KEGG T03912: SULC

Saccharolobus solfataricus SARC-C: SULC_0192

Entry

SULC_0192         CDS       T03912

Symbol

thiD

Name

(GenBank) bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase

K21219

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

ssof Saccharolobus solfataricus SARC-C

Pathway

ssof00730

Thiamine metabolism

ssof01100

Metabolic pathways

ssof01240

Biosynthesis of cofactors

Module

ssof_M00896

Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP

Brite

KEGG Orthology (KO) [BR:ssof00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    SULC_0192 (thiD)
Enzymes [BR:ssof01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     SULC_0192 (thiD)
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     SULC_0192 (thiD)
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     SULC_0192 (thiD)

SSDB

Motif

Pfam:

Phos_pyr_kin ThiP_synth PfkB DUF3074

Other DBs

NCBI-ProteinID:

AKA75334

UniProt:

Q9P9G9

Position

complement(172735..174069)

AA seq 444 aa
MIKPVGMSIAGLDTGNGAGGETDLRVFEVLGIHGVFAITAITAQSTKGIKDITVVNPEFL
KKQIETLLEDFKVEAVKIGMIYTKEQFQVVNELLNDYFLVADPVLYAKDGTPLIRDIEEY
KKIILPKVKVITPNIIEASAISGVKIEKESDVVIVCKKLRDSYNIPYVIIKGGHSKGDYS
FDYMCNDEGLYKIGYKRLQAKDTHGTGSVFATALTAEYIKIRDLKLAFRKARDFVQTSIE
YGLNIGKGIGPVNVSVEIMKKSMKYEAVEEMRRFADFAENNDRFWILIPEVQSNLAHSIK
PEYVRDLNDIATFRGRIIRRWDKKVIVGHPVVFGNPTHTARMLLSLILKGKDSTCLMNIR
YDDKIVESFKRIGYETIEINRELEPAHGEGKTMQWIIEYVSSEYGGIPNVIYDKGTKGKE
AMIRFWTKNMEEMIEALDNLLKML

NT seq 1335 nt +upstreamnt +downstreamnt
atgattaaacctgttggtatgagcatagctggattggatactggaaatggggctggtgga
gagactgacttaagagtttttgaagtattaggaatccacggagtttttgctatcactgcg
ataacagctcaaagtacaaaaggcataaaagatatcactgttgttaatcctgagtttctt
aaaaagcagatagaaactttactcgaggatttcaaagtggaagctgtaaagataggaatg
atatatactaaagaacagtttcaggttgtaaatgaattattaaatgattactttttagta
gcagatccggtactttatgcgaaagatggaactccgctgattagagacattgaagaatat
aagaagataattttgccaaaagttaaagtaataacgccaaatataatagaagcatctgca
attagcggtgtcaaaatagaaaaggagagcgatgtagtaattgtatgtaagaaattaagg
gatagttataatattccctacgtgataatcaagggaggccatagtaaaggagattatagt
ttcgattatatgtgtaatgatgaaggactatacaagataggatataaaaggttgcaggca
aaggatacgcatggtactggaagcgtatttgcaactgcacttactgcagaatacataaag
ataagggatttaaaattggcctttaggaaggctagagatttcgttcaaacctcaatagaa
tatggacttaacataggaaaaggtataggaccagttaacgtaagtgttgaaattatgaag
aagtctatgaaatatgaagcagttgaggaaatgaggagatttgcggattttgccgaaaat
aacgatagattctggattttaatccctgaagtacaatcaaatctagcacatagtataaaa
ccagaatacgttagggatctaaatgatattgctacatttaggggtagaataataaggaga
tgggataaaaaggtaattgttggacatccagtggtgtttggaaaccctacccatacagct
cgaatgctgttgtcgctcattctcaagggaaaggatagtacttgcttaatgaatattaga
tatgacgataagatagttgagagttttaagagaattgggtatgaaacaattgagattaat
agggaactagaacctgcccatggagaaggaaagacaatgcaatggattattgagtatgta
agtagcgaatatggtggcataccgaatgtaatttatgataagggaactaagggaaaggag
gcaatgattaggttttggacaaaaaacatggaagagatgatagaagctttagataattta
ttaaaaatgctgtaa

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