgttcaaagaggagctgaggatagaaactggctg
caacagcaacaacagaatattccaattcattcttgccccaaatgtggagaagttctgcct
gacatagatacactactgattcacgttacggactgcatcatttaa

  All links  
Gene (14)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (23)   
   RefSeq(nuc) (5)   
   GenBank (9)   
   EMBL (9)   
Protein domain (5)   
   Pfam (5)   
All databases (49)   

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