KEGG   Sus scrofa (pig): 397048
Entry
397048            CDS       T01009                                 

Gene name
SRD5A2
Definition
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00140  Steroid hormone biosynthesis
ssc05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    397048 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    397048 (SRD5A2)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     397048 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 PEMT
Other DBs
NCBI-GeneID: 397048
NCBI-ProteinID: NP_999153
Ensembl: ENSSSCG00000008521
UniProt: O18765
Position
3
AA seq 254 aa
MPVRCQQSPVLAGSATLAALGALALYFAEPSGYGKYTESLTPAAIRLPARAAWFLQELPS
FVVPAGILAGQPRSLFGPPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEVIYKI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYVKMFE
DYPKSRKALIPFIF
NT seq 765 nt   +upstreamnt  +downstreamnt
atgcctgttcgctgccagcagagcccggtgctggcgggcagcgccactttggctgccctg
ggggcactggccctgtacttcgcggagccctctggctacgggaagtacacggagagcctg
acgcccgcggctatccgcctgccagcccgtgccgcctggttcctgcaggagctgccctcc
ttcgtggtgcccgcggggatcctcgccgggcagccccgttctctcttcggcccgcctgcg
actgtgcttctgggcctcttctgcgcacattacttccacaggacatttgtttactcactg
ctcactagagggaggccttttccagttgtattccttttcagaggctttgtcttctgcatg
ggaaatggactccttcaaggctactatctggtttactgtgccgaataccctgctgagtgg
tacacagacatacggtttagcctaggtgtgttcttatttattttgggcatgggaatcaac
attcacagcgactatatattgcgccagctcaggaagcctggagaagtcatctataagatt
ccacaaggtggcttgttcacgtacgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccttggccacttggtcccttccagcacttgcatttgcatttttctcg
ctttgtttccttgggctgcgagcttttcaccatcataggttctacgtcaagatgtttgag
gactaccccaagtctcgaaaagcccttattccatttatcttttaa

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