KEGG   Streptococcus sp. NPS 308: SNAG_0891
Entry
SNAG_0891         CDS       T05541                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
strn  Streptococcus sp. NPS 308
Pathway
strn00290  Valine, leucine and isoleucine biosynthesis
strn00620  Pyruvate metabolism
strn01100  Metabolic pathways
strn01110  Biosynthesis of secondary metabolites
strn01210  2-Oxocarboxylic acid metabolism
strn01230  Biosynthesis of amino acids
Module
strn_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:strn00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SNAG_0891 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SNAG_0891 (leuA)
Enzymes [BR:strn01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SNAG_0891 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer IF-2
Other DBs
NCBI-ProteinID: BAV79767
UniProt: A0A1E1GAG3
Position
859769..861331
AA seq 520 aa
MRRVEFLDTSLRDGEQTPGVNFSIKEKVAIARQLEKWGISAIEAGFPAASPDSFTAVQEI
AKVLKKTSVTGLARSVKSDIDACYEALKDAKYPQVHVFIATSPIHRKYKLNKSKEEILEA
ISEHVSYARSKFEIVEFSPEDATRTELDFLLQVVQTAVDAGATYINIPDTVGFTTPEEYG
AIFKYLIENVKTDRQIIYSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIGERAGNAAL
EEIAVALNIRQDYYQAETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNAFSHESGIHQ
DGVLKNPLTYEIITPELVGVKSNSLPLGKLSGRHAFVEKLRDLALDFTEEDIKPLFAKFK
ALADKKQEITDADIRALVAGIMVENPEGFHFDDLQLQTHADKDIEAIVSLANMDGEKVEF
NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDAQARVLVTVENRDTETIFNAAG
LDFDVLKASAIAYINANTFVQKENAGEMGHSVSYRDMPSV
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgcgtagagttgagtttttagataccagtctccgtgatggtgagcagacaccaggcgtt
aacttttcaatcaaggaaaaggtcgccattgcaagacagctggagaaatgggggatttcg
gctatcgaagctggttttccagcggcgagtccagattcatttacagcagttcaggagatt
gccaaggtcttgaagaaaacatcggtgacaggtttggcccgttcggtcaagtctgatata
gatgcttgttatgaggcgctaaaggatgccaagtatcctcaggttcacgtctttatcgcg
accagtccgattcaccgtaagtataagctcaataagagcaaggaagagattttggaagca
atcagtgaacatgtttcttatgctcgttctaagtttgaaattgtcgaattttctccagag
gatgcgaccagaacagaattggatttcctcttgcaagttgttcagacagctgtggatgca
ggtgcgacctacatcaatatccctgacacggttggatttacgacgccagaggaatatggt
gccatcttcaaatacttaattgagaatgtcaagaccgatcgtcagattatctattctcct
cactgtcatgatgatctcggaatggcagtagctaatagtcttgctgctgttaagaatgga
gcaggacgagtcgaaggaaccatcaatggtatcggggagcgagctggcaatgctgctttg
gaagaaattgcagtggcgcttaatattcgccaagattactaccaagcagaaaccagtatt
gtcctaaacgaaaccatcaatacgtcagaaatggtttctcgcttctcaggtattccagtt
cctaaaaacaaggcggttgttggaggaaatgccttctctcatgaatcgggtattcaccaa
gatggagtccttaaaaatcctcttacctatgaaattattacacctgaattggttggtgtc
aagagtaacagtcttccgcttggaaaattgtccggtcgccacgcttttgtagaaaaacta
agagatttggctctagactttactgaagaagatatcaaaccactctttgctaagttcaag
gcactagcggacaaaaagcaagaaatcacagatgcagatattcgtgctctggtagctgga
atcatggttgaaaacccagaaggctttcactttgatgatttacaacttcaaacccatgcg
gataaagacattgaagcaattgtcagccttgctaatatggatggtgagaaggttgagttt
aatgcgaccggacaaggttctgtagaggcaatcttcaacgctatcgataagttcttcaat
caatccgttcgcttggtgtcttacacaattgatgcggtgacagatgggatcgatgcccag
gctcgtgtcttggtcactgttgaaaacagagatacagaaaccatctttaacgcggcaggt
cttgacttcgatgtattgaaggcttcggcgattgcttatatcaatgccaatacctttgtt
caaaaggagaatgctggtgagatggggcacagcgtttcctaccgagacatgcctagtgtg
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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