KEGG   Spirochaeta thermophila DSM 6192: STHERM_c20780
Entry
STHERM_c20780     CDS       T01315                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sta  Spirochaeta thermophila DSM 6192
Pathway
sta00290  Valine, leucine and isoleucine biosynthesis
sta00620  Pyruvate metabolism
sta01100  Metabolic pathways
sta01110  Biosynthesis of secondary metabolites
sta01210  2-Oxocarboxylic acid metabolism
sta01230  Biosynthesis of amino acids
Module
sta_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sta00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    STHERM_c20780
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    STHERM_c20780
Enzymes [BR:sta01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     STHERM_c20780
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ADN03009
UniProt: E0RQV3
Position
2297240..2298901
AA seq 553 aa
MKNAHKYRPFPFRVSLPDRTWPDKHITAPPAWCSVDLRDGNQALPVPMNVDQKLEFFKLL
CDTGFKEIEVGFPSASQIEYDFTRQLIEEHLIPDDVYIQVLTQARPHLIDRTVEAVQGAK
KVILHMYVATSVMHRTIVFKRSKEEVKKIAVDGTLYMKSLLPRLAGSEVVYEFSPEAFNM
TEPEFALEVCEAVVEAWNPKETGGKVILNLPATVEGSTPNVYADQIEWFCRNFSRRDEVI
ISVHTHNDRGTGVAATELALLAGAERVEGTLFGNGERTGNLDIVAVALNMYAEGVDPGLD
LSDLPRIRSVYERCTGMTIHPRHPYAGDLVFTAFSGSHQDAIKKAMDLLKTEKKDYWEVP
YLPIDPMDIGRSYKAIIRINSQSGKGGVSYVLQEEFGLEIPKGMHPEVGKKVNEVSDALV
RELSPQEVYEVFEKHFLNLSDPYDLVSYRIETEGKTVQITARVKERGEEKVLTGTGNGPI
DAFVHAMKGQGWNDFEITDYHEQALGKGSDTEAVAYIRITRDGRDYWGAGRHTDTIAASI
HALLSAYNRVYTK
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgaagaacgcacacaagtaccggcccttccccttccgggtctctctccccgacaggacg
tggcccgacaagcacatcaccgctccacctgcatggtgcagcgtcgacctgcgtgacggc
aaccaagccctccctgtccccatgaacgtggaccagaagctcgagttcttcaagctcctc
tgtgacacggggttcaaggagatcgaagtcggcttcccctccgcctcccagatagagtac
gacttcacccgccaactcatagaggaacacctcatccccgacgatgtgtacatccaggtc
cttacccaggcacgcccccacctcatcgatcgtaccgtggaggccgtgcagggggcgaag
aaggtcattctccacatgtacgtagcgacctcggtgatgcacaggaccatcgtcttcaaa
cgttctaaagaagaggtgaagaagattgcagtggacggcaccctctacatgaagtccctc
ctcccccgcctcgccggtagtgaggtggtctacgagttctctccagaagccttcaacatg
accgaacccgagttcgccctggaggtatgcgaggccgtggtggaggcatggaatccaaag
gagacgggcggcaaggtgatcctcaacctccccgccacggtggagggctccacgcccaat
gtctacgccgaccagatcgagtggttctgccggaacttctcgaggcgggacgaggtgatc
atcagcgtacacacccacaacgaccgtggcaccggtgtcgcggccaccgaactcgccctc
ctggccggtgccgaacgggtggaaggcaccctcttcggtaacggcgagcgaaccgggaac
ctcgacatcgtggcggtcgccctcaacatgtacgcggagggagtggatccgggcctcgac
ctctcggacctgcctcggatccggagtgtgtacgagcgctgtaccggcatgaccatccac
ccgaggcacccctatgcaggggatctcgtcttcaccgccttctccggttcgcaccaggac
gccatcaagaaggccatggacctcctcaagaccgagaagaaggactactgggaggtcccc
taccttcccatcgatcctatggacataggccggagctacaaggccatcatccgcatcaac
agccagagcgggaagggcggggtctcctacgtgctccaggaggagttcggcctcgagatc
cccaaaggcatgcaccccgaggtggggaaaaaggtgaacgaggtctccgacgccctcgta
cgggagctctcccctcaggaggtctacgaggtcttcgaaaagcacttcctcaatctctcc
gatccatacgacctggtatcctacaggatcgagaccgaggggaagaccgtccagatcacc
gcccgggtgaaggaacgaggcgaggagaaggtcctcaccgggaccgggaacggccccatc
gacgcctttgtccacgcgatgaagggccaggggtggaacgatttcgagatcaccgactac
cacgaacaggcactgggcaaaggttcggacaccgaggcggtggcctatatccggatcacg
agggatggacgggactactggggcgcaggtcgtcacaccgacaccatcgccgcgagcatc
cacgccctcctgagcgcctacaacagagtctacacgaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (46)   

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